A scoping review of video gaming in rehabilitation

Disability and Rehabilitation: Assistive Technology
Volume 11, Issue 6, 2016
http://informahealthcare.com/toc/idt/current

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Review Article
A scoping review of video gaming in rehabilitation
pages 445-453
DOI:10.3109/17483107.2015.1029538
Kelly E. Ravenek, Dalton L. Wolfe & Sander L. Hitzig
Abstract
Purpose: To examine the scope of the peer-reviewed literature on the use of commercially available video gaming in rehabilitation. Methods: Five databases (SCOPUS, Cochrane, PsycINFO, PubMed and CINAHL) were searched for articles published between January 1990 and January 2014. The reference lists of selected articles were also reviewed to identify other relevant studies. Results: Thirty articles met the inclusion criteria. Commercially available video gaming in rehabilitation was most commonly recommended by physiotherapists (50% or 15/30 studies) for populations at risk for falls or with decreased balance (67% or 19/30 studies). The most commonly used target outcomes were those assessing balance and/or fall prevention, with the Berg Balance Scale being the most frequently used (53% or 16/30 studies) outcome measure. The Nintendo Wii was the most prevalent gaming system (90% or 27/30 studies) used in the identified studies. Conclusion: Video gaming in rehabilitation is widely used by clinicians. Preliminary findings show that video gaming technology can be applied across a wide variety of rehabilitation populations, with some evidence showing clinical gains in physical functioning (e.g. gait and balance). There is a need for more robust clinical trials evaluating the efficacy of using video game systems as an adjunct to conventional rehabilitation.

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Implications for Rehabilitation
:: Video gaming is a readily available technology that has been suggested as an enjoyable and motivating activity that engages patients in rehabilitation programming.
:: Video gaming is becoming an increasingly popular adjunct to traditional therapy.
:: Video gaming is most commonly used by physical therapists in a hospital setting for those with balance impairments.
:: Video gaming has been shown to improve functional outcomes.

Health Policy and Planning – Volume 31 Issue 6 July 2016

Health Policy and Planning
Volume 31 Issue 6 July 2016
http://heapol.oxfordjournals.org/content/current

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Original Articles
The emergence of the vertical birth in Ecuador: an analysis of agenda setting and policy windows for intercultural health
Ana Llamas and Susannah Mayhew
Health Policy Plan. (2016) 31 (6): 683-690 doi:10.1093/heapol/czv118
Abstract
Maternal mortality continues to claim the lives of thousands of women in Latin America despite the availability of effective treatments to avert maternal death. In the past, efforts to acknowledge cultural diversity in birth practices had not been clearly integrated into policy. However, in Otavalo (Ecuador) a local hospital pioneered the implementation of the ‘Vertical Birth’—a practical manifestation of an intercultural health policy aimed at increasing indigenous women’s access to maternity care. Drawing on agenda-setting theory, this qualitative research explores how the vertical birth practice made it onto the local policy agenda and the processes that allowed actors to seize a window of opportunity allowing the vertical birth practice to emerge. Our results show that the processes that brought about the vertical birth practice took place over a prolonged period of time and resulted from the interplay between various factors. Firstly, a maternal health policy community involving indigenous actors played a key role in identifying maternal mortality as a policy problem, defining its causes and framing it as an indigenous rights issue. Secondly, previous initiatives to address maternal mortality provided a wealth of experience that gave these actors the knowledge and experience to formulate a feasible policy solution and consolidate support from powerful actors. Thirdly, the election of a new government that had incorporated the demands of the indigenous movement opened up a window of opportunity to push intercultural health policies such as the vertical birth. We conclude that the socioeconomic and political changes at both national and local level allowed the meaningful participation of indigenous actors that made a critical contribution to the emergence of the vertical birth practice. These findings can help us advance our knowledge of strategies to set the agenda for intercultural maternal health policy and inform future policy in similar settings. Our results also show that Kingdon’s model was useful in explaining how the VB practice emerged but also that it needs modifications when applied to low and middle income countries.

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Original Articles
Feasibility and acceptability of delivering adolescent health interventions alongside HPV vaccination in Tanzania
Deborah Watson-Jones, Shelley Lees, Joseph Mwanga, Nyasule Neke, John Changalucha, Nathalie Broutet, Ibrahim Maduhu, Saidi Kapiga, Venkatraman Chandra-Mouli, Paul Bloem,
and David A Ross
Health Policy Plan. (2016) 31 (6): 691-699 doi:10.1093/heapol/czv119
Abstract
Background: Human papillomavirus (HPV) vaccination offers an opportunity to strengthen provision of adolescent health interventions (AHI). We explored the feasibility of integrating other AHI with HPV vaccination in Tanzania.
Methods: A desk review of 39 policy documents was preceded by a stakeholder meeting with 38 policy makers and partners. Eighteen key informant interviews (KIIs) with health and education policy makers and district officials were conducted to further explore perceptions of current programs, priorities and AHI that might be suitable for integration with HPV vaccination.
Results: Fourteen school health interventions (SHI) or AHI are currently being implemented by the Government of Tanzania. Most are delivered as vertical programmes. Coverage of current programs is not universal, and is limited by financial, human resource and logistic constraints. Limited community engagement, rumours, and lack of strategic advocacy has affected uptake of some interventions, e.g. tetanus toxoid (TT) immunization. Stakeholder and KI perceptions and opinions were limited by a lack of experience with integrated delivery and AHI that were outside an individual’s area of expertise and experience. Deworming and educational sessions including reproductive health education were the most frequently mentioned interventions that respondents considered suitable for integrated delivery with HPV vaccine.
Conclusions: Given programme constraints, limited experience with integrated delivery and concern about real or perceived side-effects being attributed to the vaccine, it will be very important to pilot-test integration of AHI/SHI with HPV vaccination. Selected interventions will need to be simple and quick to deliver since health workers are likely to face significant logistic and time constraints during vaccination visits.

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Editor’s Choice:
BRICS countries and the global movement for universal health coverage
Fabrizio Tediosi, Aureliano Finch, Christina Procacci, Robert Marten, and Eduardo Missoni
Health Policy Plan. (2016) 31 (6): 717-728 doi:10.1093/heapol/czv122
Abstract
This article explores BRICS’ engagement in the global movement for Universal Health Coverage (UHC) and the implications for global health governance. It is based on primary data collected from 43 key informant interviews, complemented by a review of BRICS’ global commitments supporting UHC. Interviews were conducted using a semi-structured questionnaire that included both closed- and open-ended questions. Question development was informed by insights from the literature on UHC, Cox’s framework for action, and Kingdon’s multiple-stream theory of policy formation. The closed questions were analysed with simple descriptive statistics and the open-ended questions using grounded theory approach. The analysis demonstrates that most BRICS countries implicitly supported the global movement for UHC, and that they share an active engagement in promoting UHC. However, only Brazil, China and to some extent South Africa, were recognized as proactively pushing UHC in the global agenda. In addition, despite some concerted actions, BRICS countries seem to act more as individual countries rather that as an allied group. These findings suggest that BRICS are unlikely to be a unified political block that will transform global health governance. Yet the documented involvement of BRICS in the global movement supporting UHC, and their focus on domestic challenges, shows that BRICS individually are increasingly influential players in global health. So if BRICS countries should probably not be portrayed as the centre of future political community that will transform global health governance, their individual involvement in global health, and their documented concerted actions, may give greater voice to low- and middle-income countries supporting the emergence of multiple centres of powers in global health.

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Review
Framing and the health policy process: a scoping review
Adam D Koon, Benjamin Hawkins, and Susannah H Mayhew
Health Policy Plan. (2016) 31 (6): 801-816 doi:10.1093/heapol/czv128
Abstract
Framing research seeks to understand the forces that shape human behaviour in the policy process. It assumes that policy is a social construct and can be cast in a variety of ways to imply multiple legitimate value considerations. Frames provide the cognitive means of making sense of the social world, but discordance among them forms the basis of policy contestation. Framing, as both theory and method, has proven to generate considerable insight into the nature of policy debates in a variety of disciplines. Despite its salience for understanding health policy debates; however, little is known about the ways frames influence the health policy process. A scoping review using the Arksey and O’Malley framework was conducted. The literature on framing in the health sector was reviewed using nine health and social science databases. Articles were included that explicitly reported theory and methods used, data source(s), at least one frame, frame sponsor and evidence of a given frame’s effect on the health policy process. A total of 52 articles, from 1996 to 2014, and representing 12 countries, were identified. Much of the research came from the policy studies/political science literature (n = 17) and used a constructivist epistemology. The term ‘frame’ was used as a label to describe a variety of ideas, packaged as values, social problems, metaphors or arguments. Frames were characterized at various levels of abstraction ranging from general ideological orientations to specific policy positions. Most articles presented multiple frames and showed how actors advocated for them in a highly contested political process. Framing is increasingly an important, yet overlooked aspect of the policy process. Further analysis on frames, framing processes and frame conflict can help researchers and policymakers to understand opaque and highly charged policy issues, which may facilitate the resolution of protracted policy controversies.

Health Research Policy and Systems [Accessed 23 July 2016]

Health Research Policy and Systems
http://www.health-policy-systems.com/content
[Accessed 23 July 2016]

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Research
Embedding research in health systems: lessons from complexity theory
Internationally, there has been increasing focus on creating health research systems. This article aims to investigate the challenges of implementing apparently simple strategies to support the development of …
Louise Caffrey, Charles Wolfe and Christopher McKevitt
Health Research Policy and Systems 2016 14:54
Published on: 22 July 2016

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Research
Developing the African national health research systems barometer
A functional national health research system (NHRS) is crucial in strengthening a country’s health system to promote, restore and maintain the health status of its population. Progress towards the goal of univ...
Joses Muthuri Kirigia, Martin Okechukwu Ota, Flavia Senkubuge, Charles Shey Wiysonge and Bongani M. Mayosi
Health Research Policy and Systems 2016 14:53
Published on: 22 July 2016

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Commentary
A global call for action to include gender in research impact assessment
Global investment in biomedical research has grown significantly over the last decades, reaching approximately a quarter of a trillion US dollars in 2010. However, not all of this investment is distributed eve…
Pavel V. Ovseiko, Trisha Greenhalgh, Paula Adam, Jonathan Grant, Saba Hinrichs-Krapels, Kathryn E. Graham, Pamela A. Valentine, Omar Sued, Omar F. Boukhris, Nada M. Al Olaqi, Idrees S. Al Rahbi, Anne-Maree Dowd, Sara Bice, Tamika L. Heiden, Michael D. Fischer, Sue Dopson…
Health Research Policy and Systems 2016 14:50
Published on: 19 July 2016

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Research
Health systems research in fragile and conflict-affected states: a research agenda-setting exercise
There is increasing interest amongst donors in investing in the health sectors of fragile and conflict-affected states, although there is limited research evidence and research funding to support this. Agreein…
Aniek Woodward, Egbert Sondorp, Sophie Witter and Tim Martineau
Health Research Policy and Systems 2016 14:51
Published on: 21 July 2016

The Lancet – Jul 23, 2016

The Lancet
Jul 23, 2016 Volume 388 Number 10042 p307-436
http://www.thelancet.com/journals/lancet/issue/current

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Articles
The burden of mental, neurological, and substance use disorders in China and India: a systematic analysis of community representative epidemiological studies
Fiona J Charlson, Amanda J Baxter, Hui G Cheng, Rahul Shidhaye, Harvey A Whiteford
Summary
Background
China and India jointly account for 38% of the world population, so understanding the burden attributed to mental, neurological, and substance use disorders within these two countries is essential. As part of the Lancet/Lancet Psychiatry China–India Mental Health Alliance Series, we aim to provide estimates of the burden of mental, neurological, and substance use disorders for China and India from the Global Burden of Disease Study 2013 (GBD 2013).
Methods
In this systematic analysis for community representative epidemiological studies, we conducted systematic reviews in line with PRISMA guidelines for community representative epidemiological studies. We extracted estimates of prevalence, incidence, remission and duration, and mortality along with associated uncertainty intervals from GBD 2013. Using these data as primary inputs, DisMod-MR 2.0, a Bayesian meta-regression instrument, used a log rate and incidence-prevalence-mortality mathematical model to develop internally consistent epidemiological models. Disability-adjusted life-year (DALY) changes between 1990 and 2013 were decomposed to quantify change attributable to population growth and ageing. We projected DALYs from 2013 to 2025 for mental, neurological, and substance use disorders using United Nations population data.
Findings
Around a third of global DALYs attributable to mental, neurological, and substance use disorders were found in China and India (66 million DALYs), a number greater than all developed countries combined (50 million DALYs). Disease burden profiles differed; India showed similarities with other developing countries (around 50% of DALYs attributable to non-communicable disease), whereas China more closely resembled developed countries (around 80% of DALYs attributable to non-communicable disease). The overall population growth in India explains a greater proportion of the increase in mental, neurological, and substance use disorder burden from 1990 to 2013 (44%) than in China (20%). The burden of mental, neurological, and substance use disorders is estimated to increase by 10% in China and 23% in India between 2013 and 2025.
Interpretation
The current and projected burden of mental, neurological, and substance use disorders in China and India warrants the urgent prioritisation of programmes focused on targeted prevention, early identification, and effective treatment.
Funding
China Medical Board, Bill & Melinda Gates Foundation.
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Series
Transgender health
Transgender people: health at the margins of society
Sam Winter, Milton Diamond, Jamison Green, Dan Karasic, Terry Reed, Stephen Whittle, Kevan Wylie

Transgender health
Serving transgender people: clinical care considerations and service delivery models in transgender health
Kevan Wylie, Gail Knudson, Sharful Islam Khan, Mireille Bonierbale, Suporn Watanyusakul, Stefan Baral

Transgender health
Global health burden and needs of transgender populations: a review
Sari L Reisner, Tonia Poteat, JoAnne Keatley, Mauro Cabral, Tampose Mothopeng, Emilia Dunham, Claire E Holland, Ryan Max, Stefan D Baral

Beyond the Ebola Battle — Winning the War against Future Epidemics

New England Journal of Medicine
July 21, 2016 Vol. 375 No. 3
http://www.nejm.org/toc/nejm/medical-journal
Perspective
Beyond the Ebola Battle — Winning the War against Future Epidemics
Victor J. Dzau, M.D., and Peter Sands, M.P.A.
N Engl J Med 2016; 375:203-204 July 21, 2016 DOI: 10.1056/NEJMp1605847
[Initial text]
The battle to contain and ultimately defeat the Ebola epidemic of 2014–2015 has been vividly described.1-3 Caught off guard from the start and hindered by myriad coordination, communication, and other problems, a combination of local and international teams fought back with determination, courage, and eventually the deployment of substantial resources to stem the contagion and save lives. Yet more than 11,000 people died, and local economies were brought to a halt. The battle was won, but at immense cost.

With the immediate crisis over, the world’s attention has moved on. Ebola has vanished from the headlines and seemingly from policymakers’ to-do lists. Attention has shifted to Zika and other competing priorities. Yet it would be a huge mistake to turn away and declare the war over, for West Africa remains vulnerable to a resurgence of Ebola. There will undoubtedly be new outbreaks; the only question is how well they will be contained…

Women’s Education and Health Inequalities in Under-Five Mortality in Selected Sub-Saharan African Countries, 1990–2015

PLoS One
http://www.plosone.org/
[Accessed 23 July 2016]

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Research Article
Women’s Education and Health Inequalities in Under-Five Mortality in Selected Sub-Saharan African Countries, 1990–2015
Aristide Romaric Bado, A. Sathiya Susuman
Research Article | published 21 Jul 2016 | PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0159186
Abstract
Background
The aim of the study was to analyse trends in the relationship between mother’s educational level and mortality of children under the year of five in Sub-Saharan Africa, from 1990 to 2015.
Data and Methods
Data used in this study came from different waves of Demographic and Health Surveys (DHS) of Sub-Saharan countries. Logistic regression and Buis’s decomposition method were used to explore the effect of mother’s educational level on the mortality of children under five years.
Results
Although the results of our study in the selected countries show that under-five mortality rates of children born to mothers without formal education are higher than the mortality rates of children of educated mothers, it appears that differences in mortality were reduced over the past two decades. In selected countries for our study, we noticed a significant decline in mortality among children of non-educated mothers compared to the decrease in mortality rates among children of educated mothers during the period of 1990–2010. The results show that the decline in mortality of children under five years was much higher among the children born to mothers who have never received formal education—112 points drop in Malawi, over 80 in Zambia and Zimbabwe, 65 points in Burkina Faso, 56 in Congo, 43 in Namibia, 27 in Guinea, Cameroon, and 22 to 15 in Niger. However, we noted a variation in results among the countries selected for the study—in Burkina Faso (OR = 0.7), in Cameroon (OR = 0.8), in Guinea (OR = 0.8) and Niger (OR = 0.8). It is normally observed that children of mothers with 0–6 years of education are about 20% more likely to survive until their fifth year compared to children of mothers who have not been to school. Conversely, the results did not reveal significant differences between the under-five deaths of children born to non-educated mothers and children of low-level educated mothers in Congo, Malawi and Namibia.
Conclusion
The decline in under-five mortality rates, during last two decades, can be partly due to the government policies on women’s education. It is evident that women’s educational level has resulted in increased maternal awareness about infant health and hygiene, thereby bringing about a decline in the under-five mortality rates. This reduction is due to improved supply of health care programmes and health policies in reducing economic inequalities and increasing access to health care.

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Research Article |
Assessing Progress, Impact, and Next Steps in Rolling Out Voluntary Medical Male Circumcision for HIV Prevention in 14 Priority Countries in Eastern and Southern Africa through 2014
Katharine Kripke, Emmanuel Njeuhmeli, Julia Samuelson, Melissa Schnure, Shona Dalal, Timothy Farley, Catherine Hankins, Anne G. Thomas, Jason Reed, Peter Stegman, Naomi Bock
published 21 Jul 2016 | PLOS ONE
http://dx.doi.org/10.1371/journal.pone.0158767

The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease

PLoS Pathogens
http://journals.plos.org/plospathogens/
(Accessed 23 July 2016)

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Pearls
The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease
Kelly J. Pittman, Luke C. Glover, Liuyang Wang, Dennis C. Ko
| published 21 Jul 2016 | PLOS Pathogens
http://dx.doi.org/10.1371/journal.ppat.1005680
[Initial text]
For millennia, pathogens and human hosts have engaged in a perpetual struggle for supremacy. From the earliest recorded smallpox epidemics around 1350 B.C.E to the Black Death due to Yersinia pestis in the Middle Ages and continuing to modern times with HIV, there has been a continuous clash between pathogens and human hosts. But past pandemics are more than just ancient history—they are drivers of human genetic diversity and natural selection. Pathogens can dramatically decrease survival and reproductive potential, leading to selection for resistance alleles and elimination of susceptibility alleles. Despite this persistent struggle between host and pathogen, only in the past century have we developed an understanding of some of the human genetic differences that regulate infectious disease susceptibility and severity…

Growth mindset tempers the effects of poverty on academic achievement

PNAS – Proceedings of the National Academy of Sciences of the United States of America
http://www.pnas.org/content/early/
(Accessed 23 July 2016)

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Social Sciences – Psychological and Cognitive Sciences:
Growth mindset tempers the effects of poverty on academic achievement
Susana Claroa,1, David Pauneskub, and Carol S. Dweckb,1
Significance
This study is the first, to our knowledge, to show that a growth mindset (the belief that intelligence is not fixed and can be developed) reliably predicts achievement across a national sample of students, including virtually all of the schools and socioeconomic strata in Chile. It also explores the relationship between income and mindset for the first time, to our knowledge, finding that students from lower-income families were less likely to hold a growth mindset than their wealthier peers but that those who did hold a growth mindset were appreciably buffered against the deleterious effects of poverty on achievement. These results suggest that mindsets may be one mechanism through which economic disadvantage can affect achievement.
Abstract
Two largely separate bodies of empirical research have shown that academic achievement is influenced by structural factors, such as socioeconomic background, and psychological factors, such as students’ beliefs about their abilities. In this research, we use a nationwide sample of high school students from Chile to investigate how these factors interact on a systemic level. Confirming prior research, we find that family income is a strong predictor of achievement. Extending prior research, we find that a growth mindset (the belief that intelligence is not fixed and can be developed) is a comparably strong predictor of achievement and that it exhibits a positive relationship with achievement across all of the socioeconomic strata in the country. Furthermore, we find that students from lower-income families were less likely to hold a growth mindset than their wealthier peers, but those who did hold a growth mindset were appreciably buffered against the deleterious effects of poverty on achievement: students in the lowest 10th percentile of family income who exhibited a growth mindset showed academic performance as high as that of fixed mindset students from the 80th income percentile. These results suggest that students’ mindsets may temper or exacerbate the effects of economic disadvantage on a systemic level.

Ecological disruption precedes mass extinction

PNAS – Proceedings of the National Academy of Sciences of the United States of America
http://www.pnas.org/content/early/
(Accessed 23 July 2016)

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Commentary
Ecological disruption precedes mass extinction
Steven M. Hollanda,1
[Initial text]
Mass extinctions are dramatic features of the fossil record in which extinction risk is substantially elevated above background levels. Although extinction risk varies markedly over geologic time, as well as geographically, it was particularly elevated and global in extent during the so-called Big Five events: the Late Ordovician, Late Devonian, end-Permian, end-Triassic, and end-Cretaceous (1). These events were originally recognized by variations in extinction rate in marine animal families, and their importance remains in analyses at the genus level and that account for variable preservation over geologic time (2, 3). Increasing attention has concentrated on understanding the ecological effects of mass extinction and other lesser but still significant extinction episodes (4⇓⇓⇓⇓⇓–10). In PNAS, Sheets et al. (11) document the ecological changes in marine planktonic communities not only during, but preceding the Late Ordovician (447–444 Ma) mass extinction.

Examining the ecological changes during a mass extinction would seem to be straightforward: go to a stratigraphic column spanning the mass extinction and describe the changing ecological composition of successive sedimentary layers through the extinction episode. This would be a direct history of ecological changes related to the extinction if those layers recorded the same habitat through time, such as the distance from shore or water depth for marine benthic organisms, or the overlying water masses for marine plankton. Unfortunately, this simple scenario is rarely the case, as numerous studies of sedimentation over the past 40 y have shown (12). Processes of sediment accumulation create two challenges for studying ancient mass extinctions (13).

Healthcare access and quality of birth care: narratives of women living with obstetric fistula in rural Tanzania

Reproductive Health
http://www.reproductive-health-journal.com/content
[Accessed 23 July 2016]
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Research
Healthcare access and quality of birth care: narratives of women living with obstetric fistula in rural Tanzania
Increasing births with skilled attendants and increasing health facilities with Emergency Obstetric Care (EmOC) can reduce maternal mortality and are considered critical interventions for ensuring safe motherh…
Lilian T. Mselle and Thecla W. Kohi
Reproductive Health 2016 13:87
Published on: 22 July 2016

Special Issue: Strengthening of Regulatory Systems for Medicines in the Americas

Revista Panamericana de Salud Pública/Pan American Journal of Public Health (RPSP/PAJPH)
June 2016
http://www.paho.org/journal/

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Special Issue: Strengthening of Regulatory Systems for Medicines in the Americas
Health regulation is regarded as one of public health’s basic functions. Effective regulation of medicines promotes and protects the public’s health by guaranteeing medicines quality, safety, and efficacy; promoting the adequate manufacture, storage, and distribution of medicines; facilitating the fight against substandard, spurious, falsely-labeled, falsified, or counterfeit (SSFFC) medical products; providing the necessary information to health professionals and patients so they can use medicines rationally; and ensuring that access to medicines is not hindered by inefficient regulatory frameworks. Developing a national regulatory system is, hence, a critical component of a national health system.
This special issue of the Pan American Journal of Public Health was a joint project supported by the US Food and Drug Administration. The issue comprises 14 original peer reviewed research articles that highlight the progress and remaining challenges that the Region faces in ensuring access to safe, efficacious and quality-assured medical products.
[Series of articles]

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Strengthening of regulatory systems for medicines in the Americas
Etienne, Carissa F. Califf, Robert
Abstract
Health regulation is regarded as one of public health’s basic functions. Effective regulation of medicines promotes and protects the public’s health by guaranteeing medicines quality, safety, and efficacy; promoting the adequate manufacture, storage, and distribution of medicines; facilitating the fight against substandard, spurious, falsely labeled, falsified, or counterfeit medical products; providing the necessary information to health professionals and patients so they can use medicines rationally; and ensuring that access to medicines is not hindered by inefficient regulatory frameworks. Developing a strong national regulatory system is, therefore, a critical component of a national health system. In this context, we are pleased to present the first ever special issue of the Pan American Journal of Public Health to focus on strengthening of regulatory systems for medicines and other technologies. This special issue is an expression of the resolve of the governments of the Americas in implementing the Pan American Health Organization Directing Council Resolution CD50.R9 (2010) “Strengthening National Regulatory Authorities for Medicines and Biologicals,” and more recently of the Member States of the World Health Organization in the adoption of resolution WHA67.20 (2014), “Regulatory system strengthening for medical products.”…The journal brings together articles from regulatory experts within the Region of the Americas as well as from global experts, who bring an array of experiences to the fore. They present the essential underpinning of science and regulation that bring life-saving and innovative products to the marketplace; analysis of key contributions from international fora and public-private coalitions that can add to regulatory science and the development of good regulatory practices; and the ever-evolving challenges that regulators face to build inter-linked and convergent regulatory systems within the context of limited capacity, human and financial resources, nationally and globally.

Countering the Zika epidemic in Latin America

Science
22 July 2016 Vol 353, Issue 6297
http://www.sciencemag.org/current.dtl

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Policy Forum
Countering the Zika epidemic in Latin America
By Neil M. Ferguson, Zulma M. Cucunubá, Ilaria Dorigatti, Gemma L. Nedjati-Gilani, Christl A. Donnelly, Maria-Gloria Basáñez, Pierre Nouvellet, Justin Lessler
Science22 Jul 2016 : 353-354
Epidemic dynamics are key and data gaps must be addressed
Summary
As evidence grew for a causal link between Zika infection and microcephaly and other serious congenital anomalies (1), the World Health Organization (WHO) declared the Latin American Zika epidemic a public health emergency of international concern in February 2016 (2). The speed of spread [see the figure, top, and the supplementary materials (SM)] has made effective public health responses challenging. Immediate responses have included vector control (3) and advice to delay pregnancy in a few countries (4), followed by an extended recommendation to all affected countries by WHO in June 2016. These have merits but are likely to have limited effectiveness (5) and may interact antagonistically. Fuller understanding of dynamics and drivers of the epidemic is needed to assess longer-term risks to prioritize interventions.

Understanding global health and development partnerships: Perspectives from African and global health system professionals

Social Science & Medicine
Volume 159, Pages 1-180 (June 2016)
http://www.sciencedirect.com/science/journal/02779536/156

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Review articles
Understanding global health and development partnerships: Perspectives from African and global health system professionals
Original Research Article
Pages 22-29
Amy Barnes, Garrett W. Brown, Sophie Harman
Abstract
Partnership is a key idea in current debates about global health and development assistance, yet little is known about what partnership means to those who are responsible for operationalising it or how it is experienced in practice. This is particularly the case in the context of African health systems. This paper explores how health professionals working in global health hubs and the health systems of South Africa, Tanzania and Zambia understand and experience partnership. Drawing on semi-structured interviews with 101 professionals based in each country, Washington DC and Geneva between October 2012 and June 2013, the paper makes four key arguments. First, partnership has a legitimating function in global health policy processes for international development institutions, government agencies and civil society organisations alike. Second, the practice of partnership generates idiosyncratic and complicated relationships that health professionals have to manage and navigate, often informally. Third, partnership is shaped by historical legacies, critical events, and independent consultants. Fourth, despite being an accepted part of global health policy, there is little shared understanding of what good partnership is meant to include or resemble in practice. Knowing more about the specific socio-cultural and political dynamics of partnership in different health system contexts is critical to equip health professionals with the skills to build the informal relations that are essential to effective partnership engagement.

Beating the odds: Successful establishment of a Phase II/III clinical research trial in resource-poor Liberia during the largest-ever Ebola outbreak

Contemporary Clinical Trials Communications
Available online 24 June 2016
Beating the odds: Successful establishment of a Phase II/III clinical research trial in resource-poor Liberia during the largest-ever Ebola outbreak
In Press, Accepted Manuscript – Open Access
J. Doe-Andersona, B. Baselera, P. Driscollb, M. Johnsonc, J. Lysanderc, L. McNayd, W.S. Njoha, M. Smolskisd, L. Wehrlene, J. Zuckermand, for the PREVAIL I Study Group
Abstract
It has been argued that a country such as Liberia, not fully recovered from the devastation of decades of civil unrest, lacked the appropriate ethical and regulatory framework, basic human and health care services, and infrastructure to carry out clinical trials according to international standards of quality during a public health emergency. However, as Liberia, Sierra Leone, and Guinea were being ravaged by the largest and most devastating Ebola Virus Disease (EVD) outbreak ever recorded, the topic of conducting clinical trials of experimental vaccine and treatment candidates in these resource-poor countries generated the keen interest and concern of scientists, researchers, physicians, bioethicists, philanthropists, and even politicians. Decisive action on behalf of the Liberian government, and a timely positive and supportive response from the United States (U.S.) government, led to the formation of PREVAIL (Partnership for Research on Ebola Vaccines in Liberia) – a clinical research partnership between the two governments. Within a span of 12 weeks, this partnership accomplished the unimaginable: the successful initiation of a Phase II/III vaccine clinical trial for EVD in Liberia. This paper will discuss the dynamics of the research collaboration, barriers encountered, breakthroughs realized, key elements of success, and lessons learned in the process.

African Cultural Heritage Conservation and Management: Theory and Practice

African Cultural Heritage Conservation and Management: Theory and Practice
Susan Osireditse Keitumetse
[Book] Springer International Publishing
2016
DOI: 10.1007/978-3-319-32017-5_1
Print ISBN: 978-3-319-32015-1
Online ISBN: 978-3-319-32017-5
Abstract
This book seeks to place African cultural heritage studies and conservation practices in the modern context by bringing out modern topics around its use in the contemporary world. Cultural heritage resources in Africa and the developing world are facing a challenge of being roped into multiple platforms in a reactive and/or haphazard manner that does not account for their sustainable use. General resources conservation has been taking place in multiple facets for time immemorial. Cultural heritage resources management field, however, is new in Africa and among African stakeholders. Cultural heritage resources management is a process of organising the use of cultural resources amongst multiple stakeholders such as people, institutions, governments, regions and the world. To organise cultural resources conservation ideas, a conceptual framework (theory) built from observed stakeholders’ relationship with the resources (practice) through time, is needed. This chapter introduces the book’s consolidated and coordinated point of departure into theory and practice for African cultural heritage management. It also introduces an underlying make-up of contents in the book on African cultural heritage conservation and management. The book features a variety of topics through its chapters, amongst them international conventions as frameworks for African cultural heritage management, politics of the past, the building of sustainable communities using cultural heritage, sustainable interpretation of heritage , standard setting (certification) and heritage, heritage tourism and development mainstreaming of cultural heritage in Africa.

Constructive conservation – a model for developing heritage assets

Journal of Cultural Heritage Management and Sustainable Development
ISSN: 2044-1266
Volume 6 Issue 1
http://www.emeraldinsight.com/toc/jchmsd/6/1

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Conceptual Paper
Constructive conservation – a model for developing heritage assets
Sarah Hill (Independent Consultant, Toronto, Canada AND Lord Cultural Resources, Toronto, Canada)
Abstract
Purpose
– The purpose of this paper is to outline a conceptual model for adaptive reuse of heritage assets which has been produced in an effort to fill a gap in information, address the complexity of developing heritage assets and encourage more responsible and responsive treatment of heritage assets. The purpose of the model is to visually articulate the various elements that must be considered to successfully develop a heritage asset.
Design/methodology/approach
– Based on six years of observation and industry practice, the model reflects a previously undocumented process for developing and adapting built heritage assets employed by many professionals across the UK. The model is further strengthened by drawing from other international theories, concepts, and principles.
Findings
– The redevelopment of heritage assets is a “wicked problem”. The model established visually articulates current good practice in the field and provides a simplified version of the process.
Originality/value
– Presently, there is insufficient contemporary literature which adequately describes or visualizes the complex adaptive reuse of built heritage in a coherent and holistic way. This model is the first to try to visually capture and communicate current good practice for widespread use. It is hoped that the documentation and dissemination of this process will help to advance creative problem solving, increase the appeal of developing heritage assets and elevate the quality of work produced.

Data hubris? Humanitarian information systems and the mirage of technology

Third World Quarterly
Volume 37, Issue 8, 2016

Original Articles
Data hubris? Humanitarian information systems and the mirage of technology
Róisín Read, Bertrand Taithe and Roger Mac Ginty
Humanitarian and Conflict Response Institute, University of Manchester, UK
Free access DOI: 10.1080/01436597.2015.1136208
Abstract
This article looks at the promise of technology to revolutionise humanitarian action, especially in terms of the gathering and use of data. With many heralding a ‘data revolution’, the opportunities and enthusiasm for using social media and SMS data in crisis response are on the rise. The article constructs an analytical framework in order to scrutinise the three main claims made on behalf of technologically advanced humanitarian information systems: that they can access data more accurately, more quickly, and alter power relations in emancipatory ways. It does so in relation to two aspects of digital humanitarianism: visual technology and crisis mapping, and big data. The article is partly informed by a historical perspective, but also by interview and other material that suggests some of the claims made on behalf of technology are exaggerated. In particular, we argue that the enthusiasm for the data is vastly outstripped by the capacity to meaningfully analyse it. We conclude by scoping the implications of the future technological evolution of humanitarianism, in particular by examining how technology contributes to what Duffield terms ‘post-modern humanitarianism’.

Negotiating Knowledge – Evidence and experience in development NGOs

Negotiating Knowledge – Evidence and experience in development NGOs
Monograph – Published: July 2016 Pages: 180
Editors Rachel Hayman, Sophie King, Tiina Kontinen and Lata Narayanaswamy
eISBN: 978-1-78044-925-8 | ISBN: 978-1-85339-926-8
DOI: http://dx.doi.org/10.3362/9781780449258
Abstract
International NGOs are increasingly under pressure from governments and the public to demonstrate evidence of impact and positive results. This book critically examines how development NGOs working around the world create knowledge and evidence, and use it to satisfy donors, to improve their practices, and to further our understanding of poverty. It asks questions such as: does the evidence of community organizations count as much as higher-level organizations? Should southern NGOs be expected to disseminate pre-formed development ‘messages’? What do we mean by ‘evidence-based advocacy’?

The eight studies that form the core of Negotiating Knowledge span scholarly and practitioner research across Africa, Asia and Latin America. They tackle political issues that determine what forms of evidence and knowledge are given credence. They explore the power dynamics that shape the value placed on knowledge and learning in relationships within and between organizations.
Negotiating Knowledge urges NGOs to examine how they use knowledge in order to make it work better for themselves and for the people that they aim to assist. To do this well, they have to understand better what they mean by knowledge and evidence, revisit the value that they place on learning and knowledge, and invest in appropriate capacity and skills.

This book is essential reading for international NGO staff, policy makers, as well as those researching, studying and making policy in international development.

Health service utilization and access to medicines among Syrian refugee and host community children in Lebanon

Journal of International Humanitarian Action
December 2016, 1:10
http://link.springer.com/journal/41018/1/1/page/1

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Research Article
Health service utilization and access to medicines among Syrian refugee and host community children in Lebanon
Open Access First Online: 16 July 2016
Emily Lyles, Baptiste Hanquart, the LHAS Study Team, Michael Woodman, Shannon Doocy
DOI: 10.1186/s41018-016-0010-z
Abstract
Background
With over 500,000 Syrian refugee children in Lebanon, we undertook this study to assess unmet child health needs and health service utilization among Syrian refugees and affected host communities in Lebanon with the aim of informing humanitarian programming.
Methods
A cross-sectional survey of Syrian refugees and host communities in Lebanon was conducted using a two-stage cluster survey design with probability proportional to size sampling. The questionnaire focused on access to health services, including a module on care seeking for children.
Results
The care seeking rate was 74.2 % among refugee and 89.0 % among host community households with a child less than 18 years seeking medical care the last time it was needed. Refugee households most often sought care in primary health care centers (52.7 %), followed by pharmacies (22.2 %) and private clinics (17.8 %), whereas host community households most often sought care in private clinics (47.6 %) and primary health care centers (23.2 %). Among child care seekers, 95.2 % of refugee and 94.6 % of host community children were prescribed medication during the most recent visit, of which 92.7 and 97.3 %, respectively, obtained the medication. Overall, 66.0 % of refugee and 75.9 % of host community households reported out-of-pocket expenditures for either the consultation or prescribed medications at the most recent visit (refugee mean US$30.4; host community mean US$56.0).
Conclusions
Care seeking was significantly lower among refugees than the host community. Out-of-pocket payments were considerable for both groups, the majority of which were for medication, and cost was the primary barrier to both care seeking and attaining medications.