Globalization and Health [Accessed 18 June 2016]

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 18 June 2016]
Commentary

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Measuring success in global health diplomacy: lessons from marketing food to children in India
Global health diplomacy (GHD) focuses on international negotiation; principally between nation states, but increasingly non-state actors However, agreements made at the global level have to be enacted at the n…
Richard Smith and Rachel Irwin
Globalization and Health 2016 12:28
Published on: 16 June 2016

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Methodology
Assessing the health impact of transnational corporations: its importance and a framework
The adverse health and equity impacts of transnational corporations’ (TNCs) practices have become central public health concerns as TNCs increasingly dominate global trade and investment and shape national eco…
Frances E. Baum, David M. Sanders, Matt Fisher, Julia Anaf, Nicholas Freudenberg, Sharon Friel, Ronald Labonté, Leslie London, Carlos Monteiro, Alex Scott-Samuel and Amit Sen
Globalization and Health 2016 12:27
Published on: 15 June 2016

Can a quality improvement project impact maternal and child health outcomes at scale in northern Ghana?

Health Research Policy and Systems
http://www.health-policy-systems.com/content
[Accessed 18 June 2016]

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Research
Can a quality improvement project impact maternal and child health outcomes at scale in northern Ghana?
Quality improvement (QI) interventions are becoming more common in low- and middle-income countries, yet few studies have presented impact evaluations of these approaches. In this paper, we present an impact e…
Kavita Singh, Paul Brodish, Ilene Speizer, Pierre Barker, Issac Amenga-Etego, Ireneous Dasoberi, Ernest Kanyoke, Eric A. Boadu, Elma Yabang and Sodzi Sodzi-Tettey
Health Research Policy and Systems 2016 14:45
Published on: 16 June 2016

Is the United States Prepared for a Major Zika Virus Outbreak?

JAMA
June 14, 2016, Vol 315, No. 22
http://jama.jamanetwork.com/issue.aspx

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Viewpoint
Is the United States Prepared for a Major Zika Virus Outbreak? FREE
Lawrence O. Gostin, JD; James G. Hodge Jr, JD, LLM
[Initial text]
From its initial discovery in Ugandan forests nearly 70 years ago, Zika virus has emerged as a worldwide public health crisis, with active transmission in more than 40 countries in the Americas and Caribbean. On February 1, 2016, the World Health Organization (WHO) declared a Public Health Emergency of International Concern (PHEIC), concerned about clusters of microcephaly and Guillain-Barré syndrome (GBS). A week later, the Centers for Disease Control and Prevention (CDC) triggered the highest “level 1” activation of its emergency operations center, and President Obama requested $1.86 billion in emergency funding.1 On April 7, the WHO reported there is scientific consensus that Zika is a cause of microcephaly and GBS.

Although none of the continental states has reported local mosquito-borne transmission, Health Secretary Sylvia Burwell warned that Zika has a “significant potential to affect national security or the health of Americans.”2 The virus severely threatens Puerto Rico, with one-quarter of its 3.5 million inhabitants projected to be infected.3 The Olympics in Brazil will have an amplifying affect because the competition will be during the Northern summer. Travelers visiting or returning to the United States could likely escalate the spread of Zika. Epidemiologists estimate that Zika could affect a majority of US states including large cities where Aedes species mosquitos are active.

Is the United States prepared for major clusters of Zika? Certainly, a highly functioning health system will help protect the domestic population. Yet there are signs of unpreparedness with insufficient resources and variable legal authorities…

The Lancet – Jun 18, 2016 Volume 387 Number 10037

The Lancet
Jun 18, 2016 Volume 387 Number 10037 p2479-2574
http://www.thelancet.com/journals/lancet/issue/current

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Comment
AIDS 2016: from aspiration to implementation
Kenneth H Mayer, Olive Shisana, Chris Beyrer
Summary
Since AIDS was first recognised in 1981, more than 75 million HIV infections and more than 36 million deaths have occurred.1 HIV infection is no longer an inexorable death sentence but a chronic manageable infection. Key factors responsible for this transformation have been an understanding of the modes of HIV transmission,2 the development of effective combination antiretroviral therapy,3 and the validation of surrogate markers to monitor the response to treatment.4 But currently less than half of all people living with HIV worldwide have access to life-saving antiretroviral therapy,5 at a time when donor interest is uncertain and global funding flattening.

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Articles
National spending on health by source for 184 countries between 2013 and 2040
Joseph L Dieleman, Tara Templin, Nafis Sadat, Patrick Reidy, Abigail Chapin, Kyle Foreman, Annie Haakenstad, Tim Evans, Christopher J L Murray, Christoph Kurowski
2521
Summary
Background
A general consensus exists that as a country develops economically, health spending per capita rises and the share of that spending that is prepaid through government or private mechanisms also rises. However, the speed and magnitude of these changes vary substantially across countries, even at similar levels of development. In this study, we use past trends and relationships to estimate future health spending, disaggregated by the source of those funds, to identify the financing trajectories that are likely to occur if current policies and trajectories evolve as expected.
Methods
We extracted data from WHO’s Health Spending Observatory and the Institute for Health Metrics and Evaluation’s Financing Global Health 2015 report. We converted these data to a common purchasing power-adjusted and inflation-adjusted currency. We used a series of ensemble models and observed empirical norms to estimate future government out-of-pocket private prepaid health spending and development assistance for health. We aggregated each country’s estimates to generate total health spending from 2013 to 2040 for 184 countries. We compared these estimates with each other and internationally recognised benchmarks.
Findings
Global spending on health is expected to increase from US$7·83 trillion in 2013 to $18·28 (uncertainty interval 14·42–22·24) trillion in 2040 (in 2010 purchasing power parity-adjusted dollars). We expect per-capita health spending to increase annually by 2·7% (1·9–3·4) in high-income countries, 3·4% (2·4–4·2) in upper-middle-income countries, 3·0% (2·3–3·6) in lower-middle-income countries, and 2·4% (1·6–3·1) in low-income countries. Given the gaps in current health spending, these rates provide no evidence of increasing parity in health spending. In 1995 and 2015, low-income countries spent $0·03 for every dollar spent in high-income countries, even after adjusting for purchasing power, and the same is projected for 2040. Most importantly, health spending in many low-income countries is expected to remain low. Estimates suggest that, by 2040, only one (3%) of 34 low-income countries and 36 (37%) of 98 middle-income countries will reach the Chatham House goal of 5% of gross domestic product consisting of government health spending.
Interpretation
Despite remarkable health gains, past health financing trends and relationships suggest that many low-income and lower-middle-income countries will not meet internationally set health spending targets and that spending gaps between low-income and high-income countries are unlikely to narrow unless substantive policy interventions occur. Although gains in health system efficiency can be used to make progress, current trends suggest that meaningful increases in health system resources will require concerted action.

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Articles
Development assistance for health: past trends, associations, and the future of international financial flows for health
Joseph L Dieleman, Matthew T Schneider, Annie Haakenstad, Lavanya Singh, Nafis Sadat, Maxwell Birger, Alex Reynolds, Tara Templin, Hannah Hamavid, Abigail Chapin, Christopher J L Murray
2536
Summary
Background
Disbursements of development assistance for health (DAH) have risen substantially during the past several decades. More recently, the international community’s attention has turned to other international challenges, introducing uncertainty about the future of disbursements for DAH.
Methods
We collected audited budget statements, annual reports, and project-level records from the main international agencies that disbursed DAH from 1990 to the end of 2015. We standardised and combined records to provide a comprehensive set of annual disbursements. We tracked each dollar of DAH back to the source and forward to the recipient. We removed transfers between agencies to avoid double-counting and adjusted for inflation. We classified assistance into nine primary health focus areas: HIV/AIDS, tuberculosis, malaria, maternal health, newborn and child health, other infectious diseases, non-communicable diseases, Ebola, and sector-wide approaches and health system strengthening. For our statistical analysis, we grouped these health focus areas into two categories: MDG-related focus areas (HIV/AIDS, tuberculosis, malaria, child and newborn health, and maternal health) and non-MDG-related focus areas (other infectious diseases, non-communicable diseases, sector-wide approaches, and other). We used linear regression to test for structural shifts in disbursement patterns at the onset of the Millennium Development Goals (MDGs; ie, from 2000) and the global financial crisis (impact estimated to occur in 2010). We built on past trends and associations with an ensemble model to estimate DAH through the end of 2040.
Findings
In 2015, US$36·4 billion of DAH was disbursed, marking the fifth consecutive year of little change in the amount of resources provided by global health development partners. Between 2000 and 2009, DAH increased at 11·3% per year, whereas between 2010 and 2015, annual growth was just 1·2%. In 2015, 29·7% of DAH was for HIV/AIDS, 17·9% was for child and newborn health, and 9·8% was for maternal health. Linear regression identifies three distinct periods of growth in DAH. Between 2000 and 2009, MDG-related DAH increased by $290·4 million (95% uncertainty interval [UI] 174·3 million to 406·5 million) per year. These increases were significantly greater than were increases in non-MDG DAH during the same period (p=0·009), and were also significantly greater than increases in the previous period (p<0·0001). Between 2000 and 2009, growth in DAH was highest for HIV/AIDS, malaria, and tuberculosis. Since 2010, DAH for maternal health and newborn and child health has continued to climb, although DAH for HIV/AIDS and most other health focus areas has remained flat or decreased. Our estimates of future DAH based on past trends and associations present a wide range of potential futures, although our mean estimate of $64·1 billion (95% UI $30·4 billion to $161·8 billion) shows an increase between now and 2040, although with a large uncertainty interval.
Interpretation
Our results provide evidence of two substantial shifts in DAH growth during the past 26 years. DAH disbursements increased faster in the first decade of the 2000s than in the 1990s, but DAH associated with the MDGs increased the most out of all focus areas. Since 2010, limited growth has characterised DAH and we expect this pattern to persist. Despite the fact that DAH is still growing, albeit minimally, DAH is shifting among the major health focus areas, with relatively little growth for HIV/AIDS, malaria, and tuberculosis. These changes in the growth and focus of DAH will have critical effects on health services in some low-income countries. Coordination and collaboration between donors and domestic governments is more important than ever because they have a great opportunity and responsibility to ensure robust health systems and service provision for those most in need.

The International Health Regulations: The Governing Framework for Global Health Security

The Milbank Quarterly
A Multidisciplinary Journal of Population Health and Health Policy
June 2016 Volume 94, Issue 2 Pages 225–435
http://onlinelibrary.wiley.com/doi/10.1111/1468-0009.2016.94.issue-2/issuetoc

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Original Investigation
The International Health Regulations: The Governing Framework for Global Health Security
LAWRENCE O. GOSTIN1,* and REBECCA KATZ2
Version of Record online: 11 MAY 2016
DOI: 10.1111/1468-0009.1218
Abstract
Context
The International Health Regulations (IHR) have been the governing framework for global health security for the past decade and are a nearly universally recognized World Health Organization (WHO) treaty, with 196 States Parties. In the wake of the Ebola epidemic, major global commissions have cast doubt on the future effectiveness of the IHR and the leadership of the WHO.
Methods
We conducted a review of the historical origins of the IHR and their performance over the past 10 years and analyzed all of the ongoing reform panel efforts to provide a series of politically feasible recommendations for fundamental reform.
Findings
We propose a series of recommendations with realistic pathways for change. These recommendations focus on the development and strengthening of IHR core capacities; independently assessed metrics; new financing mechanisms; harmonization with the Global Health Security Agenda, Performance of Veterinary Services (PVS) Pathways, the Pandemic Influenza Preparedness Framework, and One Health strategies; public health and clinical workforce development; Emergency Committee transparency and governance; tiered public health emergency of international concern (PHEIC) processes; enhanced compliance mechanisms; and an enhanced role for civil society.
Conclusions
Empowering the WHO and realizing the IHR’s potential will shore up global health security—a vital investment in human and animal health—while reducing the vast economic consequences of the next global health emergency.

Nature – Volume 534 Number 7607 pp296-430 16 June 2016

Nature
Volume 534 Number 7607 pp296-430 16 June 2016
http://www.nature.com/nature/current_issue.html

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Comment
Nutrition: Fall in fish catch threatens human health
Christopher Golden and colleagues calculate that declining numbers of marine fish will spell more malnutrition in many developing nations.

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Policy: Map the interactions between Sustainable Development Goals
Måns Nilsson, Dave Griggs and Martin Visbeck present a simple way of rating relationships between the targets to highlight priorities for integrated policy.

Oxford Monitor of Forced Migration – OxMo Vol. 6, No. 1

Oxford Monitor of Forced Migration
OxMo Vol. 6, No. 1
http://oxmofm.com/current-issue/

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Firsthand Monitor
SYLVAIN GAETAN, Refugees are not a Burden, but a Resource

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Field Monitor
CATHERINE BLANCHARD, PAULINE CARNET AND JONATHAN ELLIS, The Azure Payment Card: the Humanitarian Cost of a Cashless System
This piece describes research conducted by the British Red Cross into the effectiveness of the
Azure payment card in providing support to refused asylum seekers. It includes the viewpoint
of organisations working with these clients and the lived experience of refused asylum
seekers. The research concludes that the Azure card and support does not allow refused
asylum seekers to meet their basic needs and live with dignity. Our recommendations
included abolishing the Azure card. The piece ends with a description of the advocacy we
engaged in, based on the recommendations of the research.

MARTINA MANARA, Never Settled. The Informal Refugee Settlement of Borgo Mezzanone and its Effects on Asylum Seekers in the Reception Centre
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Policy Monitor
LAN HOANG, Hong Kong’s Unified Screening System: Lack of unification to Improve Asylum Seekers’ Reality

DIANA IHRING, Selective Border Policies and ‘Victimhood’: The Shrinking Protection Space for Migrants in Europe

KAMYAR JARAHZADEH, Those Who Follow the Rules: Exploring Life for Afghan Refugees in Turkey

Pediatrics – June 2016, VOLUME 137 / ISSUE 6

Pediatrics
June 2016, VOLUME 137 / ISSUE 6
http://pediatrics.aappublications.org/content/137/6?current-issue=y

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Review Articles
Learning Problems in Children of Refugee Background: A Systematic Review
Hamish R. Graham, Ripudaman S. Minhas, Georgia Paxton
Pediatrics Jun 2016, 137 (6) e20153994; DOI: 10.1542/peds.2015-3994
Abstract
CONTEXT: Learning problems are common, affecting up to 1 in 10 children. Refugee children may have cumulative risk for educational disadvantage, but there is limited information on learning in this population.
OBJECTIVE: To review the evidence on educational outcomes and learning problems in refugee children and to describe their major risk and resource factors.
DATA SOURCES: Medline, Embase, PubMed, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, and Education Resources Information Center.
STUDY SELECTION: English-language articles addressing the prevalence and determinants of learning problems in refugee children.
DATA EXTRACTION: Data were extracted and analyzed according to Arksey and O’Malley’s descriptive analytical method for scoping studies.
RESULTS: Thirty-four studies were included. Refugee youth had similar secondary school outcomes to their native-born peers; there were no data on preschool or primary school outcomes. There were limited prevalence data on learning problems, with single studies informing most estimates and no studies examining specific language disorders or autism spectrum disorders. Major risk factors for learning problems included parental misunderstandings about educational styles and expectations, teacher stereotyping and low expectations, bullying and racial discrimination, premigration and postmigration trauma, and forced detention. Major resource factors for success included high academic and life ambition, “gift-and-sacrifice” motivational narratives, parental involvement in education, family cohesion and supportive home environment, accurate educational assessment and grade placement, teacher understanding of linguistic and cultural heritage, culturally appropriate school transition, supportive peer relationships, and successful acculturation.
LIMITATIONS: Studies are not generalizable to other cohorts.
CONCLUSIONS: This review provides a summary of published prevalence estimates for learning problems in resettled refugee children, highlights key risk and resource factors, and identifies gaps in research.
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State-of-the-art Review Articles
Breaking the Intergenerational Cycle of Disadvantage: The Three Generation Approach
Tina L. Cheng, Sara B. Johnson, Elizabeth Goodman
Pediatrics Jun 2016, 137 (6) e20152467; DOI: 10.1542/peds.2015-2467
Abstract
Health disparities in the United States related to socioeconomic status are persistent and pervasive. This review highlights how social disadvantage, particularly low socioeconomic status and the health burden it brings, is passed from 1 generation to the next. First, we review current frameworks for understanding the intergenerational transmission of health disparities and provide 4 illustrative examples relevant to child health, development, and well-being. Second, the leading strategy to break the cycle of poverty in young families in the United States, the 2-generation approach, is reviewed. Finally, we propose a new 3-generation approach that must combine with the 2-generation approach to interrupt the intergenerational cycle of disadvantage and eliminate health disparities.

If Numbers Can Speak, Who Listens? Creating Engagement and Learning for Effective Uptake of DRR Investment in Developing Countries

PLOS Currents: Disasters
http://currents.plos.org/disasters/
[Accessed 18 June 2016]

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Discussion
If Numbers Can Speak, Who Listens? Creating Engagement and Learning for Effective Uptake of DRR Investment in Developing Countries
June 13, 2016 ·
Introduction: With a renewed emphasis on evidence-based risk sensitive investment promoted under the Sendai Framework for Disaster Risk Reduction 2015-2030, technical demands for analytical tools such as probabilistic cost-benefit analysis (CBA) will likely increase in the foreseeable future. This begs a number of pragmatic questions such as whether or not sophisticated quantitative appraisal tools are effective in raising policy awareness and what alternatives are available.
Method: This article briefly reviews current practices of analytical tools such as probabilistic cost-benefit analysis and identifies issues associated with its applications in small scale community based DRR interventions.
Results: The article illustrate that while best scientific knowledge should inform policy and practice in principle, it should not create an unrealistic expectation that the state-of-the art methods must be used in all cases, especially for small scale DRR interventions in developing countries, where data and resource limitations and uncertainty are high, and complex interaction and feedback may exist between DRR investment, community response and longer-term development outcome.
Discussion: Alternative and more participatory approaches for DRR appraisals are suggested which includes participatory serious games that are increasingly being used to raise awareness and identify pragmatic strategies for change that are needed to bring about successful uptake of DRR investment and implementation of DRR mainstreaming.

Delinking Investment in Antibiotic Research and Development from Sales Revenues: The Challenges of Transforming a Promising Idea into Reality

PLoS Medicine
http://www.plosmedicine.org/
(Accessed 18 June 2016)

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Essay
Delinking Investment in Antibiotic Research and Development from Sales Revenues: The Challenges of Transforming a Promising Idea into Reality
Kevin Outterson, Unni Gopinathan, Charles Clift, Anthony D. So, Chantal M. Morel, John-Arne Røttingen
| published 14 Jun 2016 | PLOS Medicine
Summary Points
:: The current business model for antibiotics is plagued by market failures and perverse incentives that both work against conservation efforts and provide insufficient rewards to drive the development of much-needed new treatments for resistant infection.
:: Many new incentive mechanisms have been proposed to realign incentives and support innovation and conservation over the long term. The most promising of these are based on the idea of delinking rewards from sales volume of the antibiotic—the notion of “delinkage.”
:: Some critical design issues for delinkage remain, such as how to secure access to badly needed new products when resistance renders existing treatments ineffective, an increasingly urgent global problem. The issue of global access to antibiotics is not sufficiently addressed de facto by a delinked mechanism, and, as such, it must be addressed explicitly through specific design features of new mechanisms, including defining the eligibility criteria for delinkage rewards and appropriate management of intellectual property.
:: The idea of establishing a new business model to drive antibiotic development and improve conservation currently has the world’s attention. We must now work quickly to examine the remaining design questions to address this major public health concern for the longer term.

Participatory Surveillance and the Zika Crisis: Opportunities and Caveats

PLoS Neglected Tropical Diseases
http://www.plosntds.org/

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Digital Participatory Surveillance and the Zika Crisis: Opportunities and Caveats
Claudia Pagliari, Santosh Vijaykumar
Viewpoints | published 13 Jun 2016 | PLOS Neglected Tropical Diseases
http://dx.doi.org/10.1371/journal.pntd.0004795
Introduction
Managing the global threat of Zika requires innovative solutions. This article examines the potential of Digital Participatory Surveillance to support the management of global disease outbreaks by enabling citizens to report signs of infection. We discuss the status of the current evidence-base, contextual factors influencing user engagement and data quality, challenges for evaluation, and unique aspects of Zika with implications for design. We also suggest priorities for research, development and practice, to help translate the theoretical benefits of these methods into meaningful improvements in outbreak monitoring and public health.

Antibody Secreting Cell Responses following Vaccination with Bivalent Oral Cholera Vaccine among Haitian Adults

PLoS Neglected Tropical Diseases
http://www.plosntds.org/

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Research Article
Antibody Secreting Cell Responses following Vaccination with Bivalent Oral Cholera Vaccine among Haitian Adults
Wilfredo R. Matias, Brie Falkard, Richelle C. Charles, Leslie M. Mayo-Smith, Jessica E. Teng, Peng Xu, Pavol Kovac, Edward T. Ryan, Firdausi Qadri, Molly F. Franke, Louise C. Ivers, Jason B. Harris
| published 16 Jun 2016 | PLOS Neglected Tropical Diseases
http://dx.doi.org/10.1371/journal.pntd.0004753
Abstract
Background
The bivalent whole-cell (BivWC) oral cholera vaccine (Shanchol) is effective in preventing cholera. However, evaluations of immune responses following vaccination with BivWC have been limited. To determine whether BivWC induces significant mucosal immune responses, we measured V. cholerae O1 antigen-specific antibody secreting cell (ASC) responses following vaccination.
Methodology/Principal Findings
We enrolled 24 Haitian adults in this study, and administered doses of oral BivWC vaccine 14 days apart (day 0 and day 14). We drew blood at baseline, and 7 days following each vaccine dose (day 7 and 21). Peripheral blood mononuclear cells (PBMCs) were isolated, and ASCs were enumerated using an ELISPOT assay. Significant increases in Ogawa (6.9 cells per million PBMCs) and Inaba (9.5 cells per million PBMCs) OSP-specific IgA ASCs were detected 7 days following the first dose (P < 0.001), but not the second dose. The magnitude of V. cholerae-specific ASC responses did not appear to be associated with recent exposure to cholera. ASC responses measured against the whole lipolysaccharide (LPS) antigen and the OSP moiety of LPS were equivalent, suggesting that all or nearly all of the LPS response targets the OSP moiety.
Conclusions/Significance
Immunization with the BivWC oral cholera vaccine induced ASC responses among a cohort of healthy adults in Haiti after a single dose. The second dose of vaccine resulted in minimal ASC responses over baseline, suggesting that the current dosing schedule may not be optimal for boosting mucosal immune responses to V. cholerae antigens for adults in a cholera-endemic area.
Author Summary
The bivalent whole-cell (BivWC) oral cholera vaccine (Shanchol) is effective in preventing cholera. Despite its increasing use as part of comprehensive cholera prevention and control efforts, evaluations of immune responses following vaccination with BivWC have been limited. In this study, we measured the development of cholera-specific antibody secreting cells, markers of mucosal immunity, following vaccination with BivWC among a population of adults in Haiti, where cholera is now endemic. BivWC induced development of robust immune responses following the first dose of vaccine, but similar ASC responses were not detected following the second dose, suggesting that the currently recommended 14-day interval between doses may not be optimal for boosting mucosal immune responses among adults in cholera endemic regions. These findings suggest that additional evaluation of the optimal dosing schedule for oral cholera vaccines is warranted with the goal of improving long-term immunity.

Reproductive Health [Accessed 18 June 2016]

Reproductive Health
http://www.reproductive-health-journal.com/content
[Accessed 18 June 2016]

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Research
Inequalities in the coverage of place of delivery and skilled birth attendance: analyses of cross-sectional surveys in 80 low and middle-income countries
Having a health worker with midwifery skills present at delivery is one of the key interventions to reduce maternal and newborn mortality. We sought to estimate the frequencies of (a) skilled birth attendant c…
Gary Joseph, Inácio Crochemore Mohnsam da Silva, Fernando C. Wehrmeister, Aluísio J. D. Barros and Cesar G. Victora
Reproductive Health 2016 13:77
Published on: 17 June 2016

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Study protocol
Global, regional and national levels and trends of preterm birth rates for 1990 to 2014: protocol for development of World Health Organization estimates
The official WHO estimates of preterm birth are an essential global resource for assessing the burden of preterm birth and developing public health programmes and policies. This protocol describes the methods ...
Joshua P. Vogel, Saifon Chawanpaiboon, Kanokwaroon Watananirun, Pisake Lumbiganon, Max Petzold, Ann-Beth Moller, Jadsada Thinkhamrop, Malinee Laopaiboon, Armando H. Seuc, Daniel Hogan, Ozge Tunçalp, Emma Allanson, Ana Pilar Betrán, Mercedes Bonet, Olufemi T. Oladapo and A. Metin Gülmezoglu
Reproductive Health 2016 13:76
Published on: 17 June 2016

Northeastern North America as a potential refugium for boreal forests in a warming climate

Science
17 June 2016 Vol 352, Issue 6292
http://www.sciencemag.org/current.dtl
Special Issue: Signals in RNA

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Northeastern North America as a potential refugium for boreal forests in a warming climate
By L. D’Orangeville, L. Duchesne, D. Houle, D. Kneeshaw, B. Côté, N. Pederson
Science17 Jun 2016 : 1452-1455
Tree-ring data from black spruce indicate increased growth in response to increased temperatures.
Editor’s Summary
A future for boreal forests
Conservation under climate change presents the challenge of predicting where will be suitable for particular organisms and ecological communities in the future. D’Orangeville et al. assess the probable future range for boreal forests in eastern North America, which are expected to be subject to large temperature increases in their natural range. Using tree-ring data from many thousands of forest stands, they delineate the geographical extent of the region where tree growth responds favorably to higher temperatures and where the forest should persist at least until 2070.

Toward a Realistic and Responsible Idea of Stabilisation

Stability: International Journal of Security & Development
http://www.stabilityjournal.org/articles
[accessed 18 June 2016]

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Research Article
Toward a Realistic and Responsible Idea of Stabilisation
Philipp Rotmann
15 Jun 2016
Abstract
What is stabilisation, and why do we need a conceptual discussion? Based on interviews and policy documents from Canada, Germany, the Netherlands, the United Kingdom and the United States, this article distils two conceptual visions of stabilisation, outlines a range of institutional and budgetary designs and offers a number of lessons of what a realistic and responsible idea of stabilisation might look like. Given the ubiquity of fragility and the lack of generalised knowledge about social engineering, this article argues in favour of a narrow understanding of stabilisation that seeks only to mitigate acute situations of crisis marked by extreme political volatility and violence. Even this more limited goal is ambitious enough to require sober assessment and communication of risk, continuing improvements to the conceptual and institutional tools for stabilisation and stronger commitment to constant reflection and learning.

The Sentinel

Human Rights Action :: Humanitarian Response :: Health :: Education :: Heritage Stewardship ::
Sustainable Development
__________________________________________________
Week ending 11 June 2016

This weekly digest is intended to aggregate and distill key content from a broad spectrum of practice domains and organization types including key agencies/IGOs, NGOs, governments, academic and research institutions, consortia and collaborations, foundations, and commercial organizations. We also monitor a spectrum of peer-reviewed journals and general media channels. The Sentinel’s geographic scope is global/regional but selected country-level content is included. We recognize that this spectrum/scope yields an indicative and not an exhaustive product. Comments and suggestions should be directed to:

David R. Curry
Editor &
Founding Managing Director
GE2P2 – Center for Governance, Evidence, Ethics, Policy, Practice
david.r.curry@ge2p2center.net

pdf version: The Sentinel_ week ending 11 June 2016

:: Journal Watch

:: Journal Watch

The Sentinel will track key peer-reviewed journals which address a broad range of interests in human rights, humanitarian response, health and development. It is not intended to be exhaustive. We will add to those monitored below as we encounter relevant content and upon recommendation from readers. We selectively provide full text of abstracts and other content but note that successful access to some of the articles and other content may require subscription or other access arrangement unique to the publisher. Please suggest additional journals you feel warrant coverage.

Mothers’ willingness to pay for HPV vaccines in Anambra state, Nigeria: a cross sectional contingent valuation study

BMC Cost Effectiveness and Resource Allocation
http://resource-allocation.biomedcentral.com/
(Accessed 11 June 2016)

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Research
Mothers’ willingness to pay for HPV vaccines in Anambra state, Nigeria: a cross sectional contingent valuation study
Ifeoma Blessing Umeh, Sunday Odunke Nduka and Obinna Ikechukwu Ekwunife
Published: 6 June 2016
Abstract
Background
Human papilloma virus (HPV) vaccination in Nigeria will require substantial financing due to high cost of HPV vaccine and inexistence of structures to support adolescent vaccination. Alternative sources are needed to sustain the government funded HPV vaccination programme. This study assessed Nigerian mothers’ willingness-to-pay (WTP) for HPV vaccine. We also compared the difference between the average WTP and estimated costs of vaccinating a pre-adolescent girl (CVG).
Methods
We conducted a quantitative, cross-sectional, survey-based study in which 50 questionnaires were distributed to each of 10 secondary schools located in two rural and one urban city in Anambra state. The questionnaires were then randomly distributed to girls aged 9–12 years of age to give to their mothers. Contingent valuation approach using the payment card technique was used to estimate the average maximum WTP among the survey participants. Correlates of WTP for HPV vaccination were obtained using multivariate logistic regression. Estimated CVG was obtained by adapting cost of HPV vaccine delivery in Tanzania to the Nigerian setting.
Results
A total of 438 questionnaires (88 %) were returned. The average WTP was US$ 11.68. This is opposed to estimated delivery cost of US$ 18.16 and US$ 19.26 for urban and rural populations respectively at vaccine price offered by the Vaccine Alliance (Gavi) and US$ 35.16 and US$ 36.26 for urban and rural populations respectively at the lowest obtainable public sector vaccine price. Demand for HPV vaccine was deemed high (91.6 %) and was significantly associated with respondents previously diagnosed of HPV infection.
Conclusion
Demand for HPV vaccine was high although short of estimated CVG. High demand for vaccine should be capitalized upon to increase vaccine uptake. Education on cervical cancer and provider-initiated vaccination should be promoted to increase vaccine uptake. Co-payment could be a feasible financing strategy in the event of national HPV vaccination.

BMC Infectious Diseases (Accessed 11 June 2016)

BMC Infectious Diseases

(Accessed 11 June 2016)

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Research article
A survey of tuberculosis infection control practices at the NIH/NIAID/DAIDS-supported clinical trial sites in low and middle income countries
Health care associated transmission of Mycobacterium tuberculosis (TB) is well described. A previous survey of infection control (IC) practices at clinical research sites in low and middle income countries (LMIC)…
Catherine Godfrey, Gail Tauscher, Sally Hunsberger, Melissa Austin, Lesley Scott, Jeffrey T. Schouten, Anne F. Luetkemeyer, Constance Benson, Robert Coombs and Susan Swindells
BMC Infectious Diseases 2016 16:269
Published on: 10 June 2016

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Research article
Global research trends of Middle East respiratory syndrome coronavirus: a bibliometric analysis
Middle East respiratory syndrome coronavirus (MERS-CoV) is a virus that causes severe viral pneumonia in humans, known to have a high mortality rate and a similarity in clinical symptoms with severe acute resp…
Sa’ed H. Zyoud
BMC Infectious Diseases 2016 16:255
Published on: 7 June 2016

BMC Medical Ethics (Accessed 11 June 2016)

BMC Medical Ethics
http://www.biomedcentral.com/bmcmedethics/content
(Accessed 11 June 2016)

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Research article
Steps toward improving ethical evaluation in health technology assessment: a proposed framework
While evaluation of ethical aspects in health technology assessment (HTA) has gained much attention during the past years, the integration of ethics in HTA practice still presents many challenges. In response …
Nazila Assasi, Jean-Eric Tarride, Daria O’Reilly and Lisa Schwartz
BMC Medical Ethics 2016 17:34
Published on: 6 June 2016

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Debate
Citizen science or scientific citizenship? Disentangling the uses of public engagement rhetoric in national research initiatives
The language of “participant-driven research,” “crowdsourcing” and “citizen science” is increasingly being used to encourage the public to become involved in research ventures as both subjects and scientists. …
J. Patrick Woolley, Michelle L. McGowan, Harriet J. A. Teare, Victoria Coathup, Jennifer R. Fishman, Richard A. Settersten, Sigrid Sterckx, Jane Kaye and Eric T. Juengst
BMC Medical Ethics 2016 17:33
Published on: 4 June 2016