Save The Children [to 20 February 2016]

Save The Children [to 20 February 2016]
http://www.savethechildren.org/site/c.8rKLIXMGIpI4E/b.9357111/k.C14B/Press_Releases_2016/apps/nl/newsletter2.asp

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February 16, 2016
Statement from Carolyn Miles on Yesterday’s Attacks on Seven Healthcare Facilities in Syria

Fairfield, Conn. (February 16, 2015) — In response to yesterday’s attacks on healthcare facilities in Syria, Carolyn Miles, President & CEO of Save the Children U.S. says: “Save the Children is appalled by the growing trend for health facilities, schools and other civilian infrastructure to be the targets of deadly attacks in Syria.

“Monday was the worst day for attacks on healthcare facilities for more than six months. New information gathered by Save the Children and other organizations suggests that in total, seven facilities were bombed in air strikes, more than was first reported. The attacks happened across Syria, in Aleppo, Idlib and Dara’a provinces…

SOS-Kinderdorf International [to 20 February 2016]

SOS-Kinderdorf International [to 20 February 2016]
http://www.sos-childrensvillages.org/about-sos/press/press-releases

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19.02.2016
Ukraine: Children sketch a future without war
– An exhibition of drawings from talented and vulnerable children living on both sides of the conflict in the Lugansk and Donetsk regions was recently organised by SOS Children’s Villages Ukraine in partnership with Swiss Embassy and the Maximal youth organisation in Donetsk.

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18.02.2016
SOS Children’s Villages International announces changes to top management team
INNSBRUCK, Austria – SOS Children’s Villages International has announced that Richard Pichler, who served as Secretary General and CEO for more than 20 years, will assume a new role in the organisation as of May 2016. Mr Pichler will take on the newly created position of Special Representative for External Affairs and Resources, in which he will focus on high level external relations and partnerships. The International Senate expressed its appreciation for the achievements of Mr Pichler during his tenure as Secretary General and CEO, and is very much looking forward to continue the cooperation with him.

SOS Children’s Villages’ new global strategy – expected to be confirmed at its General Assembly in June – calls for the federation to work more closely with partners in civil society, global foundations, international forums and multilateral organisations, as well as to raise the global profile of the organisation, thus increasing the organisation’s impact for children. To deliver this step change, Richard Pichler will take on this challenging task. In recent years, he has successfully led the organisation to increase its engagement on the international stage in efforts such as contributing to the UN Sustainable Development Goals and the UN Guidelines for the Alternative Care of Children, and forging closer ties with the other child-focused INGOs.

Until a new CEO joins, management responsibilities will be collectively shared by the Management Team: CFO Norbert Meder, COO Carsten Völz, and Tom Malvet, Director of International Competence Centres.

SOS Children’s Villages International President Siddhartha Kaul expressed his appreciation of Mr Pichler: “Richard Pichler has done exceptional work for SOS Children’s Villages International as its Secretary General and CEO for over 20 years. In his new role, Richard will continue to have a profound impact on our work by serving as one of the key voices of SOS Children’s Villages on the international stage. We know he will be a passionate spokesman and advocate for our organisation and give a voice to the needs of vulnerable children.”

Mr Pichler said: “It has been both exciting and humbling to be part of the organisation’s journey on this rapid development until now. I thank all colleagues who supported me along that way. In recent times it has become evident that we can increase our impact by partnering and by developing a stronger global positioning of our organisation. In the past, as CEO, I could initiate some developments. After 20 years in daily management I now look forward to fully concentrating on partnerships and positioning for the benefit of the most vulnerable children. I am convinced together we can increase our impact.”

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17.02.2016
Measuring impact
– With the help of a major global management consultancy, SOS Children’s Villages has developed a system for measuring how a donor’s contribution translates into improving children’s lives.

Tostan [to 20 February 2016]

Tostan [to 20 February 2016]
http://www.tostan.org/latest-news

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February 17, 2016
Malian Communities Take Abandoning Harmful Practices Into Their Own Hands
In southwestern Mali, a small, but powerful movement is growing. In 2014, 40 Malian communities started Tostan’s Community Empowerment Program …

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February 16, 2016
Youth Voices: The Next Generation of Changemakers in West Africa
The latest film in our Breakthrough Generation series, “Youth Voices: The Next Generation of Changemakers in West Africa,” follows young people who came together in December …

ChildFund Alliance [to 20 February 2016]

ChildFund Alliance [to 20 February 2016]
http://childfundalliance.org/news/

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[undated]
ChildFund supporting European refugees
Author: Avril MacDonald
ChildFund Alliance is supporting children and families on their way to Europe from countries such as Syria, Afghanistan and Iraq. Next to the border controls in Macedonia and Serbia, contemporary aid stations have been constructed where people can stop to receive medical support, warm clothes and food. In cooperation with Terre des Hommes, ChildFund is supporting a local partner, providing children and families with friendly spaces and psychosocial support. In the child friendly spaces children can play and parents can change their babies’ diapers and receive counselling in both practical matters, and how they can protect their children from danger such as getting lost along the road…

The Elders [to 20 February 2016]

The Elders [to 20 February 2016]
http://theelders.org/news-media

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News 15 February 2016
The Elders statement on the death of Boutros Boutros-Ghali (1922-2016)
The Elders extend their deepest condolences to the family of Boutros Boutros-Ghali, former UN Secretary-General.

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News Lakhdar Brahimi 15 February 2016
Syria: time to put an immediate halt to all the fighting
As the violence engulfing Syria continues, veteran mediator and former UN Special Envoy to Syria Lakhdar Brahimi calls on all parties to end the violence, prioritise the needs of the Syrian people and for European governments to agree a coordinated response to the refugee crisis.

Global Fund [to 20 February 2016]

Global Fund [to 20 February 2016]
http://www.theglobalfund.org/en/news/

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17 February 2016
Organization of Islamic Cooperation and the Global Fund Strengthen Partnership
JEDDAH, Saudi Arabia – The Secretary General of the Organization of the Islamic Conference (OIC), Iyad Ameen Madani, praised the support that the Global Fund extends to the member states of the OIC.
At a meeting with senior representatives of the Global Fund on 16 February, the Secretary General stressed that the OIC will continue to support the Global Fund’s efforts…

…The Global Fund is a major supporter of health efforts in OIC member states. Today, 50 of the 57 OIC member states are implementing programs supported by the Global Fund to fight diseases and build resilient and sustainable systems for health.

With US$11.3 billion signed in grants, 2.7 million people are currently receiving treatment for HIV, 5.3 million cases of TB have been detected and treated, 320 million mosquito nets have been distributed to prevent malaria and 1.6 million orphans and vulnerable children are receiving basic care and support services.

Hilton Prize Coalition [to 20 February 2016]

Hilton Prize Coalition [to 20 February 2016]
http://prizecoalition.charity.org/
An Alliance of Hilton Prize Recipients

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Part 2 of the Storytelling Series in Nepal: Crew
Posted February 18, 2016 ·
Photojournalist and documentary filmmaker Steve Connors serves as the Master Storyteller for the Hilton Prize Coalition Storytelling Program. He is traveling throughout Nepal this month to capture the experiences of the six Coalition member organizations who mobilized in response to the devastating earthquakes of 2015 – and share stories about their staff and personnel, the individuals […]

Center for Global Development [to 20 February 2016]

Center for Global Development [to 20 February 2016]
http://www.cgdev.org/page/press-center
Selected Press Releases, Blog Posts, Publications

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Middle-Class Heroes: The Best Guarantee of Good Governance
2/16/16
Nancy Birdsall
The two economic developments that have garnered the most attention in recent years are the concentration of massive wealth in the richest one percent of the world’s population and the tremendous, growth-driven decline in extreme poverty in the developing world, especially in China. But just as important has been the emergence of large middle classes in developing countries around the planet. This phenomenon—the result of more than two decades of nearly continuous fast-paced global economic growth—has been good not only for economies but also for governance. After all, history suggests that a large and secure middle class is a solid foundation on which to build and sustain an effective, democratic state. Middle classes not only have the wherewithal to finance vital services such as roads and public education through taxes; they also demand regulations, the fair enforcement of contracts, and the rule of law more generally—public goods that create a level social and economic playing field on which all can prosper.

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Next Generation Financing for Global Health: What, Why, When, How?
2/16/16
Amanda Glassman and Rachel Silverman
Many researchers and policymakers have hypothesized that funding models tying grant payments to achieved and verified results — next generation financing models — offer an opportunity for global health funders to push forward their strategic interests and accelerate the impact of their investments. This brief, summarizing the conclusions of a CGD working group on the topic, outlines concrete steps global health funders can take to change the basis of payment of their grants from expenses (inputs) to outputs, outcomes, or impact.

ODI [to 20 February 2016]

ODI [to 20 February 2016]
http://www.odi.org/media

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News | 17 February 2016
Anti-migration policies do not stop people making the decision to migrate to Europe – new report
New research from the Overseas Development Institute suggests European anti-migration policies have limited impact on a migrant’s decision to embark on dangerous, lengthy and expensive journeys in search of a better life

Budget support to Uganda 1998-2012: a review
Briefing papers | February 2016 | Tim Williamson, Fiona Davies, Imran Aziz, Edward Hedger
This paper provides a critical appraisal of the suspended budget support programme in Uganda, highlighting important lessons for the donor community.

Climate resilience and financial services
Working and discussion papers | February 2016 | Anna Haworth, Camille Frandon-Martinez, Virginie Fayolle and Catherine Simonet
This BRACED working paper provides a high-level overview of the context and structure of the financial services sector in three BRACED countries; Ethiopia, Mali and Myanmar.

The political economy of voter engagement in Niger
Research reports and studies | February 2016 | Aoife McCullough, Abdoutan Harouna and Hamani Oumarou with Yaye Djingarey Zaratou Idi Mamadou, Maman Noura, Sadjo Aissa and Abdouramane Magagi Kabo
Based on research carried out in three regions of Niger, this briefing explores how political parties and candidates engage with Nigerien voters.

Collective action and the deployment of teachers in Niger: a political economy analysis
Research reports and studies | February 2016 | Clare Cummings and Ali Bako M. Tahirou with Hamissou Rhissa, Falmata Hamed, Hamadou Goumey, and Idi Mahamadou Mamane Noura
This briefing paper explores causes of inequitable teacher deployment in Niger and asks whether collective action might be the solution.

What is impact?
Working and discussion papers | February 2016 | Simon Hearn and Anne Buffardi
How ‘impact’ is defined and used has a significant effect on the design, management and evaluation of development programmes.

Aga Khan Foundation [to 20 February 2016]

Aga Khan Foundation [to 20 February 2016]
http://www.akdn.org/pr.asp

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12 February 2016
Reducing Risk and Preparing Communities for Disasters in Tajikistan and Kyrgyzstan Republics of Central Asia
– Hazard Vulnerability and Risk Assessments (HVRAs) have been completed in 339 villages in GBAO and Naryn town, reaching approximately 400,000 individuals and 139 organizations, through the DIPECHO project “Fostering Disaster Resilient Communities in Isolated Mountain Environments”…

…The eighth phase of the project has been successfully completed, which stems from an agreement between the European Commission’s Humanitarian Aid Department (ECHO) under the auspices of its Disaster Preparedness Program (DIPECHO) and Aga Khan Foundation (AKF) United Kingdom. The ninth phase of the project is due to commence in February 2016.

FOCUS, MSDSP and AKF through the DIPECHO project reduces risk, develops sustainable solutions and promotes widespread systemic changes in risk reduction policy making at the local and national levels in Tajikistan and Kyrgyzstan. Strengthening the capacity of Disaster Risk Management (DRM) and educational institutions increases the ability to assess and prepare for natural hazards and to respond more effectively to emergencies.

Conrad N. Hilton Foundation [to 20 February 2016]

Conrad N. Hilton Foundation [to 20 February 2016]
http://www.hiltonfoundation.org/news

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New Release
Continuing our Commitment to Ending Homelessness: Board Approves Phase II of Strategic Initiative
By Andrea Iloulian, February 17, 2016

Over the past 25 years, the Conrad N. Hilton Foundation has supported efforts to end long-term homelessness across the nation. We have sought to advance compassionate and cost-effective solutions to homelessness, awarding more than $90 million in grants—primarily by advancing the permanent supportive housing model since 1990.

At the close of 2015, our board approved the second phase of our strategy—an additional five-year commitment to begin in January 2016…

MacArthur Foundation [to 20 February 2016]

MacArthur Foundation [to 20 February 2016]
http://www.macfound.org/

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Publication
Fewer Women Ages 65 and Over Living Alone
Published February 18, 2016
A report by the Pew Research Center, conducted in partnership with the MacArthur Foundation Research Network on an Aging Society, finds the share of older Americans who live alone has fallen 3% since 1990, largely because women ages 65 to 84 are increasingly likely to live with their spouse or their children. The report attributes this trend to an increase in life expectancy, especially among men, which has made it more likely that older women would be living with their spouses rather than as widows.

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Publication
$18M in Grants to Advance Public Interest Technology
Published February 16, 2016
In a joint commitment to uncover new ways the Internet can be used to foster learning and promote justice, MacArthur and the Ford, Knight, Open Society, and Mozilla foundations have committed a combined $18M in grants to strengthen the emerging field of public interest technology. The grants will support a range of initiatives from fellowships that bring technology into journalism, science, and public policy, to a program that partners with civil society and government organizations to explore how technologies impact civil liberties, civil rights, and consumer protection matters. The NetGain partners also released their first report detailing opportunities and best practices for others to join the movement to build and expand public interest technology.

Pew Charitable Trusts [to 20 February 2016]

Pew Charitable Trusts [to 20 February 2016]
http://www.pewtrusts.org/en/about/news-room/press-releases

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Statement
Pew Applauds Designation of National Monuments in California Desert
‘Momentous action’ protects the Mojave Trails, Sand to Snow, and Castle Mountains regions
February 12, 2016
Note: On Feb. 12, 2016, President Barack Obama designated three new national monuments in the California desert, encompassing nearly 1.8 million acres.
WASHINGTON—The Pew Charitable Trusts today praised the Obama administration’s designation of three new national monuments in the California desert: Mojave Trails, along historic Route 66 between Needles and Barstow; Sand to Snow, northwest of Palm Springs; and Castle Mountains, on the Nevada border south of Las Vegas. Mojave Trails is the largest land monument designated by President Barack Obama.

Mike Matz, director of Pew’s U.S. public lands program, released the following statement:
“President Obama’s designation of the most expansive national monuments of his administration is a momentous action with positive implications for local economies, threatened historic and cultural areas, and migrating wildlife. We applaud the president’s thoughtful use of authority granted to him by Congress under the Antiquities Act to safeguard Mojave Trails, Sand to Snow, and Castle Mountains…

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Opinion
The Transparency That Public Pensions Need
Pension investments are increasingly complex, but disclosure standards have not kept pace
February 16, 2016

Ethical Rationale for the Ebola “Ring Vaccination” Trial Design

American Journal of Public Health
Volume 106, Issue 3 (March 2016)
http://ajph.aphapublications.org/toc/ajph/current

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AJPH LAW & ETHICS
EBOLA VACCINE
Ethical Rationale for the Ebola “Ring Vaccination” Trial Design
Annette Rid, Franklin G. Miller
American Journal of Public Health: March 2016, Vol. 106, No. 3: 432–435.
Abstract |
The 2014 Ebola virus epidemic is the largest and most severe ever recorded. With no approved vaccines or specific treatments for Ebola, clinical trials were launched within months of the epidemic in an unprecedented show of global partnership. One of these trials used a highly innovative “ring vaccination” design. The design was chosen for operational, scientific, and ethical reasons—in particular, it was regarded as ethically superior to individually randomized placebo-controlled trials.

We scrutinize the ethical rationale for the ring vaccination design. We argue that the ring vaccination design is ethical but fundamentally equivalent to placebo-controlled designs with respect to withholding a potentially effective intervention from the control group.
We discuss the implications for the ongoing ring vaccination trial and future research.

BMC Health Services Research (Accessed 20 February 2016)

BMC Health Services Research
http://www.biomedcentral.com/bmchealthservres/content
(Accessed 20 February 2016)

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Research article
Evaluating a complex model designed to increase access to high quality primary mental health care for under-served groups: a multi-method study
Christopher Dowrick, Peter Bower, Carolyn Chew-Graham, Karina Lovell, Suzanne Edwards, Jonathan Lamb, Katie Bristow, Mark Gabbay, Heather Burroughs, Susan Beatty, Waquas Waheed, Mark Hann and Linda Gask
BMC Health Services Research 2016 16:58
Published on: 17 February 2016
Abstract
Background
Many people with mental distress are disadvantaged because care is not available or does not address their needs. In order to increase access to high quality primary mental health care for under-served groups, we created a model of care with three discrete elements: community engagement, primary care training and tailored wellbeing interventions. We have previously demonstrated the individual impact of each element of the model. Here we assess the effectiveness of the combined model in increasing access to and improving the quality of primary mental health care. We test the assumptions that access to the wellbeing interventions is increased by the presence of community engagement and primary care training; and that quality of primary mental health care is increased by the presence of community engagement and the wellbeing interventions.
Methods
We implemented the model in four under-served localities in North-West England, focusing on older people and minority ethnic populations. Using a quasi-experimental design with no-intervention comparators, we gathered a combination of quantitative and qualitative information. Quantitative information, including referral and recruitment rates for the wellbeing interventions, and practice referrals to mental health services, was analysed descriptively. Qualitative information derived from interview and focus group responses to topic guides from more than 110 participants. Framework analysis was used to generate findings from the qualitative data.
Results
Access to the wellbeing interventions was associated with the presence of the community engagement and the primary care training elements. Referrals to the wellbeing interventions were associated with community engagement, while recruitment was associated with primary care training. Qualitative data suggested that the mechanisms underlying these associations were increased awareness and sense of agency. The quality of primary mental health care was enhanced by information gained from our community mapping activities, and by the offer of access to the wellbeing interventions. There were variable benefits from health practitioner participation in community consultative groups. We also found that participation in the wellbeing interventions led to increased community engagement.
Conclusions
We explored the interactions between elements of a multilevel intervention and identified important associations and underlying mechanisms. Further research is needed to test the generalisability of the model.
Trial registration
Current Controlled Trials, reference ISRCTN68572159. Registered 25 February 2013.

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Research article
Maternal mental health in primary care in five low- and middle-income countries: a situational analysis
Emily C. Baron, Charlotte Hanlon, Sumaya Mall, Simone Honikman, Erica Breuer, Tasneem Kathree, Nagendra P. Luitel, Juliet Nakku, Crick Lund, Girmay Medhin, Vikram Patel, Inge Petersen, Sanjay Shrivastava and Mark Tomlinson
BMC Health Services Research 2016 16:53
Published on: 16 February 2016
Abstract
Background
The integration of maternal mental health into primary health care has been advocated to reduce the mental health treatment gap in low- and middle-income countries (LMICs). This study reports findings of a cross-country situation analysis on maternal mental health and services available in five LMICs, to inform the development of integrated maternal mental health services integrated into primary health care.
Methods
The situation analysis was conducted in five districts in Ethiopia, India, Nepal, South Africa and Uganda, as part of the Programme for Improving Mental Health Care (PRIME). The analysis reports secondary data on the prevalence and impact of priority maternal mental disorders (perinatal depression, alcohol use disorders during pregnancy and puerperal psychosis), existing policies, plans and services for maternal mental health, and other relevant contextual factors, such as explanatory models for mental illness.
Results
Limited data were available at the district level, although generalizable data from other sites was identified in most cases. Community and facility-based prevalences ranged widely across PRIME countries for perinatal depression (3–50 %) and alcohol consumption during pregnancy (5–51 %). Maternal mental health was included in mental health policies in South Africa, India and Ethiopia, and a mental health care plan was in the process of being implemented in South Africa. No district reported dedicated maternal mental health services, but referrals to specialised care in psychiatric units or general hospitals were possible. No information was available on coverage for maternal mental health care. Challenges to the provision of maternal mental health care included; limited evidence on feasible detection and treatment strategies for maternal mental disorders, lack of mental health specialists in the public health sector, lack of prescribing guidelines for pregnant and breastfeeding women, and stigmatising attitudes among primary health care staff and the community.
Conclusions
It is difficult to anticipate demand for mental health care at district level in the five countries, given the lack of evidence on the prevalence and treatment coverage of women with maternal mental disorders. Limited evidence on effective psychosocial interventions was also noted, and must be addressed for mental health programmes, such as PRIME, to implement feasible and effective services.

BMC Public Health (Accessed 20 February 2016)

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 20 February 2016)

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Research article
Factors influencing completion of multi-dose vaccine schedules in adolescents: a systematic review
K. E. Gallagher, E. Kadokura, L. O. Eckert, S. Miyake, S. Mounier-Jack, M. Aldea, D. A. Ross and D. Watson-Jones
BMC Public Health 2016 16:172
Published on: 19 February 2016
Abstract
Background
Completion of multiple dose vaccine schedules is crucial to ensure a protective immune response, and maximise vaccine cost-effectiveness. While barriers and facilitators to vaccine uptake have recently been reviewed, there is no comprehensive review of factors influencing subsequent adherence or completion, which is key to achieving vaccine effectiveness. This study identifies and summarises the literature on factors affecting completion of multi-dose vaccine schedules by adolescents.
Methods
Ten online databases and four websites were searched (February 2014). Studies with analysis of factors predicting completion of multi-dose vaccines were included. Study participants within 9–19 years of age were included in the review. The defined outcome was completion of the vaccine series within 1 year among those who received the first dose.
Results
Overall, 6159 abstracts were screened, and 502 full texts were reviewed. Sixty one studies were eligible for this review. All except two were set in high-income countries. Included studies evaluated human papillomavirus vaccine, hepatitis A, hepatitis B, and varicella vaccines. Reported vaccine completion rates, among those who initiated vaccination, ranged from 27 % to over 90 %. Minority racial or ethnic groups and inadequate health insurance coverage were risk factors for low completion, irrespective of initiation rates. Parental healthcare seeking behaviour was positively associated with completion. Vaccine delivery in schools was associated with higher completion than delivery in the community or health facilities. Gender, prior healthcare use and socio-economic status rarely remained significant risks or protective factors in multivariate analysis.
Conclusions
Almost all studies investigating factors affecting completion have been carried out in developed countries and investigate a limited range of variables. Increased understanding of barriers to completion in adolescents will be invaluable to future new vaccine introductions and the further development of an adolescent health platform.
PROSPERO reg# CRD42014006765.

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Research article
Reducing routine vaccination dropout rates: evaluating two interventions in three Kenyan districts, 2014
Adam Haji, S. Lowther, Z. Ngan’ga, Z. Gura, C. Tabu, H. Sandhu and Wences Arvelo
BMC Public Health 2016 16:152
Published on: 16 February 2016
Abstract
Background
Globally, vaccine preventable diseases are responsible for nearly 20 % of deaths annually among children <5 years old. Worldwide, many children dropout from the vaccination program, are vaccinated late, or incompletely vaccinated. We evaluated the impact of text messaging and sticker reminders to reduce dropouts from the vaccination program.
Methods
The evaluation was conducted in three selected districts in Kenya: Machakos, Langata and Njoro. Three health facilities were selected in each district, and randomly allocated to send text messages or provide stickers reminding parents to bring their children for second and third dose of pentavalent vaccine, or to the control group (routine reminder) with next appointment date indicated on the well-child booklet. Children aged <12 months presenting for their first dose of pentavalent vaccine were enrolled. A dropout was defined as not returning for vaccination ≥2 weeks after scheduled date for third dose of pentavalent vaccine. We calculated dropout rate as a percentage of the difference between first and third pentavalent dose.
Results
We enrolled 1,116 children; 372 in each intervention and 372 controls between February and October 2014. Median age was 45 days old (range: 31–99 days), and 574 (51 %) were male. There were 136 (12 %) dropouts. Thirteen (4 %) children dropped out among those who received text messages, 60 (16 %) among who received sticker reminders, and 63 (17 %) among the controls. Having a caregiver with below secondary education [Odds Ratio (OR) 1.8, 95 % Confidence Interval (CI) 1.1–3.2], and residing >5 km from health facility (OR 1.6, CI 1.0–2.7) were associated with higher odds of dropping out. Those who received text messages were less likely to drop out compared to controls (OR 0.2, CI 0.04–0.8). There was no statistical difference between those who received stickers and controls (OR 0.9, CI 0.5–1.6).
Conclusion
Text message reminders can reduce vaccination dropout rates in Kenya. We recommend the extended implementation of text message reminders in routine vaccination services.

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Research article
The first mile: community experience of outbreak control during an Ebola outbreak in Luwero District, Uganda
A major challenge to outbreak control lies in early detection of viral haemorrhagic fevers (VHFs) in local community contexts during the critical initial stages of an epidemic, when risk of spreading is its highest…
Daniel H. de Vries, Jude T. Rwemisisi, Laban K. Musinguzi, Turinawe E. Benoni, Denis Muhangi, Marije de Groot, David Kaawa-Mafigiri and Robert Pool
BMC Public Health 2016 16:161
Published on: 16 February 2016

The economic burden of childhood pneumococcal diseases in The Gambia

BMC Cost Effectiveness and Resource Allocation
http://resource-allocation.biomedcentral.com/
(Accessed 20 February 2016)

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Research
The economic burden of childhood pneumococcal diseases in The Gambia
Effua Usuf, Grant Mackenzie, Sana Sambou, Deborah Atherly and Chutima Suraratdecha
Published on: 17 February 2016
Abstract
Background
Streptococcus pneumoniae is a common cause of child death. However, the economic burden of pneumococcal disease in low-income countries is poorly described. We aimed to estimate from a societal perspective, the costs incurred by health providers and families of children with pneumococcal diseases.
Methods
We recruited children less than 5 years of age with outpatient pneumonia, inpatient pneumonia, pneumococcal sepsis and bacterial meningitis at facilities in rural and urban Gambia. We collected provider costs, out of pocket costs and productivity loss for the families of children. For each disease diagnostic category, costs were collected before, during, and for 1 week after discharge from hospital or outpatient visit.
Results
A total of 340 children were enrolled; 100 outpatient pneumonia, 175 inpatient pneumonia 36 pneumococcal sepsis, and 29 bacterial meningitis cases. The mean provider costs per patient for treating outpatient pneumonia, inpatient pneumonia, pneumococcal sepsis and meningitis were US$8, US$64, US$87 and US$124 respectively and the mean out of pocket costs per patient were US$6, US$31, US$44 and US$34 respectively. The economic burden of outpatient pneumonia, inpatient pneumonia, pneumococcal sepsis and meningitis increased to US$15, US$109, US$144 and US$170 respectively when family members’ time loss from work was taken into account.
Conclusion
The economic burden of pneumococcal disease in The Gambia is substantial, costs to families was approximately one-third to a half of the provider costs, and accounted for up to 30 % of total societal costs. The introduction of pneumococcal conjugate vaccine has the potential to significantly reduce this economic burden in this society.

Publication and reporting of clinical trial results: cross sectional analysis across academic medical centers

British Medical Journal
20 February 2016 (vol 352, issue 8045)
http://www.bmj.com/content/352/8045

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Research Update
Publication and reporting of clinical trial results: cross sectional analysis across academic medical centers
BMJ 2016; 352 :i637 (Published 17 February 2016)
Abstract
Objective
To determine rates of publication and reporting of results within two years for all completed clinical trials registered in ClinicalTrials.gov across leading academic medical centers in the United States.
Design
Cross sectional analysis.
Setting
Academic medical centers in the United States.
Participants
Academic medical centers with 40 or more completed interventional trials registered on ClinicalTrials.gov.
Methods
Using the Aggregate Analysis of ClinicalTrials.gov database and manual review, we identified all interventional clinical trials registered on ClinicalTrials.gov with a primary completion date between October 2007 and September 2010 and with a lead investigator affiliated with an academic medical center.
Main outcome measures
The proportion of trials that disseminated results, defined as publication or reporting of results on ClinicalTrials.gov, overall and within 24 months of study completion.
Results
We identified 4347 interventional clinical trials across 51 academic medical centers. Among the trials, 1005 (23%) enrolled more than 100 patients, 1216 (28%) were double blind, and 2169 (50%) were phase II through IV. Overall, academic medical centers disseminated results for 2892 (66%) trials, with 1560 (35.9%) achieving this within 24 months of study completion. The proportion of clinical trials with results disseminated within 24 months of study completion ranged from 16.2% (6/37) to 55.3% (57/103) across academic medical centers. The proportion of clinical trials published within 24 months of study completion ranged from 10.8% (4/37) to 40.3% (31/77) across academic medical centers, whereas results reporting on ClinicalTrials.gov ranged from 1.6% (2/122) to 40.7% (72/177).
Conclusions
Despite the ethical mandate and expressed values and mission of academic institutions, there is poor performance and noticeable variation in the dissemination of clinical trial results across leading academic medical centers.

The 10 largest public and philanthropic funders of health research in the world: what they fund and how they distribute their funds

Health Research Policy and Systems
http://www.health-policy-systems.com/content
[Accessed 20 February 2016]

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Research
The 10 largest public and philanthropic funders of health research in the world: what they fund and how they distribute their funds
Roderik F. Viergever and Thom C. C. Hendriks
Published on: 18 February 2016
Abstract
Background
Little is known about who the main public and philanthropic funders of health research are globally, what they fund and how they decide what gets funded. This study aims to identify the 10 largest public and philanthropic health research funding organizations in the world, to report on what they fund, and on how they distribute their funds.
Methods
The world’s key health research funding organizations were identified through a search strategy aimed at identifying different types of funding organizations. Organizations were ranked by their reported total annual health research expenditures. For the 10 largest funding organizations, data were collected on (1) funding amounts allocated towards 20 health areas, and (2) schemes employed for distributing funding (intramural/extramural, project/‘people’/organizational and targeted/untargeted funding). Data collection consisted of a review of reports and websites and interviews with representatives of funding organizations. Data collection was challenging; data were often not reported or reported using different classification systems.
Results
Overall, 55 key health research funding organizations were identified. The 10 largest funding organizations together funded research for $37.1 billion, constituting 40% of all public and philanthropic health research spending globally. The largest funder was the United States National Institutes of Health ($26.1 billion), followed by the European Commission ($3.7 billion), and the United Kingdom Medical Research Council ($1.3 billion). The largest philanthropic funder was the Wellcome Trust ($909.1 million), the largest funder of health research through official development assistance was USAID ($186.4 million), and the largest multilateral funder was the World Health Organization ($135.0 million). Funding distribution mechanisms and funding patterns varied substantially between the 10 largest funders.
Conclusions
There is a need for increased transparency about who the main funders of health research are globally, what they fund and how they decide on what gets funded, and for improving the evidence base for various funding models. Data on organizations’ funding patterns and funding distribution mechanisms are often not available, and when they are, they are reported using different classification systems. To start increasing transparency in health research funding, we have established http://www.healthresearchfunders.org that lists health research funding organizations worldwide and their health research expenditures.

Methods to estimate maternal mortality: a global perspective

Journal of Epidemiology & Community Health
March 2016, Volume 70, Issue 3
http://jech.bmj.com/content/current

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Editorial
Methods to estimate maternal mortality: a global perspective
Serena Donati, Alice Maraschini, Marta Buoncristiano, the Regional Maternal Mortality Working Group
Author Affiliations
National Centre for Epidemiology, Surveillance, and Health Promotion—Istituto Superiore di Sanità, Italian National Institute of Health, Rome Italy
Extract
The maternal mortality ratio (MMR) is globally a reproductive health core indicator, and the death of a woman, while pregnant or within 42 days of termination of pregnancy, is always, anywhere and anyway, a tragedy for the entire community. Reducing the MMR is one of the Millennium Development Goals and the UN Global strategy for women’s and children’s health mobilised multiple resources and commitments to accelerate this objective.1 However MMR estimates and accurate identification of the causes of maternal death are still a complex and difficult challenge. In most developing country settings, owing to the lack of complete and accurate civil registration systems, MMR estimates are based on data from a variety of alternative sources including censuses, household surveys, reproductive age mortality studies and verbal autopsies.2 The WHO classified 183 countries/territories according to the availability and quality of maternal mortality data: 67 countries (covering 17% of births) having complete civil registration data with good attribution of causes of death, 96 countries (covering 81% of births) having incomplete civil registration and/or other types of maternal mortality data and 20 countries (covering 2% of births) lacking national data on maternal mortality. For the last two categories, a regression model has been developed to estimate maternal mortality figures.3 The Demographic and Health Surveys Program4 uses the sisterhood method for Maternal Mortality estimations. This method remains the major source of empirical data on maternal mortality in developing countries, although it presents notable limitations.