World Bank Group Launches Groundbreaking Financing Facility to Protect Poorest Countries against Pandemics

World Bank Group Launches Groundbreaking Financing Facility to Protect Poorest Countries against Pandemics
May 21, 2016 – PRESS RELEASE
First-ever insurance and pandemic bonds will save lives and protect economies

SENDAI, Japan, May 21, 2016—The World Bank Group today launched the Pandemic Emergency Financing Facility (PEF), an innovative, fast-disbursing global financing mechanism designed to protect the world against deadly pandemics, which will create the first-ever insurance market for pandemic risk. Japan, which holds the G7 Presidency, committed the first $50 million in funding toward the new initiative.

“Pandemics pose some of the biggest threats in the world to people’s lives and to economies, and for the first time we will have a system that can move funding and teams of experts to the sites of outbreaks before they spin out of control,” said Jim Yong Kim, President of the World Bank Group. “This facility addresses a long, collective failure in dealing with pandemics. The Ebola crisis in Guinea, Liberia and Sierra Leone taught all of us that we must be much more vigilant to outbreaks and respond immediately to save lives and also to protect economic growth.”…

…The new facility will accelerate both global and national responses to future outbreaks with pandemic potential. It was built and designed in collaboration with the World Health Organization and the private sector, introducing a new level of rigor into both the financing and the response.

“Recent years have seen a dramatic resurgence of the threat from emerging and re-emerging infectious diseases,” said Margaret Chan, Director-General of the World Health Organization. “WHO fully supports the Pandemic Emergency Financing Facility as a critical contribution to global health security and a crucial line of defence against high-threat pathogens.”

The PEF includes an insurance window, which combines funding from the reinsurance markets with the proceeds of World Bank-issued pandemic (catastrophe, or Cat) bonds, as well as a complementary cash window. This will be the first time World Bank Cat Bonds have been used to combat infectious diseases. In the event of an outbreak, the PEF will release funds quickly to countries and qualified international responding agencies.

The insurance window will provide coverage up to $500 million for an initial period of three years for outbreaks of infectious diseases most likely to cause major epidemics, including new Orthomyxoviruses (e.g. new influenza pandemic virus A, B and C), Coronaviridae (e.g. SARS, MERS), Filoviridae (e.g. Ebola, Marburg) and other zoonotic diseases (e.g. Crimean Congo, Rift Valley, Lassa fever). Parametric triggers designed with publicly available data will determine when the money would be released, based on the size, severity and spread of the outbreak.

The complementary cash window will provide more flexible funding to address a larger set of emerging pathogens, which may not yet meet the activation criteria for the insurance window.
All 77 countries eligible for financing from the International Development Association, the World Bank Group’s fund for the poorest countries, will be eligible to receive coverage from the PEF. The PEF is expected to be operational later this year…

…Four global expert panels that were convened over the past year in the wake of the Ebola crisis concluded that the world must urgently step up its capacity for a swift response to outbreaks before they become more deadly and costly pandemics.

The PEF will do a number of important things to prevent another Ebola crisis:
:: It will insure the world’s poorest countries against the threat of a pandemic.
:: In the event of a severe infectious disease outbreak, it will release funds quickly to the countries and/or to international responders, to accelerate the response—saving lives and reducing human suffering.
:: By mobilizing an earlier, faster, better planned and coordinated response, it will reduce the costs to countries and their people for response and recovery.
:: It will promote greater global and national investments in preparing for future outbreaks and strengthening national health systems.
:: It will combine public and private resources to advance global health security, and create a new insurance market for managing pandemic risk.

The World Bank Group estimates that if the PEF had existed in mid-2014 as the Ebola outbreak was spreading rapidly in West Africa, it could have mobilized an initial $100 million as early as July to severely limit the spread and severity of the epidemic. Instead, money at that scale did not begin to flow until three months later. During that three month period, the number of Ebola cases increased tenfold. The Ebola epidemic has claimed more than 11,300 lives and cost at least $10 billion to date. International assistance has totaled more than $7 billion for Ebola response and recovery.

World Cities Report 2016, Urbanization and Development: Emerging Futures

World Cities Report 2016, Urbanization and Development: Emerging Futures
UN-Habitat :: United Nations Human Settlements Programme, 2016 :: 262 pages
Full report pdf: http://wcr.unhabitat.org/?wcr_process_download=1&download_id=117118

Press Release
UN-Habitat launches the World Cities Report 2016, Urbanization and Development: Emerging Futures
New York 18 May 2016— The new global flagship report on sustainable urban development launched by UN-Habitat on Wednesday, states that a New Urban Agenda is needed to unlock the transformative power of cities. The World Cities Report 2016, Urbanization and Development: Emerging Futures, says that the top 600 cities, with 1/5th of the world’s population, produce 60 per cent of global GDP. However, when unplanned and unmanaged, urbanization can lead to increased inequality, the growth of slums and disastrous impacts on climate change, according to the report.

UN-Habitat Executive Director, Dr Joan Clos, said: “In the twenty years since the Habitat II conference, the world has seen a gathering of its population in urban areas. This has been accompanied by socioeconomic growth in many instances. But the urban landscape is changing and with it, the pressing need for a cohesive and realistic approach to urbanization. “A New Urban Agenda is required to effectively address the challenges and take advantage of the opportunities offered by urbanization,” said Clos.

Such urban expansion is wasteful in terms of land and energy consumption and increases greenhouse gas emissions. The urban centre of gravity— at least for megacities has shifted to the developing regions. In 1995, there were 22 large cities, and 14 megacities globally; by 2015, both categories of cities had doubled, with 22, or 79 per cent of the megacities located in Latin America, Asia and Africa. The fastest growing urban centres are the medium and small cities with less than one million inhabitants, which account for 59 per cent of the world’s urban population.

…Despite growing negative public perception of migrants and refugees, previous experience of refuge crisis shows that migrants can, eventually become valuable contributors to the economic and social development of countries. A major emerging urban issue capable of undermining the long-term sustainability of cities worldwide concerns insecurity and increasing risk. The fear of crime and violence continues to be pervasive in cities. New and pervasive risks affecting cities include terrorism, urban warfare, heightened securitization, and disease and pandemics…

Key Messages
:: When well-managed, urbanization fosters social and economic advancement and improved quality of life for all.
:: The current model of urbanization is unsustainable in many respects. Many cities all over the world are grossly unprepared for the challenges associated with urbanization.
:: A new agenda is required to effectively address these challenges and take advantage of the opportunities offered by urbanization.
:: The new urban agenda should promote cities and human settlements that are environmentally sustainable, resilient, socially inclusive, safe and violence-free, economically productive.

Rockefeller Foundation & Arup Debut a Pioneering Tool that Allows Cities to Better Understand Their Capacity to Address Social, Physical, or Economic Challenges

Rockefeller Foundation & Arup Debut a Pioneering Tool that Allows Cities to Better Understand Their Capacity to Address Social, Physical, or Economic Challenges
May 18, 2016
City Resilience Index (CRI) Offers Leaders a Comprehensive Analysis of Capabilities and Vulnerabilities
LONDON—Today, The Rockefeller Foundation and Arup introduced the City Resilience Index (CRI), the first-ever comprehensive tool to help cities assess their resilience, identify their vulnerabilities, and better prepare themselves for the future.

The CRI is a powerful, tested tool created to help policy-makers, urban planners and stakeholders understand and tackle the systemic challenges that increasingly threaten cities. Comprising 52 resilience indicators, the CRI assesses key resilience qualities ¬such as diversity, awareness, and self-regulation, that are critically important to building resilience within a city. The CRI gives cities the ability to assess their preparedness and ability to accommodate current and emerging challenges, through a secure online interface through which cities can enter their data. Each city’s findings can guide urban policymaking, planning, and investment.

“Cities increasingly understand that building resilience is a 21st century imperative, and now for the first time they have a way to comprehensively assess where they are strong, and where they need to improve to be ready for whatever may come their way,” said Judith Rodin, President of The Rockefeller Foundation, which supported Arup to develop the CRI. “The CRI was created over three years and in consultation with a range of cities globally. It is designed with rigor, and in a way that cities everywhere will benefit from using it as a planning and decision-making tool, that can help them realize a resilience dividend from investments in their growth and the well-being of their citizens,” added Rodin.

Designed primarily as a self-assessment, this tool will generate a resilience profile that will reveal a city’s specific strengths and weaknesses, creating a baseline to plan from and measure future progress against.

“Every city is unique, and each faces specific challenges. But, the factors that enable cities to deal with disruption are universal,” said Jo da Silva, Director, Arup. “The CRI captures the breadth of issues that contribute to a city’s resilience. It provides a practical means to measure resilience, and a common language that will enable cities to learn from each other.”

“The City Resilience Index represents an important advancement in assessing resilience, providing a new opportunity for cities, through an analysis of real data, to better assess what their resilience capabilities are,” said Michael Berkowitz, President of 100 Resilient Cities, Pioneered by The Rockefeller Foundation.

For more information on the City Resilience Index, please visit: www.cityresilienceindex.org

:: Journal Watch

:: Journal Watch
The Sentinel will track key peer-reviewed journals which address a broad range of interests in human rights, humanitarian response, health and development. It is not intended to be exhaustive. We will add to those monitored below as we encounter relevant content and upon recommendation from readers. We selectively provide full text of abstracts and other content but note that successful access to some of the articles and other content may require subscription or other access arrangement unique to the publisher. Please suggest additional journals you feel warrant coverage.

Emergence of Congenital Zika Syndrome: Viewpoint From the Front Lines

Annals of Internal Medicine
17 May 2016, Vol. 164. No. 10
http://annals.org/issue.aspx
Ideas and Opinions
Emergence of Congenital Zika Syndrome: Viewpoint From the Front Lines FREE
Federico Costa, PhD; Manoel Sarno, MD, PhD; Ricardo Khouri, PhD; Bruno de Paula Freitas, MD; Isadora Siqueira, MD, PhD; Guilherme S. Ribeiro, MD, PhD; Hugo C. Ribeiro, MD; Gubio S. Campos, PhD; Luiz C. Alcântara, PhD; Mitermayer G. Reis, MD, PhD; Scott C. Weaver, PhD; Nikos Vasilakis, PhD; Albert I. Ko, MD; and Antonio Raimundo Almeida, MD, PhD
[No abstract; Final text]
…Although recent advances in flavivirus vaccines may guide relatively rapid development of a Zika vaccine, availability is still probably years away. Treatment with a monoclonal antibody could also be developed quickly on the basis of promising past results with flaviviruses. However, systematic investigations of pregnant women and newborns will still be needed to determine the risk for transplacental infection and development of severe congenital sequelae that can, in turn, guide effective diagnostic and prevention efforts.

BMC Infectious Diseases (Accessed 21 May 2016)

BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 21 May 2016)

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Research article
Improving the uptake of pre-travel health advice amongst migrant Australians: exploring the attitudes of primary care providers and migrant community groups
Migrant travellers who return to their country of origin to visit family and friends (VFR) are less likely to seek travel-related medical care and are less likely to adhere to recommended medications …
Holly Seale, Rajneesh Kaur, Abela Mahimbo, C. Raina MacIntyre, Nicholas Zwar, Mitchell Smith, Heather Worth and Anita E Heywood
BMC Infectious Diseases 2016 16:213
Published on: 18 May 2016

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Research article
Initiation and completion rates for latent tuberculosis infection treatment: a systematic review
Control of latent tuberculosis infection (LTBI) is an important step towards tuberculosis elimination. Preventive treatment will prevent the development of disease in most cases diagnosed with LTBI.
Andreas Sandgren, Marije Vonk Noordegraaf-Schouten, Femke van Kessel, Anke Stuurman, Anouk Oordt-Speets and Marieke J. van der Werf
BMC Infectious Diseases 2016 16:204
Published on: 17 May 2016

Human newborn bacille Calmette–Guérin vaccination and risk of tuberculosis disease: a case-control study

BMC Medicine
http://www.biomedcentral.com/bmcmed/content
(Accessed 21 May 2016)

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Research article
Human newborn bacille Calmette–Guérin vaccination and risk of tuberculosis disease: a case-control study
Helen A. Fletcher, Ali Filali-Mouhim, Elisa Nemes, Anthony Hawkridge, Alana Keyser, Samuel Njikan, Mark Hatherill, Thomas J. Scriba, Brian Abel, Benjamin M. Kagina, Ashley Veldsman, Nancy Marín Agudelo, Gilla Kaplan, Gregory D. Hussey, Rafick-Pierre Sekaly and Willem A. Hanekom
Published on: 16 May 201
Abstract
Background
An incomplete understanding of the immunological mechanisms underlying protection against tuberculosis (TB) hampers the development of new vaccines against TB. We aimed to define host correlates of prospective risk of TB disease following bacille Calmette–Guérin (BCG) vaccination.
Methods
In this study, 5,726 infants vaccinated with BCG at birth were enrolled. Host responses in blood collected at 10 weeks of age were compared between infants who developed pulmonary TB disease during 2 years of follow-up (cases) and those who remained healthy (controls).
Results
Comprehensive gene expression and cellular and soluble marker analysis failed to identify a correlate of risk. We showed that distinct host responses after BCG vaccination may be the reason: two major clusters of gene expression, with different myeloid and lymphoid activation and inflammatory patterns, were evident when all infants were examined together. Cases from each cluster demonstrated distinct patterns of gene expression, which were confirmed by cellular assays.
Conclusions
Distinct patterns of host responses to Mycobacterium bovis BCG suggest that novel TB vaccines may also elicit distinct patterns of host responses. This diversity should be considered in future TB vaccine development.

BMC Public Health (Accessed 21 May 2016

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 21 May 2016)

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Research article
How equitable are community health worker programmes and which programme features influence equity of community health worker services? A systematic review
Community health workers (CHWs) are uniquely placed to link communities with the health system, playing a role in improving the reach of health systems and bringing health services closer to hard-to-reach and …
Rosalind McCollum, Woedem Gomez, Sally Theobald and Miriam Taegtmeyer
BMC Public Health 2016 16:419
Published on: 20 May 2016

Research article
Using short-message-service notification as a method to improve acute flaccid paralysis surveillance in Papua New Guinea
High quality acute flaccid paralysis (AFP) surveillance is required to maintain polio-free status of a country. Papua New Guinea (PNG) is considered as one of the highest risk countries for polio re-importation…
Siddhartha Sankar Datta, Berry Ropa, Gerard Pai Sui, Ramzi Khattar, Ravi Shankar Santhana Gopala Krishnan and Hiromasa Okayasu
BMC Public Health 2016 16:409
Published on: 17 May 2016

Debate
Critiquing the response to the Ebola epidemic through a Primary Health Care Approach
The 2014/2015 West Africa Ebola epidemic has caused the global public health community to engage in difficult self-reflection.
Vera Scott, Sarah Crawford-Browne and David Sanders
BMC Public Health 2016 16:410
Published on: 17 May 2016

Research article
Associations in the continuum of care for maternal, newborn and child health: a population-based study of 12 sub-Saharan Africa countries
Despite the progress in the Millennium Development Goals (MDGs) 4 and 5, inequity in the utilization of maternal, newborn and child health (MNCH) care services still remain high in sub-Saharan Africa (SSA).
Patrick Opiyo Owili, Miriam Adoyo Muga, Yiing-Jenq Chou, Yi-Hsin Elsa Hsu, Nicole Huang and Li-Yin Chien
BMC Public Health 2016 16:414
Published on: 17 May 2016

Deaths, late deaths, and role of infecting dose in Ebola virus disease in Sierra Leone: retrospective cohort study

British Medical Journal
21 May 2016 (vol 352, issue 8058)
http://www.bmj.com/content/353/8058

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Research Update
Deaths, late deaths, and role of infecting dose in Ebola virus disease in Sierra Leone: retrospective cohort study
BMJ 2016; 353 :i2403 (Published 17 May 2016)
Abstract
Objectives To assess the frequency of fatal recrudescence from Ebola virus disease after discharge from treatment centres, and explore the influence of infecting dose on case fatality rates.
Design Retrospective cohort study.
Setting Western Area, Sierra Leone.
Participants 151 survivors treated for Ebola virus disease at the Kerry Town treatment centre and discharged. Survivors were followed up for a vital status check at four to nine months after discharge, and again at six to 13 months after discharge. Verbal autopsies were conducted for four survivors who had died since discharge (that is, late deaths). Survivors still living in Western Area were interviewed together with their household members. Exposure level to Ebola virus disease was ascertained as a proxy of infecting dose, including for those who died.
Main outcome measures Risks and causes of late death; case fatality rates; odds ratios of death from Ebola virus disease by age, sex, exposure level, date, occupation, and household risk factors.
Results Follow-up information was obtained on all 151 survivors of Ebola virus disease, a mean of 10 months after discharge. Four deaths occurred after discharge, all within six weeks: two probably due to late complications, one to prior tuberculosis, and only one after apparent full recovery, giving a maximum estimate of recrudescence leading to death of 0.7%. In these households, 395 people were reported to have had Ebola virus disease, of whom 227 died. A further 53 people fulfilled the case definition for probable disease, of whom 11 died. Therefore, the case fatality rate was 57.5% (227/395) for reported Ebola virus disease, or 53.1% (238/448) including probable disease. Case fatality rates were higher in children aged under 2 years and adults older than 30 years, in larger households, and in infections occurring earlier in the epidemic in Sierra Leone. There was no consistent trend of case fatality rate with exposure level, although increasing exposure increased the risk of Ebola virus disease.
Conclusions In this study of survivors in Western Area, Sierra Leone, late recrudescence of severe Ebola virus disease appears to be rare. There was no evidence for an effect of infecting dose (as measured by exposure level) on the severity of disease.

Abducted children and youth in Lord’s Resistance Army in Northeastern Democratic Republic of the Congo (DRC): mechanisms of indoctrination and control

Conflict and Health
http://www.conflictandhealth.com/
[Accessed 21 May 2016]

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Research
Abducted children and youth in Lord’s Resistance Army in Northeastern Democratic Republic of the Congo (DRC): mechanisms of indoctrination and control
Jocelyn TD Kelly, Lindsay Branham and Michele R. Decker
Published on: 18 May 2016
Abstract
Background
Globally, an estimated 300,000 children under the age of 18 participate in combat situations; those in armed groups in particular suffer prolonged exposure to psychological and physical abuse. The Lord’s Resistance Army (LRA) is a rebel movement known for its widespread conscription of children; yet little is known about this process once the group moved beyond northern Uganda. In this paper, we describe the processes related to abduction and indoctrination of youth by the LRA in northeastern Democratic Republic of the Congo ( DRC).
Methods
In-depth interviews were conducted with formerly abducted children, their family members, community leaders, and service providers (total n  = 34) in four communities in LRA-affected areas of northeastern DRC. Inductive coding of transcripts was undertaken to identify salient themes.
Results
Informants articulated a range of practices by the LRA to exert high levels of control over new recruits, including strict social isolation from recent abductees; control of communication; promoting new identity formation; and compelling children to act out strictly defined gendered roles. Witchcraft and secrecy are used to intimidate recruits and to magnify perception of the group’s power. These methods promote de-identification with one’s civilian and family life; and eventually the assimilation of a new language and identity.
Conclusion
Indoctrination of newly abducted children into the LRA occurs via a complex system of control. This study provides one of the first detailed explorations of social and psychological mechanisms through which this is achieved, and focuses particularly on the gendered differences in the indoctrination process. Results support past findings that the LRA is a strategic and well-organized organization in its approach to enlisting child soldiers. Understanding some of the ways in which the LRA controls its recruits and the psychological impact of indoctrination enables reintegration programs to more effectively address these issues and serve the complex needs of formerly abducted children.

Development in Practice – Volume 26, Issue 4, 2016

Development in Practice
Volume 26, Issue 4, 2016
http://www.tandfonline.com/toc/cdip20/current

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Articles
NGO workers’ internalisation of the human rights-based approach in Bangladesh
DOI:10.1080/09614524.2016.1162286
Jae-Eun Noh*
pages 456-466
ABSTRACT
The Western origin of human rights raises the question of how the human rights-based approach to development (HRBA) is understood in non-Western countries. This article explores individual practitioners’ perceptions of the HRBA in an NGO working in Bangladesh, drawing on interviews with its workers. The data suggest that participants accept the universal values of human rights and make sense of the HRBA influenced by their organisational and national contexts. Conceptualising this process as “internalisation”, this article argues that the organisational support and workers’ field experience are critical for incorporating contextual consideration into their interpretation and practice of the HRBA.

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Articles
NGO–researcher partnerships in global health research: benefits, challenges, and approaches that promote success
DOI:10.1080/09614524.2016.1164122
Catherine Olivier, Matthew R. Hunt & Valéry Ridde
pages 444-455
Open access
Published online: 13 Apr 2016
ABSTRACT
Partnerships involving NGOs and academic researchers (NGO–R partnerships) are increasing in global health research. Such collaborations present opportunities for knowledge translation in global health, yet are also associated with challenges for establishing and sustaining effective and respectful partnerships. We conducted a narrative review of the literature to identify benefits and challenges associated with NGO–R partnerships, as well as approaches that promote successful partnerships. We illustrate this analysis with examples from our own experiences. The results suggest that collaborations characterised by trust, transparency, respect, solidarity, and mutuality contribute to the development of successful and sustainable NGO–R partnerships.

Outbreak of a new measles B3 variant in the Roma/Sinti population with transmission in the nosocomial setting, Italy, November 2015 to April 2016

Eurosurveillance
Volume 21, Issue 20, 19 May 2016
http://www.eurosurveillance.org/Public/Articles/Archives.aspx?PublicationId=11678

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Rapid communications
Outbreak of a new measles B3 variant in the Roma/Sinti population with transmission in the nosocomial setting, Italy, November 2015 to April 2016
by A Filia, A Amendola, M Faccini, M Del Manso, S Senatore, S Bianchi, BM Borrini, A Ciampelli, E Tanzi, MT Filipponi, G Piccirilli, T Lazzarotto, MG Pascucci, M Baggieri, F Magurano

Exploring Dimensions of Women’s Social Exclusion and Inclusion in Nepal

Forum for Development Studies
Volume 43, Issue 2, 2016
http://www.tandfonline.com/toc/sfds20/current

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Articles
Exploring Dimensions of Women’s Social Exclusion and Inclusion in Nepal
Haug Marit & Aadne Aasland
pages 281-309
a Norwegian Institute for Urban and Regional Research (NIBR), Oslo, Norway
DOI:10.1080/08039410.2015.1114517
Published online: 15 Dec 2015
Abstract
The article examines a variety of social exclusion and inclusion indicators grouped by domains that are commonly referred to in the social exclusion literature: economic, social, political and intra-household. Levels of social exclusion and inclusion among different groups of women across these domains are studied. This analysis reveals a complex pattern with great variations among women with different socio-demographic and socio-cultural backgrounds. Subsequently we perform a factor (principal components) analysis that identifies four major dimensions of women’s social exclusion and inclusion: outward orientation, civil society involvement, household decision-making power and monetary income. These four dimensions help us uncover factors that have contributed to the social inclusion of women, from a position of exclusion a generation ago. Crucial drivers of change have been education and urbanisation, but participation in community-based organisations has also contributed. We find that gender relations in the household are the most resistant to change and cannot be easily influenced by external change agents. There appear to be different mechanisms operating for social inclusion within each of the identified dimensions. This means there is no blueprint for any policy measures that would increase social inclusion along all the four dimensions, but measures should be specifically designed for each dimension. The data are drawn from a household survey of 2547 women between 18 and 49 years of age living in 16 districts across Nepal.

Globalization and Health [Accessed 21 May 2016]

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 21 May 2016]

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Research
Global health partnerships: building multi-national collaborations to achieve lasting improvements in maternal and neonatal health
In response to health care challenges worldwide, extensive funding has been channeled to the world’s most vulnerable health systems. Funding alone is not sufficient to address the complex issues and challenges…
Rohit Ramaswamy, Brianne Kallam, Dragica Kopic, Borislava Pujic and Medge D. Owen
Globalization and Health 2016 12:22
Published on: 20 May 2016

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Research
Discourse, ideas and power in global health policy networks: political attention for maternal and child health in the millennium development goal era
Maternal and child health issues have gained global political attention and resources in the past 10 years, due in part to their prominence on the Millennium Development Goal agenda and the use of evidence-based…
Lori McDougall
Globalization and Health 2016 12:21
Published on: 18 May 2016

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Research
From local to global: a qualitative review of the multi-leveled impact of a multi-country health research capacity development partnership on maternal health in Sudan
There is a substantial body of literature on the principles of good partnerships and the rationale for such partnerships in research capacity strengthening. This paper illustrates the long term effects…
Khalifa Elmusharaf, Hanan Tahir, Diarmuid O’ Donovan, Ruairi Brugha, Mamoun Homeida, Amal M. O. Abbas and Elaine Byrne
Globalization and Health 2016 12:20
Published on: 16 May 2016

Globalization and Health [Accessed 21 May 2016]

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 21 May 2016]

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Research
Global health partnerships: building multi-national collaborations to achieve lasting improvements in maternal and neonatal health
In response to health care challenges worldwide, extensive funding has been channeled to the world’s most vulnerable health systems. Funding alone is not sufficient to address the complex issues and challenges…
Rohit Ramaswamy, Brianne Kallam, Dragica Kopic, Borislava Pujic and Medge D. Owen
Globalization and Health 2016 12:22
Published on: 20 May 2016

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Research
Discourse, ideas and power in global health policy networks: political attention for maternal and child health in the millennium development goal era
Maternal and child health issues have gained global political attention and resources in the past 10 years, due in part to their prominence on the Millennium Development Goal agenda and the use of evidence-based…
Lori McDougall
Globalization and Health 2016 12:21
Published on: 18 May 2016

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Research
From local to global: a qualitative review of the multi-leveled impact of a multi-country health research capacity development partnership on maternal health in Sudan
There is a substantial body of literature on the principles of good partnerships and the rationale for such partnerships in research capacity strengthening. This paper illustrates the long term effects…
Khalifa Elmusharaf, Hanan Tahir, Diarmuid O’ Donovan, Ruairi Brugha, Mamoun Homeida, Amal M. O. Abbas and Elaine Byrne
Globalization and Health 2016 12:20
Published on: 16 May 2016

Which health research gets used and why? An empirical analysis of 30 cases

Health Research Policy and Systems
http://www.health-policy-systems.com/content
[Accessed 21 May 2016]

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Research
Which health research gets used and why? An empirical analysis of 30 cases
Maarten Olivier Kok, John Owusu Gyapong, Ivan Wolffers, David Ofori-Adjei and Joost Ruitenberg
Published on: 17 May 2016
Abstract
Background
While health research is considered essential for improving health worldwide, it remains unclear how it is best organized to contribute to health. This study examined research that was part of a Ghanaian-Dutch research program that aimed to increase the likelihood that results would be used by funding research that focused on national research priorities and was led by local researchers. The aim of this study was to map the contribution of this research to action and examine which features of research and translation processes were associated with the use of the results.
Methods
Using Contribution Mapping, we systematically examined how 30 studies evolved and how results were used to contribute to action. We combined interviews with 113 purposively selected key informants, document analysis and triangulation to map how research and translation processes evolved and contributions to action were realized. After each case was analysed separately, a cross-case analysis was conducted to identify patterns in the association between features of research processes and the use of research.
Results
The results of 20 of the 30 studies were used to contribute to action within 12 months. The priority setting and proposal selection process led to the funding of studies which were from the outset closely aligned with health sector priorities. Research was most likely to be used when it was initiated and conducted by people who were in a position to use their results in their own work. The results of 17 out of 18 of these user-initiated studies were translated into action. Other features of research that appeared to contribute to its use were involving potential key users in formulating proposals and developing recommendations.
Conclusions
Our study underlines the importance of supporting research that meets locally-expressed needs and that is led by people embedded in the contexts in which results can be used. Supporting the involvement of health sector professionals in the design, conduct and interpretation of research appears to be an especially worthwhile investment.

International Journal of Epidemiology – Volume 45 Issue 2 April 2016

International Journal of Epidemiology
Volume 45 Issue 2 April 2016
http://ije.oxfordjournals.org/content/current

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Editorials
African partnerships through the H3Africa Consortium bring a genomic dimension to longitudinal population studies on the continent
Michèle Ramsay1,*, Osman Sankoh2,3,
as members of the AWI-Gen study and the H3Africa Consortium
Author Affiliations
1Sydney Brenner Institute for Molecular Bioscience and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa,
2INDEPTH Network, Kanda, Accra, Ghana and
3Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
*Corresponding author. E-mail: michele.ramsay@wits.ac.za
[Extract]
A health and epidemiological transition is enveloping the African continent from the southern and northern regions where the prevalence of obesity has rapidly increased over the past three decades.1 In the wake of the transition to increased urbanization follow increased rates of hypertension, stroke and type 2 diabetes (T2D). Despite the widespread HIV, TB and malaria epidemics, age-standardized mortality for non-communicable diseases (the probability of dying from one of the four main NCDs—CVD, cancer, chronic respiratory disease and diabetes) between the ages of 30 and 70 years (comparable estimates for 2012) is over 25% in South Africa compared with less than 15% in North America and Europe.2

Good health-related epidemiological data from most African populations are sparse. When accessing global data on non-communicable diseases, it becomes clear that many African countries have no data; in some there is sporadic reporting on specific variables and then there are pockets of excellent data, albeit usually on smaller cohorts, or only in specific regions. For this reason, African health data are often modelled and predictions are based on models that are supported with little and sub-optimal information. This highlights an urgent need to support more systematic approaches to collecting epidemiological data in Africa…

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Health Policies and Interventions
Loss of confidence in vaccines following media reports of infant deaths after hepatitis B vaccination in China
Int. J. Epidemiol. (2016) 45 (2): 441-449 doi:10.1093/ije/dyv349
Wenzhou Yu, Dawei Liu, Jingshan Zheng, Yanmin Liu, Zhijie An, Lance Rodewald, Guomin Zhang, Qiru Su, Keli Li, Disha Xu, Fuzhen Wang, Ping Yuan, Wei Xia, Guijun Ning, Hui Zheng,
Yaozhu Chu, Jian Cui, Mengjuan Duan, Lixin Hao, Yuqing Zhou, Zhenhua Wu, Xuan Zhang,
Fuqiang Cui, Li Li, and Huaqing Wang
Abstract
Background: China reduced hepatitis B virus (HBV) infection by 90% among children under 5 years old with safe and effective hepatitis B vaccines (HepB). In December 2013, this success was threatened by widespread media reports of infant deaths following HepB administration. Seventeen deaths and one case of anaphylactic shock following HBV vaccination had been reported.
Methods: We conducted a telephone survey to measure parental confidence in HepB in eleven provinces at four points in time; reviewed maternal HBV status and use of HepB for newborns in birth hospitals in eight provinces before and after the event; and monitored coverage with hepatitis B vaccine and other programme vaccines in ten provinces.
Results: HepB from the implicated company was suspended during the investigation, which showed that the deaths were not caused by HepB vaccination. Before the event, 85% respondents regarded domestic vaccines as safe, decreasing to 26.7% during the event. During the height of the crisis, 30% of parents reported being hesitant to vaccinate and 18.4% reported they would refuse HepB. Use of HepB in the monitored provinces decreased by 18.6%, from 53 653 doses the week before the event to 43 688 doses during the week that Biokangtai HepB was suspended. Use of HepB within the first day of life decreased by 10% among infants born to HBsAg-negative mothers, and by 6% among infants born to HBsAg-positive mothers. Vaccine refusal and HepB birth dose rates returned to baseline within 2 months; confidence increased, but remained below baseline.
Conclusions: The HBV vaccine event resulted in the suspension of a safe vaccine, which was associated with a decline of parental confidence, and refusal of vaccination. Suspension of a vaccine can lead to loss of confidence that is difficult to recover. Timely and credible investigation, accompanied by proactive outreach to stakeholders and the media, may help mitigate negative impact of future coincidental adverse events following immunization.

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Effectiveness of a pay-for-performance intervention to improve maternal and child health services in Afghanistan: a cluster-randomized trial
Cyrus Y Engineer, Elina Dale, Anubhav Agarwal, Arunika Agarwal, Olakunle Alonge, Anbrasi Edward, Shivam Gupta, Holly B Schuh, Gilbert Burnham, and David H Peters
Int. J. Epidemiol. (2016) 45 (2): 451-459 doi:10.1093/ije/dyv362
Abstract
Background: A cluster randomized trial of a pay-for-performance (P4P) scheme was implemented in Afghanistan to test whether P4P could improve maternal and child (MCH) services.
Methods: All 442 primary care facilities in 11 provinces were matched by type of facility and outpatient volume, and randomly assigned to the P4P or comparison arm. P4P facilities were given bonus payments based on the MCH services provided. An endline household sample survey was conducted in 72 randomly selected matched pair catchment areas (3421 P4P households; 3427 comparison).The quality of services was assessed in 81 randomly sampled matched pairs of facilities. Data collectors and households were blinded to the intervention assignment. MCH outcomes were assessed at the cluster level.
Results: There were no substantial differences in any of the five MCH coverage indicators (P4P vs comparison): modern contraception(10.7% vs 11.2% (P = 0.90); antenatal care: 56.2% vs 55.6% (P = 0.94); skilled birth attendance (33.9% vs 28.5%, P = 0.17); postnatal care (31.2% vs 30.3%, P = 0.98); and childhood pentavalent3 vaccination (49.6 vs 52.3%, P = 0.41), or in the equity measures. There were substantial increases in the quality of history and physical examinations index (P = 0.01); client counselling index (P = 0.01); and time spent with patients (P = 0.05). Health workers reported limited understanding about the bonuses.
Conclusions: The intervention had minimal effect, possibly due to difficulties communicating with health workers and inattention to demand-side factors. P4P interventions need to consider management and community demand issues.

Journal of Community Health – Volume 41, Issue 3, June 2016

Journal of Community Health
Volume 41, Issue 3, June 2016
http://link.springer.com/journal/10900/41/3/page/1

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Original Paper
Development of a Cost-Effective Educational Tool to Promote Acceptance of the HPV Vaccination by Hispanic Mothers
Doerthe Brueggmann, Neisha Opper, Juan Felix, David A. Groneberg, Daniel R. MishellJr., Jenny M. Jaque
Abstract
Although vaccination against the Human Papilloma Virus (HPV) reduces the risk of related morbidities, the vaccine uptake remains low in adolescents. This has been attributed to limited parental knowledge and misconceptions. In this cross sectional study, we assessed the (1) clarity of educational material informing Hispanic mothers about HPV, cervical cancer and the HPV vaccine, (2) determined vaccination acceptability and (3) identified predictors of vaccine acceptance in an underserved health setting. 418 Hispanic mothers received the educational material and completed an anonymous survey. 91 % of participants understood most or all of the information provided. 77 % of participants reported vaccine acceptance for their children; this increased to 84 % when only those with children eligible to receive vaccination were included. Significant positive predictors of maternal acceptance of the HPV vaccine for their children were understanding most or all of the provided information, older age and acceptance of the HPV vaccine for themselves. Concerns about safety and general dislike of vaccines were negatively associated with HPV vaccine acceptance. Prior knowledge, level of education, previous relevant gynecologic history, general willingness to vaccinate and other general beliefs about vaccines were not significantly associated with HPV vaccine acceptance. The majority of participants reported understanding of the provided educational material. Vaccine acceptability was fairly high, but was even higher among those who understood the information. This study documents a cost-effective way to provide Hispanic mothers with easy-to-understand HPV-related information that could increase parental vaccine acceptability and future vaccine uptake among their children.

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Original Paper
Help-Seeking Behavior and Health Care Navigation by Bhutanese Refugees
Katherine Yun , Papia Paul, Parangkush Subedi, Leela Kuikel, Giang T. Nguyen, Frances K. Barg
Abstract
The objective of this study was to document barriers to care, help-seeking behaviors, and the impact of a community-based patient navigation intervention on patient activation levels among Bhutanese refugees in the U.S. Data sources comprised 35 intake and 34 post-intervention interviews with program participants, 14 intake and 14 post-intervention interviews with patient navigators, and 164 case notes. Textual data were analyzed using the constant comparison method. Patient activation level was assessed at both time points. Participants had limited English proficiency (97 %), limited literacy (69 %), and the lowest level of patient activation (69 %). Participants routinely experienced complex insurance access, coverage, and payment problems and had limited healthcare-related life skills. Help-seeking began within social networks, with high reliance on bilingual, literate family members perceived to have experience with “the system.” Help-seeking was not stigmatized and was instead consistent with societal norms valuing mutual assistance. Participants preferred helpers to act as proxies and required repeated social modeling by peers to gain confidence applying healthcare-related life skills. Following the intervention, only one-third reported the lowest level of patient activation (35 %) and one-third were highly activated (32 %). Bhutanese refugees overcome healthcare access barriers by seeking help from a network of support that begins within the community. Community health workers serving as patient navigators are readily sought out, and this approach is concordant with cultural expectations for mutual assistance. Community health workers serving immigrant groups should model healthcare-related life skills in addition to providing direct assistance.