The Sentinel

Human Rights Action :: Humanitarian Response :: Health :: Education :: Heritage Stewardship ::
Sustainable Development
__________________________________________________
Week ending 30 July 2016

This weekly digest is intended to aggregate and distill key content from a broad spectrum of practice domains and organization types including key agencies/IGOs, NGOs, governments, academic and research institutions, consortia and collaborations, foundations, and commercial organizations. We also monitor a spectrum of peer-reviewed journals and general media channels. The Sentinel’s geographic scope is global/regional but selected country-level content is included. We recognize that this spectrum/scope yields an indicative and not an exhaustive product. Comments and suggestions should be directed to:

David R. Curry
Editor &
Founding Managing Director
GE2P2 Global Foundation – Center for Governance, Evidence, Ethics, Policy, Practice
david.r.curry@ge2p2center.net

pdf version: The Sentinel_ week ending 30 July 2016

 

The Sentinel will resume publication on 20 August 2016 following annual leave for the Editor.

The Sentinel

Human Rights Action :: Humanitarian Response :: Health :: Education :: Heritage Stewardship ::
Sustainable Development
__________________________________________________
Week ending 23 July 2016

This weekly digest is intended to aggregate and distill key content from a broad spectrum of practice domains and organization types including key agencies/IGOs, NGOs, governments, academic and research institutions, consortia and collaborations, foundations, and commercial organizations. We also monitor a spectrum of peer-reviewed journals and general media channels. The Sentinel’s geographic scope is global/regional but selected country-level content is included. We recognize that this spectrum/scope yields an indicative and not an exhaustive product. Comments and suggestions should be directed to:

David R. Curry
Editor &
Founding Managing Director
GE2P2 Global Foundation – Center for Governance, Evidence, Ethics, Policy, Practice
david.r.curry@ge2p2center.net

pdf version: The Sentinel_ week ending 23 July 2016

Contents
:: Week in Review
:: Key Agency/IGO/Governments Watch – Selected Updates from 30+ entities
:: INGO/Consortia/Joint Initiatives Watch – Media Releases, Major Initiatives, Research
:: Foundation/Major Donor Watch -Selected Updates
:: Journal Watch – Key articles and abstracts from 100+ peer-reviewed journals

:: Journal Watch

:: Journal Watch

The Sentinel will track key peer-reviewed journals which address a broad range of interests in human rights, humanitarian response, health and development. It is not intended to be exhaustive. We will add to those monitored below as we encounter relevant content and upon recommendation from readers. We selectively provide full text of abstracts and other content but note that successful access to some of the articles and other content may require subscription or other access arrangement unique to the publisher. Please suggest additional journals you feel warrant coverage.

BMC Health Services Research (Accessed 23 July 2016)

BMC Health Services Research
http://www.biomedcentral.com/bmchealthservres/content
(Accessed 23 July 2016)

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Research article
Human trafficking and severe mental illness: an economic analysis of survivors’ use of psychiatric services
Previous studies have found a high prevalence of depression and post-traumatic stress disorder (PTSD) among survivors of human trafficking. European countries are required to assist trafficked people in their …
Maria Cary, Siân Oram, Louise M. Howard, Kylee Trevillion and Sarah Byford
BMC Health Services Research 2016 16:284
Published on: 19 July 2016

BMC Infectious Diseases (Accessed 23 July 2016)

BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 23 July 2016)

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Research article
Predicting the international spread of Middle East respiratory syndrome (MERS)
The Middle East respiratory syndrome (MERS) associated coronavirus has been imported via travelers into multiple countries around the world. In order to support risk assessment practice, the present study aime...
Kyeongah Nah, Shiori Otsuki, Gerardo Chowell and Hiroshi Nishiura
BMC Infectious Diseases 2016 16:356
Published on: 22 July 2016

The potential to expand antiretroviral therapy by improving health facility efficiency: evidence from Kenya, Uganda, and Zambia

BMC Medicine
http://www.biomedcentral.com/bmcmed/content
(Accessed 23 July 2016)

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Research article
The potential to expand antiretroviral therapy by improving health facility efficiency: evidence from Kenya, Uganda, and Zambia
Since 2000, international funding for HIV has supported scaling up antiretroviral therapy (ART) in sub-Saharan Africa. However, such funding has stagnated for years, threatening the sustainability and reach of…
Laura Di Giorgio, Mark W. Moses, Nancy Fullman, Alexandra Wollum, Ruben O. Conner, Jane Achan, Tom Achoki, Kelsey A. Bannon, Roy Burstein, Emily Dansereau, Brendan DeCenso, Kristen Delwiche, Herbert C. Duber, Emmanuela Gakidou, Anne Gasasira, Annie Haakenstad…
BMC Medicine 2016 14:108
Published on: 20 July 2016

Does mobile phone ownership predict better utilization of maternal and newborn health services? a cross-sectional study in Timor-Leste

BMC Pregnancy and Childbirth
http://www.biomedcentral.com/bmcpregnancychildbirth/content
(Accessed 23 July 2016)

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Research article
Does mobile phone ownership predict better utilization of maternal and newborn health services? a cross-sectional study in Timor-Leste
Increasingly popular mobile health (mHealth) programs have been proposed to promote better utilization of maternal, newborn and child health services. However, women who lack access to a mobile phone are often...
Juan Nie, Jennifer Anna Unger, Susan Thompson, Marisa Hofstee, Jing Gu and Mary Anne Mercer
BMC Pregnancy and Childbirth 2016 16:183
Published on: 23 July 2016

BMC Public Health (Accessed 23 July 2016)

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 23 July 2016)

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Research article
An analysis of three levels of scaled-up coverage for 28 interventions to avert stillbirths and maternal, newborn and child mortality in 27 countries in Latin America and the Caribbean with the Lives Saved Tool (LiST)
Action to avert maternal and child mortality was propelled by the Millennium Development Goals (MDGs) in 2000. The Latin American and Caribbean (LAC) region has shown promise in achieving the MDGs in many coun…
Lauren Arnesen, Thomas O’Connell, Luisa Brumana and Pablo Durán
BMC Public Health 2016 16:613
Published on: 22 July 2016

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Research article
Social capital and healthy ageing in Indonesia
A large international literature has found a positive association between social capital and measures of physical and mental health. However, there is a paucity of research on the links between social capital …
Junran Cao and Anu Rammohan
BMC Public Health 2016 16:631
Published on: 22 July 2016

Excess mortality in refugees, internally displaced persons and resident populations in complex humanitarian emergencies (1998–2012) – insights from operational data

Conflict and Health
http://www.conflictandhealth.com/
[Accessed 23 July 2016]

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Research
Excess mortality in refugees, internally displaced persons and resident populations in complex humanitarian emergencies (1998–2012) – insights from operational data
Peter Heudtlass, Niko Speybroeck and Debarati Guha-Sapir
Conflict and Health 2016 10:15
Published on: 20 July 2016
Abstract
Background
Complex humanitarian emergencies are characterised by a break-down of health systems. All-cause mortality increases and non-violent excess deaths (predominantly due to infectious diseases) have been shown to outnumber violent deaths even in exceptionally brutal conflicts. However, affected populations are very heterogeneous and refugees, internally displaced persons (IDPs) and resident (non-displaced) populations differ substantially in their access to health services. We aim to show how this translates into health outcomes by quantifying excess all-cause mortality in emergencies by displacement status.
Methods
As standard data sources on mortality only poorly represent these populations, we use data from CEDAT, a database established by aid agencies to share operational health data collected for planning, monitoring and evaluation of humanitarian aid. We obtained 1759 Crude Death Rate (CDR) estimates from emergency assessments conducted between 1998 and 2012. We define excess mortality as the ratio of CDR in emergency assessments over ‘baseline CDR’ (as reported in the World Development Indicators). These death rate ratios (DRR) are calculated separately for all emergency assessments and their distribution is analysed by displacement status using non-parametric statistics.
Results
We found significant excess mortality in IDPs (median DRR: 2.5; 95 % CI: [2.2, 2.93]) and residents (median DDR: 1.51; 95 % CI: [1.47, 1.58]). Mortality in refugees however is not significantly different from baseline mortality in the host countries (median DRR: 0.94, 95 % CI: [0.73, 1.1]).
Conclusions
Aid agencies report the highest excess mortality rates among IDPs, followed by resident populations. In absolute terms however, due to their high share in the total number of people at risk, residents are likely to account for most of the excess deaths in today’s emergencies. Further research is needed to clarify whether the low estimates of excess mortality in refugees are the result of successful humanitarian interventions or due to limitations of our methods and data.

A scoping review of video gaming in rehabilitation

Disability and Rehabilitation: Assistive Technology
Volume 11, Issue 6, 2016
http://informahealthcare.com/toc/idt/current

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Review Article
A scoping review of video gaming in rehabilitation
pages 445-453
DOI:10.3109/17483107.2015.1029538
Kelly E. Ravenek, Dalton L. Wolfe & Sander L. Hitzig
Abstract
Purpose: To examine the scope of the peer-reviewed literature on the use of commercially available video gaming in rehabilitation. Methods: Five databases (SCOPUS, Cochrane, PsycINFO, PubMed and CINAHL) were searched for articles published between January 1990 and January 2014. The reference lists of selected articles were also reviewed to identify other relevant studies. Results: Thirty articles met the inclusion criteria. Commercially available video gaming in rehabilitation was most commonly recommended by physiotherapists (50% or 15/30 studies) for populations at risk for falls or with decreased balance (67% or 19/30 studies). The most commonly used target outcomes were those assessing balance and/or fall prevention, with the Berg Balance Scale being the most frequently used (53% or 16/30 studies) outcome measure. The Nintendo Wii was the most prevalent gaming system (90% or 27/30 studies) used in the identified studies. Conclusion: Video gaming in rehabilitation is widely used by clinicians. Preliminary findings show that video gaming technology can be applied across a wide variety of rehabilitation populations, with some evidence showing clinical gains in physical functioning (e.g. gait and balance). There is a need for more robust clinical trials evaluating the efficacy of using video game systems as an adjunct to conventional rehabilitation.

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Implications for Rehabilitation
:: Video gaming is a readily available technology that has been suggested as an enjoyable and motivating activity that engages patients in rehabilitation programming.
:: Video gaming is becoming an increasingly popular adjunct to traditional therapy.
:: Video gaming is most commonly used by physical therapists in a hospital setting for those with balance impairments.
:: Video gaming has been shown to improve functional outcomes.

Health Policy and Planning – Volume 31 Issue 6 July 2016

Health Policy and Planning
Volume 31 Issue 6 July 2016
http://heapol.oxfordjournals.org/content/current

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Original Articles
The emergence of the vertical birth in Ecuador: an analysis of agenda setting and policy windows for intercultural health
Ana Llamas and Susannah Mayhew
Health Policy Plan. (2016) 31 (6): 683-690 doi:10.1093/heapol/czv118
Abstract
Maternal mortality continues to claim the lives of thousands of women in Latin America despite the availability of effective treatments to avert maternal death. In the past, efforts to acknowledge cultural diversity in birth practices had not been clearly integrated into policy. However, in Otavalo (Ecuador) a local hospital pioneered the implementation of the ‘Vertical Birth’—a practical manifestation of an intercultural health policy aimed at increasing indigenous women’s access to maternity care. Drawing on agenda-setting theory, this qualitative research explores how the vertical birth practice made it onto the local policy agenda and the processes that allowed actors to seize a window of opportunity allowing the vertical birth practice to emerge. Our results show that the processes that brought about the vertical birth practice took place over a prolonged period of time and resulted from the interplay between various factors. Firstly, a maternal health policy community involving indigenous actors played a key role in identifying maternal mortality as a policy problem, defining its causes and framing it as an indigenous rights issue. Secondly, previous initiatives to address maternal mortality provided a wealth of experience that gave these actors the knowledge and experience to formulate a feasible policy solution and consolidate support from powerful actors. Thirdly, the election of a new government that had incorporated the demands of the indigenous movement opened up a window of opportunity to push intercultural health policies such as the vertical birth. We conclude that the socioeconomic and political changes at both national and local level allowed the meaningful participation of indigenous actors that made a critical contribution to the emergence of the vertical birth practice. These findings can help us advance our knowledge of strategies to set the agenda for intercultural maternal health policy and inform future policy in similar settings. Our results also show that Kingdon’s model was useful in explaining how the VB practice emerged but also that it needs modifications when applied to low and middle income countries.

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Original Articles
Feasibility and acceptability of delivering adolescent health interventions alongside HPV vaccination in Tanzania
Deborah Watson-Jones, Shelley Lees, Joseph Mwanga, Nyasule Neke, John Changalucha, Nathalie Broutet, Ibrahim Maduhu, Saidi Kapiga, Venkatraman Chandra-Mouli, Paul Bloem,
and David A Ross
Health Policy Plan. (2016) 31 (6): 691-699 doi:10.1093/heapol/czv119
Abstract
Background: Human papillomavirus (HPV) vaccination offers an opportunity to strengthen provision of adolescent health interventions (AHI). We explored the feasibility of integrating other AHI with HPV vaccination in Tanzania.
Methods: A desk review of 39 policy documents was preceded by a stakeholder meeting with 38 policy makers and partners. Eighteen key informant interviews (KIIs) with health and education policy makers and district officials were conducted to further explore perceptions of current programs, priorities and AHI that might be suitable for integration with HPV vaccination.
Results: Fourteen school health interventions (SHI) or AHI are currently being implemented by the Government of Tanzania. Most are delivered as vertical programmes. Coverage of current programs is not universal, and is limited by financial, human resource and logistic constraints. Limited community engagement, rumours, and lack of strategic advocacy has affected uptake of some interventions, e.g. tetanus toxoid (TT) immunization. Stakeholder and KI perceptions and opinions were limited by a lack of experience with integrated delivery and AHI that were outside an individual’s area of expertise and experience. Deworming and educational sessions including reproductive health education were the most frequently mentioned interventions that respondents considered suitable for integrated delivery with HPV vaccine.
Conclusions: Given programme constraints, limited experience with integrated delivery and concern about real or perceived side-effects being attributed to the vaccine, it will be very important to pilot-test integration of AHI/SHI with HPV vaccination. Selected interventions will need to be simple and quick to deliver since health workers are likely to face significant logistic and time constraints during vaccination visits.

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Editor’s Choice:
BRICS countries and the global movement for universal health coverage
Fabrizio Tediosi, Aureliano Finch, Christina Procacci, Robert Marten, and Eduardo Missoni
Health Policy Plan. (2016) 31 (6): 717-728 doi:10.1093/heapol/czv122
Abstract
This article explores BRICS’ engagement in the global movement for Universal Health Coverage (UHC) and the implications for global health governance. It is based on primary data collected from 43 key informant interviews, complemented by a review of BRICS’ global commitments supporting UHC. Interviews were conducted using a semi-structured questionnaire that included both closed- and open-ended questions. Question development was informed by insights from the literature on UHC, Cox’s framework for action, and Kingdon’s multiple-stream theory of policy formation. The closed questions were analysed with simple descriptive statistics and the open-ended questions using grounded theory approach. The analysis demonstrates that most BRICS countries implicitly supported the global movement for UHC, and that they share an active engagement in promoting UHC. However, only Brazil, China and to some extent South Africa, were recognized as proactively pushing UHC in the global agenda. In addition, despite some concerted actions, BRICS countries seem to act more as individual countries rather that as an allied group. These findings suggest that BRICS are unlikely to be a unified political block that will transform global health governance. Yet the documented involvement of BRICS in the global movement supporting UHC, and their focus on domestic challenges, shows that BRICS individually are increasingly influential players in global health. So if BRICS countries should probably not be portrayed as the centre of future political community that will transform global health governance, their individual involvement in global health, and their documented concerted actions, may give greater voice to low- and middle-income countries supporting the emergence of multiple centres of powers in global health.

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Review
Framing and the health policy process: a scoping review
Adam D Koon, Benjamin Hawkins, and Susannah H Mayhew
Health Policy Plan. (2016) 31 (6): 801-816 doi:10.1093/heapol/czv128
Abstract
Framing research seeks to understand the forces that shape human behaviour in the policy process. It assumes that policy is a social construct and can be cast in a variety of ways to imply multiple legitimate value considerations. Frames provide the cognitive means of making sense of the social world, but discordance among them forms the basis of policy contestation. Framing, as both theory and method, has proven to generate considerable insight into the nature of policy debates in a variety of disciplines. Despite its salience for understanding health policy debates; however, little is known about the ways frames influence the health policy process. A scoping review using the Arksey and O’Malley framework was conducted. The literature on framing in the health sector was reviewed using nine health and social science databases. Articles were included that explicitly reported theory and methods used, data source(s), at least one frame, frame sponsor and evidence of a given frame’s effect on the health policy process. A total of 52 articles, from 1996 to 2014, and representing 12 countries, were identified. Much of the research came from the policy studies/political science literature (n = 17) and used a constructivist epistemology. The term ‘frame’ was used as a label to describe a variety of ideas, packaged as values, social problems, metaphors or arguments. Frames were characterized at various levels of abstraction ranging from general ideological orientations to specific policy positions. Most articles presented multiple frames and showed how actors advocated for them in a highly contested political process. Framing is increasingly an important, yet overlooked aspect of the policy process. Further analysis on frames, framing processes and frame conflict can help researchers and policymakers to understand opaque and highly charged policy issues, which may facilitate the resolution of protracted policy controversies.

Health Research Policy and Systems [Accessed 23 July 2016]

Health Research Policy and Systems
http://www.health-policy-systems.com/content
[Accessed 23 July 2016]

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Research
Embedding research in health systems: lessons from complexity theory
Internationally, there has been increasing focus on creating health research systems. This article aims to investigate the challenges of implementing apparently simple strategies to support the development of …
Louise Caffrey, Charles Wolfe and Christopher McKevitt
Health Research Policy and Systems 2016 14:54
Published on: 22 July 2016

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Research
Developing the African national health research systems barometer
A functional national health research system (NHRS) is crucial in strengthening a country’s health system to promote, restore and maintain the health status of its population. Progress towards the goal of univ...
Joses Muthuri Kirigia, Martin Okechukwu Ota, Flavia Senkubuge, Charles Shey Wiysonge and Bongani M. Mayosi
Health Research Policy and Systems 2016 14:53
Published on: 22 July 2016

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Commentary
A global call for action to include gender in research impact assessment
Global investment in biomedical research has grown significantly over the last decades, reaching approximately a quarter of a trillion US dollars in 2010. However, not all of this investment is distributed eve…
Pavel V. Ovseiko, Trisha Greenhalgh, Paula Adam, Jonathan Grant, Saba Hinrichs-Krapels, Kathryn E. Graham, Pamela A. Valentine, Omar Sued, Omar F. Boukhris, Nada M. Al Olaqi, Idrees S. Al Rahbi, Anne-Maree Dowd, Sara Bice, Tamika L. Heiden, Michael D. Fischer, Sue Dopson…
Health Research Policy and Systems 2016 14:50
Published on: 19 July 2016

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Research
Health systems research in fragile and conflict-affected states: a research agenda-setting exercise
There is increasing interest amongst donors in investing in the health sectors of fragile and conflict-affected states, although there is limited research evidence and research funding to support this. Agreein…
Aniek Woodward, Egbert Sondorp, Sophie Witter and Tim Martineau
Health Research Policy and Systems 2016 14:51
Published on: 21 July 2016

The Lancet – Jul 23, 2016

The Lancet
Jul 23, 2016 Volume 388 Number 10042 p307-436
http://www.thelancet.com/journals/lancet/issue/current

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Articles
The burden of mental, neurological, and substance use disorders in China and India: a systematic analysis of community representative epidemiological studies
Fiona J Charlson, Amanda J Baxter, Hui G Cheng, Rahul Shidhaye, Harvey A Whiteford
Summary
Background
China and India jointly account for 38% of the world population, so understanding the burden attributed to mental, neurological, and substance use disorders within these two countries is essential. As part of the Lancet/Lancet Psychiatry China–India Mental Health Alliance Series, we aim to provide estimates of the burden of mental, neurological, and substance use disorders for China and India from the Global Burden of Disease Study 2013 (GBD 2013).
Methods
In this systematic analysis for community representative epidemiological studies, we conducted systematic reviews in line with PRISMA guidelines for community representative epidemiological studies. We extracted estimates of prevalence, incidence, remission and duration, and mortality along with associated uncertainty intervals from GBD 2013. Using these data as primary inputs, DisMod-MR 2.0, a Bayesian meta-regression instrument, used a log rate and incidence-prevalence-mortality mathematical model to develop internally consistent epidemiological models. Disability-adjusted life-year (DALY) changes between 1990 and 2013 were decomposed to quantify change attributable to population growth and ageing. We projected DALYs from 2013 to 2025 for mental, neurological, and substance use disorders using United Nations population data.
Findings
Around a third of global DALYs attributable to mental, neurological, and substance use disorders were found in China and India (66 million DALYs), a number greater than all developed countries combined (50 million DALYs). Disease burden profiles differed; India showed similarities with other developing countries (around 50% of DALYs attributable to non-communicable disease), whereas China more closely resembled developed countries (around 80% of DALYs attributable to non-communicable disease). The overall population growth in India explains a greater proportion of the increase in mental, neurological, and substance use disorder burden from 1990 to 2013 (44%) than in China (20%). The burden of mental, neurological, and substance use disorders is estimated to increase by 10% in China and 23% in India between 2013 and 2025.
Interpretation
The current and projected burden of mental, neurological, and substance use disorders in China and India warrants the urgent prioritisation of programmes focused on targeted prevention, early identification, and effective treatment.
Funding
China Medical Board, Bill & Melinda Gates Foundation.
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Series
Transgender health
Transgender people: health at the margins of society
Sam Winter, Milton Diamond, Jamison Green, Dan Karasic, Terry Reed, Stephen Whittle, Kevan Wylie

Transgender health
Serving transgender people: clinical care considerations and service delivery models in transgender health
Kevan Wylie, Gail Knudson, Sharful Islam Khan, Mireille Bonierbale, Suporn Watanyusakul, Stefan Baral

Transgender health
Global health burden and needs of transgender populations: a review
Sari L Reisner, Tonia Poteat, JoAnne Keatley, Mauro Cabral, Tampose Mothopeng, Emilia Dunham, Claire E Holland, Ryan Max, Stefan D Baral

Beyond the Ebola Battle — Winning the War against Future Epidemics

New England Journal of Medicine
July 21, 2016 Vol. 375 No. 3
http://www.nejm.org/toc/nejm/medical-journal
Perspective
Beyond the Ebola Battle — Winning the War against Future Epidemics
Victor J. Dzau, M.D., and Peter Sands, M.P.A.
N Engl J Med 2016; 375:203-204 July 21, 2016 DOI: 10.1056/NEJMp1605847
[Initial text]
The battle to contain and ultimately defeat the Ebola epidemic of 2014–2015 has been vividly described.1-3 Caught off guard from the start and hindered by myriad coordination, communication, and other problems, a combination of local and international teams fought back with determination, courage, and eventually the deployment of substantial resources to stem the contagion and save lives. Yet more than 11,000 people died, and local economies were brought to a halt. The battle was won, but at immense cost.

With the immediate crisis over, the world’s attention has moved on. Ebola has vanished from the headlines and seemingly from policymakers’ to-do lists. Attention has shifted to Zika and other competing priorities. Yet it would be a huge mistake to turn away and declare the war over, for West Africa remains vulnerable to a resurgence of Ebola. There will undoubtedly be new outbreaks; the only question is how well they will be contained…

Women’s Education and Health Inequalities in Under-Five Mortality in Selected Sub-Saharan African Countries, 1990–2015

PLoS One
http://www.plosone.org/
[Accessed 23 July 2016]

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Research Article
Women’s Education and Health Inequalities in Under-Five Mortality in Selected Sub-Saharan African Countries, 1990–2015
Aristide Romaric Bado, A. Sathiya Susuman
Research Article | published 21 Jul 2016 | PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0159186
Abstract
Background
The aim of the study was to analyse trends in the relationship between mother’s educational level and mortality of children under the year of five in Sub-Saharan Africa, from 1990 to 2015.
Data and Methods
Data used in this study came from different waves of Demographic and Health Surveys (DHS) of Sub-Saharan countries. Logistic regression and Buis’s decomposition method were used to explore the effect of mother’s educational level on the mortality of children under five years.
Results
Although the results of our study in the selected countries show that under-five mortality rates of children born to mothers without formal education are higher than the mortality rates of children of educated mothers, it appears that differences in mortality were reduced over the past two decades. In selected countries for our study, we noticed a significant decline in mortality among children of non-educated mothers compared to the decrease in mortality rates among children of educated mothers during the period of 1990–2010. The results show that the decline in mortality of children under five years was much higher among the children born to mothers who have never received formal education—112 points drop in Malawi, over 80 in Zambia and Zimbabwe, 65 points in Burkina Faso, 56 in Congo, 43 in Namibia, 27 in Guinea, Cameroon, and 22 to 15 in Niger. However, we noted a variation in results among the countries selected for the study—in Burkina Faso (OR = 0.7), in Cameroon (OR = 0.8), in Guinea (OR = 0.8) and Niger (OR = 0.8). It is normally observed that children of mothers with 0–6 years of education are about 20% more likely to survive until their fifth year compared to children of mothers who have not been to school. Conversely, the results did not reveal significant differences between the under-five deaths of children born to non-educated mothers and children of low-level educated mothers in Congo, Malawi and Namibia.
Conclusion
The decline in under-five mortality rates, during last two decades, can be partly due to the government policies on women’s education. It is evident that women’s educational level has resulted in increased maternal awareness about infant health and hygiene, thereby bringing about a decline in the under-five mortality rates. This reduction is due to improved supply of health care programmes and health policies in reducing economic inequalities and increasing access to health care.

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Research Article |
Assessing Progress, Impact, and Next Steps in Rolling Out Voluntary Medical Male Circumcision for HIV Prevention in 14 Priority Countries in Eastern and Southern Africa through 2014
Katharine Kripke, Emmanuel Njeuhmeli, Julia Samuelson, Melissa Schnure, Shona Dalal, Timothy Farley, Catherine Hankins, Anne G. Thomas, Jason Reed, Peter Stegman, Naomi Bock
published 21 Jul 2016 | PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0158767

The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease

PLoS Pathogens
http://journals.plos.org/plospathogens/
(Accessed 23 July 2016)

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Pearls
The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease
Kelly J. Pittman, Luke C. Glover, Liuyang Wang, Dennis C. Ko
| published 21 Jul 2016 | PLOS Pathogens
http://dx.doi.org/10.1371/journal.ppat.1005680
[Initial text]
For millennia, pathogens and human hosts have engaged in a perpetual struggle for supremacy. From the earliest recorded smallpox epidemics around 1350 B.C.E to the Black Death due to Yersinia pestis in the Middle Ages and continuing to modern times with HIV, there has been a continuous clash between pathogens and human hosts. But past pandemics are more than just ancient history—they are drivers of human genetic diversity and natural selection. Pathogens can dramatically decrease survival and reproductive potential, leading to selection for resistance alleles and elimination of susceptibility alleles. Despite this persistent struggle between host and pathogen, only in the past century have we developed an understanding of some of the human genetic differences that regulate infectious disease susceptibility and severity…

Growth mindset tempers the effects of poverty on academic achievement

PNAS – Proceedings of the National Academy of Sciences of the United States of America
http://www.pnas.org/content/early/
(Accessed 23 July 2016)

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Social Sciences – Psychological and Cognitive Sciences:
Growth mindset tempers the effects of poverty on academic achievement
Susana Claroa,1, David Pauneskub, and Carol S. Dweckb,1
Significance
This study is the first, to our knowledge, to show that a growth mindset (the belief that intelligence is not fixed and can be developed) reliably predicts achievement across a national sample of students, including virtually all of the schools and socioeconomic strata in Chile. It also explores the relationship between income and mindset for the first time, to our knowledge, finding that students from lower-income families were less likely to hold a growth mindset than their wealthier peers but that those who did hold a growth mindset were appreciably buffered against the deleterious effects of poverty on achievement. These results suggest that mindsets may be one mechanism through which economic disadvantage can affect achievement.
Abstract
Two largely separate bodies of empirical research have shown that academic achievement is influenced by structural factors, such as socioeconomic background, and psychological factors, such as students’ beliefs about their abilities. In this research, we use a nationwide sample of high school students from Chile to investigate how these factors interact on a systemic level. Confirming prior research, we find that family income is a strong predictor of achievement. Extending prior research, we find that a growth mindset (the belief that intelligence is not fixed and can be developed) is a comparably strong predictor of achievement and that it exhibits a positive relationship with achievement across all of the socioeconomic strata in the country. Furthermore, we find that students from lower-income families were less likely to hold a growth mindset than their wealthier peers, but those who did hold a growth mindset were appreciably buffered against the deleterious effects of poverty on achievement: students in the lowest 10th percentile of family income who exhibited a growth mindset showed academic performance as high as that of fixed mindset students from the 80th income percentile. These results suggest that students’ mindsets may temper or exacerbate the effects of economic disadvantage on a systemic level.

Ecological disruption precedes mass extinction

PNAS – Proceedings of the National Academy of Sciences of the United States of America
http://www.pnas.org/content/early/
(Accessed 23 July 2016)

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Commentary
Ecological disruption precedes mass extinction
Steven M. Hollanda,1
[Initial text]
Mass extinctions are dramatic features of the fossil record in which extinction risk is substantially elevated above background levels. Although extinction risk varies markedly over geologic time, as well as geographically, it was particularly elevated and global in extent during the so-called Big Five events: the Late Ordovician, Late Devonian, end-Permian, end-Triassic, and end-Cretaceous (1). These events were originally recognized by variations in extinction rate in marine animal families, and their importance remains in analyses at the genus level and that account for variable preservation over geologic time (2, 3). Increasing attention has concentrated on understanding the ecological effects of mass extinction and other lesser but still significant extinction episodes (4⇓⇓⇓⇓⇓–10). In PNAS, Sheets et al. (11) document the ecological changes in marine planktonic communities not only during, but preceding the Late Ordovician (447–444 Ma) mass extinction.

Examining the ecological changes during a mass extinction would seem to be straightforward: go to a stratigraphic column spanning the mass extinction and describe the changing ecological composition of successive sedimentary layers through the extinction episode. This would be a direct history of ecological changes related to the extinction if those layers recorded the same habitat through time, such as the distance from shore or water depth for marine benthic organisms, or the overlying water masses for marine plankton. Unfortunately, this simple scenario is rarely the case, as numerous studies of sedimentation over the past 40 y have shown (12). Processes of sediment accumulation create two challenges for studying ancient mass extinctions (13).

Healthcare access and quality of birth care: narratives of women living with obstetric fistula in rural Tanzania

Reproductive Health
http://www.reproductive-health-journal.com/content
[Accessed 23 July 2016]
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Research
Healthcare access and quality of birth care: narratives of women living with obstetric fistula in rural Tanzania
Increasing births with skilled attendants and increasing health facilities with Emergency Obstetric Care (EmOC) can reduce maternal mortality and are considered critical interventions for ensuring safe motherh…
Lilian T. Mselle and Thecla W. Kohi
Reproductive Health 2016 13:87
Published on: 22 July 2016

Special Issue: Strengthening of Regulatory Systems for Medicines in the Americas

Revista Panamericana de Salud Pública/Pan American Journal of Public Health (RPSP/PAJPH)
June 2016
http://www.paho.org/journal/

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Special Issue: Strengthening of Regulatory Systems for Medicines in the Americas
Health regulation is regarded as one of public health’s basic functions. Effective regulation of medicines promotes and protects the public’s health by guaranteeing medicines quality, safety, and efficacy; promoting the adequate manufacture, storage, and distribution of medicines; facilitating the fight against substandard, spurious, falsely-labeled, falsified, or counterfeit (SSFFC) medical products; providing the necessary information to health professionals and patients so they can use medicines rationally; and ensuring that access to medicines is not hindered by inefficient regulatory frameworks. Developing a national regulatory system is, hence, a critical component of a national health system.
This special issue of the Pan American Journal of Public Health was a joint project supported by the US Food and Drug Administration. The issue comprises 14 original peer reviewed research articles that highlight the progress and remaining challenges that the Region faces in ensuring access to safe, efficacious and quality-assured medical products.
[Series of articles]

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Strengthening of regulatory systems for medicines in the Americas
Etienne, Carissa F. Califf, Robert
Abstract
Health regulation is regarded as one of public health’s basic functions. Effective regulation of medicines promotes and protects the public’s health by guaranteeing medicines quality, safety, and efficacy; promoting the adequate manufacture, storage, and distribution of medicines; facilitating the fight against substandard, spurious, falsely labeled, falsified, or counterfeit medical products; providing the necessary information to health professionals and patients so they can use medicines rationally; and ensuring that access to medicines is not hindered by inefficient regulatory frameworks. Developing a strong national regulatory system is, therefore, a critical component of a national health system. In this context, we are pleased to present the first ever special issue of the Pan American Journal of Public Health to focus on strengthening of regulatory systems for medicines and other technologies. This special issue is an expression of the resolve of the governments of the Americas in implementing the Pan American Health Organization Directing Council Resolution CD50.R9 (2010) “Strengthening National Regulatory Authorities for Medicines and Biologicals,” and more recently of the Member States of the World Health Organization in the adoption of resolution WHA67.20 (2014), “Regulatory system strengthening for medical products.”…The journal brings together articles from regulatory experts within the Region of the Americas as well as from global experts, who bring an array of experiences to the fore. They present the essential underpinning of science and regulation that bring life-saving and innovative products to the marketplace; analysis of key contributions from international fora and public-private coalitions that can add to regulatory science and the development of good regulatory practices; and the ever-evolving challenges that regulators face to build inter-linked and convergent regulatory systems within the context of limited capacity, human and financial resources, nationally and globally.