Start Network [to 17 October 2015]

Start Network [to 17 October 2015]
http://www.start-network.org/news-blog/#.U9U_O7FR98E
[Consortium of British Humanitarian Agencies]

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Crisis update: Internally displaced people and ongoing conflict in Afghanistan
October 16, 2015
Posted by Helen James in News.
On Monday 12 October, the Start Fund was alerted by Concern, Save the Children, Islamic Relief, Handicap International, Action Aid and Care to the surge in violence and resulting displacement of people in Northeast Afghanistan. Hostilities began in the region on 28 September with attacks by the Taliban in Kunduz city and later in Maimana.

Afghan forces have reportedly now regained control of most of Kunduz, but fighting continues in and around the city. Following the bombing of Kunduz hospital, run by MSF, US forces on 3 October, health services in the region are very limited. No other humanitarian organisations are operating in Kunduz city.

As a result of the ongoing conflict, approximately 16,000 families are displaced in Kunduz, Takhar, Balkh, Baghlan and Badakhsan provinces and in Kabul, and are in need of immediate assistance.

72 hours after being alerted the Start Fund’s project selection committee, which met in Kabul (with some participants joining virtually), awarded £440,000 to Christian Aid, Concern, Handicap International and Save the Children. Christian Aid and Handicap International will respond in Kunduz city reaching 4,200 and 1,500 beneficiaries respectively. Concern will respond in Takhar province reaching 6,372 beneficiaries. Save the Children will respond in Takhar province, Balkh province and Kunduz city reaching 5,055 beneficiaries.

 

CHS International Alliance [to 17 October 2015]

CHS International Alliance [to 17 October 2015]
http://chsalliance.org/news-events/news

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The CHS Alliance and the On the road to Istanbul report launched in Geneva
12/10/2015
The CHS Alliance as well as the On the road to Istanbul report – the Humanitarian Accountability report 2015 – were launched in Geneva last Friday, 9 October 2015, with over 60 participants from the humanitarian and development sector.

After opening speeches by the CHS Alliance’s Executive Director Judith Greenwood and the Alliance’s Chair Robert Glasser, a panel discussion was led by David Loquercio, the Head of Policy, Advocacy and Learning at the Alliance, with a focus on the humanitarian principles and collective accountability – two themes of the On the road to Istanbul report.

The panelists were:
:: Angharad Laing from Professionals in Humanitarian Assistance and Protection (PHAP)
:: Ingrid MacDonald from the Norwegian Refugee Council (NRC)
:: Loretta Hieber-Girardet from the UN Office for the Coordination of Humanitarian Affairs (OCHA)
:: Alyoscia D’Onofrio from the International Rescue Committee (IRC)

During the panel discussion, Angharad (PHAP) and Ingrid (NRC) both underlined that the humanitarian principles and humanitarian access were inextricably linked, with access being a precondition for high-quality and accountable assistance as well as essential for building trust and ensuring proximity to the affected population. Applying the principles therefore allowed to provide aid where it’s needed, rather than just where humanitarian organisations are based…

Ebola treatment beds prevented thousands of new cases and deaths – EHLRA/R2HC

EHLRA/R2HC [to 17 October 2015]
http://www.elrha.org/resource-hub/news/

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Ebola treatment beds prevented thousands of new cases and deaths
Published on 13/10/2015
R2HC-funded research by the London School of Hygiene & Tropical Medicine, highlights the need for – and power of – research conducted during a humanitarian crisis.

In December 2013 the world’s largest epidemic of the Ebola virus broke out, affecting thousands of people in West Africa. New research by the London School of Hygiene & Tropical Medicine suggests that 57,000 Ebola cases were prevented up to February 2015 due to the introduction of treatment beds and estimate that 40,000 lives were saved in Sierra Leone.

This research, funded by ELRHA’s Research for Health in Humanitarian Crises (R2HC) programme, focused on the impact of beds due to limited available data on other control measures in some districts of Sierra Leone. The new research, published in the Proceedings of the National Academy of Sciences, estimates – through mathematical modelling – that the introduction of treatment beds just one month earlier could have prevented an additional 12,5000 Ebola cases and almost halved the outbreak…

Global Humanitarian Assistance (GHA) [to 17 October 2015]

Global Humanitarian Assistance (GHA) [to 17 October 2015]
http://www.globalhumanitarianassistance.org/

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Afghanistan, Kunduz
Report Synopsis
Date: 2015/10/13
On 13 October 2015 we responded to a funding alert in response to displacement and ongoing conflict in North East Afghanistan (Kunduz, Takhar, Balkh, Baghlan and Badakhsan provinces) and Kabul.

As a consequence of the crisis, approximately 13,000 families in the North East and 2,800 families in Kabul are believed to have been displaced.

According to UN Office for the Coordination of Humanitarian Affairs’ Financial Tracking Service, donors have committed or contributed US$281 million of humanitarian assistance to Afghanistan so far in 2015. The United States is the largest donor, having contributed US$93 million so far, more than 33% of total funding to date this year.

Read our full analysis of the current funding situation

ODI [to 17 October 2015]

ODI [to 17 October 2015]
http://www.odi.org/media

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International equity surge into sub-Saharan Africa set to continue – new report
News | 13 October 2015
The rapid growth in international private equity in the region is set to continue – but governments need stronger policies to manage the risks of financial instability.

Building resilience in Nepal through public-private partnerships
Research reports and studies | October 2015 | Barnaby Willitts-King et al.
This report from the WEF Global Agenda Council on Risk and Resilience explores how public-private partnerships helped – and can help – improve resilience in Nepal and other contexts.

Progress under scrutiny: poverty reduction in Pakistan
Research reports and studies | October 2015 | Amina Khan, Arif Naveed, Emma Samman, Moizza Binat Sarwar and Chris Hoy
According to official data, consumption-based poverty in Pakistan fell sharply between 1990 and 2010. However, these figures are the subject of debate and this report discusses the implications of the high levels of contestation over official poverty data and what is…

Sharing the fruits of progress: poverty reduction in Ecuador
Research reports and studies | October 2015 | Andrea Ordóñez, Emma Samman, Chiara Mariotti and Iván Marcelo Borja Borja
In Ecuador, extreme poverty has fallen from 20% in 2000 to just 4% today and the country’s income inequality is falling at twice the regional average. Our new case study looks at the drivers behind such impressive progress in tackling extreme poverty.

Pathways to earthquake resilience in China
Working and discussion papers | October 2015 | John Young; Cui Ke; Lena Dominelli, Timothy Sim, William Weizhong Chen, Ning Li, Ling Zhang, Zhao Bin, Yunxi Yang, Brian Tucker, Tony Zhang Jun, Patrick Zhang Jun
This report brings together the voices of different groups working to build China’s resilience to earthquakes – with a focus on rural communities in Shaanxi Province.

Good Practice Review on disaster risk reduction
Research reports and studies | October 2015 | John Twigg
Disasters happen all the time. We can’t always prevent them from happening, but disaster risk reduction efforts can limit the scale of devastation.

10 international development priorities for the UK: parliamentary briefing
Briefing papers | October 2015
This briefing identifies 10 areas that need to be a priority for the UK government.

Creating a paradigm shift: statement for the World Humanitarian Summit Global Consultation
Briefing papers | October 2015
In the lead up to the Global Consultation for the World Humanitarian Summit, this statement outlines the need for a paradigm shift in the humanitarian system.

Gender and resilience
Research reports and studies | October 2015 | Emily Wilkinson, Virginie Le Masson and Andrew Norton
This paper reviews different approaches to incorporating gender equality objectives into climate resilience projects using a sample of project proposals from the BRACED programme.

Shaping economic transformation in Tanzania
Working and discussion papers | October 2015 | Dirk Willem te Velde, Sam Wangwe, Steve Wiggins, Benno Ndulu, Alison Brown, Peter Mackie, Alastair Smith, Colman Msoka, Emmanuel Mung’ong’o, Julius Gatune
DEGRP policy essays exploring the challenges of and potential solutions for economic transformation and ongoing economic growth in Tanzania.

Fiscal redistribution in developing countries: policy issues and options
Books or book chapters | October 2015 | Francesca Bastagli, David Coady and Sanjeev Gupta
Francesca Bastagli, David Coady and Sanjeev Gupta look at fiscal redistribution in developing countries in the International Monetary Fund’s book, Inequality and Fiscal Policy.

How humanitarian standards make a difference in the refugee crisis – Sphere Project

The Sphere Project [to 17 October 2015]
http://www.sphereproject.org/news/

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How humanitarian standards make a difference in the refugee crisis
13 October 2015 | Sphere Project
From Gaziantep in Turkey to Calais in France to several German cities, humanitarian standards are taking centre stage in the response to an unprecedented crisis… with no end in sight …
..OCHA Turkey recognises the need to train humanitarian staff to work with the Sphere Handbook. Thus the agency – in collaboration with CARE, Save the Children and the Sphere office – organised an experts workshop to customise the Sphere training package to the Syrian context.

The workshop took place in Gaziantep, some 40 km north of the Syrian border in late July. Integrating field examples from Syria, it demonstrated the applicability of Sphere standards and indicators to the Syrian humanitarian response while highlighting potential challenges linked to the specifics of the crisis.

The workshop outlined an action plan for the dissemination of Sphere standards through customised Sphere training activities in Arabic. These activities will target staff of international and national NGOs working in the Syrian response, be it inside Syria or across the border in Jordan, Lebanon and Iraq.

A three-day training activity took place already in July; two more, as well as a training of trainers course, are planned for the end of 2015. A Sphere reference group in Turkey is being set up and will work closely with the Sphere country focal points…

Download the workshop report Customisation of Sphere training modules to the Syrian context.

Conrad N. Hilton Foundation Announces Recipient of World’s Largest Humanitarian Prize – Landesa

Conrad N. Hilton Foundation [to 17 October 2015]
http://www.hiltonfoundation.org/news

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Press Release
Conrad N. Hilton Foundation Announces Recipient of World’s Largest Humanitarian Prize
(New York) Oct. 14, 2015 – The Conrad N. Hilton Foundation announced that its distinguished panel of independent international jurors has selected Landesa, a Seattle-based land rights organization, as the recipient of the largest humanitarian prize in the world – the Hilton Humanitarian Prize. As the 2015 Hilton Humanitarian Prize recipient, Landesa will receive $2 million in unrestricted funding and join the Hilton Prize Coalition, which was established in celebration of the 20th anniversary of the Hilton Prize and is comprised of all 20 Hilton Prize Laureate organizations.

“Landesa’s vision is a world free of extreme poverty—a vision made possible by securing land rights for some of the most vulnerable and disadvantaged people throughout the world,” said Conrad N. Hilton Foundation President and CEO Steven Hilton. “We are proud to recognize Landesa for its dedication to lifting individuals, their families, and entire communities out of poverty, and we know that the organization will put the Hilton Prize to good use.” …

MacArthur Foundation [to 17 October 2015]

MacArthur Foundation [to 17 October 2015]
http://www.macfound.org/

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Publication
Assessing Justice Reform Progress in Mexico
Published October 14, 2015
Despite obstacles to the implementation of sweeping judicial reform in Mexico, significant progress has been made and is likely to continue, according to a report from the University of San Diego’s Justice in Mexico initiative. The MacArthur-supported report provides a deep analysis of the current process of judicial reform in Mexico, the impacts of reform on the federal and state level, and past, present, and future challenges to implementation efforts.

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Press release
MacArthur Spins Off Digital Media & Learning Work with $25 Million Seed Investment
Published October 6, 2015
MacArthur today announced the launch of Collective Shift, a new nonprofit whose mission is to redesign social systems for the connected age. With $25 million in seed funding, Collective Shift’s first project is LRNG, which is creating a 21st century ecosystem of learning that combines in-school, out-of-school, work-based, and online learning opportunities that are visible and accessible to all.

With LRNG, Collective Shift builds on more than $200 million in research, design experiments, and demonstrations that MacArthur supported over the past decade. The goal of that work was to understand how young people are learning with digital media and what the implications are for how learning is designed and supported to ensure more equitable access to opportunity for success…

European Commission Must Ensure EU Investments Do Not Segregate People with Disabilities

Open Society Foundation [to 17 October 2015]
http://www.opensocietyfoundations.org/termsearch/8175/listing?f[0]=type%3Anews

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European Commission Must Ensure EU Investments Do Not Segregate People with Disabilities
October 13, 2015 News
BUDAPEST—A new report by the Open Society Foundations details the role of the European Commission in ensuring that member states do not spend EU structural funds to confine people with disabilities to long-stay institutions.

“Laws and procedures around structural funds may be complicated, but the reality is simple,” said Judith Klein, director of the Mental Health Initiative of the Open Society Foundations. “These investments must protect the right of every EU citizen to live in the community.”

The report, Community Not Confinement: The Role of the European Union in Promoting and Protecting the Right of People with Disabilities to Live in the Community, warns that although member states have agreed to move away from institutional care, some continue to invest in scaled-down facilities rather than supportive community living. This violates the UN Convention on the Rights of Persons with Disabilities (CRPD)…

David and Lucile Packard Foundation [to 17 October 2015]

David and Lucile Packard Foundation [to 17 October 2015]
http://www.packard.org/news/

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Educare California at Silicon Valley Opens its Doors
October 16, 2015
Educare California at Silicon Valley celebrated a new era of early learning opportunities for children in California during the new school’s ribbon-cutting ceremony held today.

Students, parents, community members, partner organizations and early education champions at the local, state and national levels noted the innovative new school’s impact on the community’s youngest learners and their families — and on the broader educational landscape for California.

Educare California at Silicon Valley currently serves 168 children ages 0 to 5 (with a future capacity to serve over 200) and their families in a model early learning school. It houses high-quality early learning classrooms, a family resource center, a satellite children’s museum, a career academy for high school students, and a professional development institute that will help reach thousands more children in the region…

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2015 Packard Fellowships in Science and Engineering Awarded to Eighteen Researchers
October 15, 2015
Today, the David and Lucile Packard Foundation named 18 of the nation’s most innovative early-career scientists and engineers as recipients of the 2015 Packard Fellowships for Science and Engineering. Each Fellow will receive a grant of $875,000 over five years to pursue their research.

“The Packard Fellowships give some of the most talented, early-career scientists and engineers the flexibility to experiment, take risks and explore new ideas that they otherwise may not have the resources to do,” said Dr. Frances Arnold, Dickinson Professor of Chemical Engineering, Bioengineering and Biochemistry and Director of the Donna and Benjamin M. Rosen Bioengineering Center at the California Institute of Technology (Caltech), and Chair of the Packard Fellowships Advisory Panel. “This type of investment in the nation’s best and brightest was something that David Packard believed would help to accelerate scientific breakthrough and in turn, provide many benefits to our society.”…

How China Could Change the Future of Antarctica’s Southern Ocean – Pew

Pew Charitable Trusts [to 17 October 2015]
http://www.pewtrusts.org/en/about/news-room/press-releases

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Opinion
How China Could Change the Future of Antarctica’s Southern Ocean
October 16, 2015
Antarctica may be one of the coldest and harshest places on Earth, but it is teeming with life. This is especially true in the Southern Ocean, where penguins, whales, leopard seals, toothfish, and a plethora of other marine life have thrived, largely undisturbed by humans—due to both the region’s remote location and the existence of multinational agreements that limit fishing.

But this unique environment now faces a triple threat: industrial fishing, climate change, and an effort to undermine the protections originally agreed to by the Commission for the Conservation of Antarctic Marine Living Resources (CCAMLR) a consensus-based fisheries management organization established in 1982.

While no single country can unilaterally determine the fate of the Southern Ocean, one nation—China—can play a major role in helping to safeguard this stunningly beautiful region…

A survey of Ethiopian physicians’ experiences of bedside rationing: extensive resource scarcity, tough decisions and adverse consequences

BMC Health Services Research
http://www.biomedcentral.com/bmchealthservres/content
(Accessed 17 October 2015)

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Research article
A survey of Ethiopian physicians’ experiences of bedside rationing: extensive resource scarcity, tough decisions and adverse consequences
Frehiwot Defaye, Dawit Desalegn, Marion Danis, Samia Hurst, Yemane Berhane, Ole Norheim, Ingrid Miljeteig BMC Health Services Research 2015, 15:467 (14 October 2015)
Abstract
Background
Resource scarcity in health care is a universal challenge. In high-income settings, bedside rationing is commonly discussed and debated as a means to addressing scarcity. However, little is known about physicians’ experiences in resource-limited contexts in low- income countries. Here we describe physicians’ experiences regarding scarcity of resources, bedside rationing, use of various strategies to save resources, and perceptions of the consequences of rationing in Ethiopia.
Methods
A national survey was conducted amongst physicians from 49 public hospitals using stratified, multi-stage sampling in six regions. All physicians in the selected hospitals were invited to respond to a self-administered questionnaire. Data were weighted and analyzed using descriptive statistics.
Results
In total, 587 physicians responded (91 % response rate). The majority had experienced system-wide shortages of various types of medical services. The services most frequently reported to be in short supply, either daily or weekly, were access to surgery, specialist and intensive care units, drug prescriptions and admission to hospital (52, 49, 46, 47 and 46 % respectively). The most common rationing strategies used daily or weekly were limiting laboratory tests, hospital drugs, radiological investigations and providing second best treatment (47, 47, 47 and 39 % respectively). Availability of institutional or national guidelines for whom to see and treat first was lacking. Almost all respondents had witnessed different adverse consequences of resource scarcity; 54 % reported seeing patients who, in their estimation, had died due to resource scarcity. Almost 9 out of 10 physicians were so troubled by limited resources that they often regretted their choice of profession.
Conclusion
This study provides the first glimpses of the untold story of resource shortage and bedside rationing in Ethiopia. Physicians encounter numerous dilemmas due to resource scarcity, and they report they lack adequate guidance for how to handle them. The consequences for patients and the professionals are substantial.

The importance of values in evidence-based medicine

BMC Medical Ethics
http://www.biomedcentral.com/bmcmedethics/content
(Accessed 17 October 2015)

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Debate
The importance of values in evidence-based medicine
Michael Kelly, Iona Heath, Jeremy Howick, Trisha Greenhalgh BMC Medical Ethics 2015, 16:69 (12 October 2015)
Abstract
Background
Evidence-based medicine (EBM) has always required integration of patient values with ‘best’ clinical evidence. It is widely recognized that scientific practices and discoveries, including those of EBM, are value-laden. But to date, the science of EBM has focused primarily on methods for reducing bias in the evidence, while the role of values in the different aspects of the EBM process has been almost completely ignored.
Discussion
In this paper, we address this gap by demonstrating how a consideration of values can enhance every aspect of EBM, including: prioritizing which tests and treatments to investigate, selecting research designs and methods, assessing effectiveness and efficiency, supporting patient choice and taking account of the limited time and resources available to busy clinicians. Since values are integral to the practice of EBM, it follows that the highest standards of EBM require values to be made explicit, systematically explored, and integrated into decision making.
Summary
Through ‘values based’ approaches, EBM’s connection to the humanitarian principles upon which it was founded will be strengthened.

BMC Pregnancy and Childbirth (Accessed 17 October 2015)

BMC Pregnancy and Childbirth
http://www.biomedcentral.com/bmcpregnancychildbirth/content
(Accessed 17 October 2015)

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Research article
Longitudinal adherence to antiretroviral drugs for preventing mother-to-child transmission of HIV in Zambia
Sumiyo Okawa, Mable Chirwa, Naoko Ishikawa, Henry Kapyata, Charles Msiska, Gardner Syakantu, Shinsuke Miyano, Kenichi Komada, Masamine Jimba, Junko Yasuoka BMC Pregnancy and Childbirth 2015, 15:258 (12 October 2015)

Research article
A case series study on the effect of Ebola on facility-based deliveries in rural Liberia
Jody Lori, Sarah Rominski, Joseph Perosky, Michelle Munro, Garfee Williams, Sue Bell, Aloysius Nyanplu, Patricia Amarah, Carol Boyd BMC Pregnancy and Childbirth 2015, 15:254 (12 October 2015)

Practical tools for improving global primary care

British Medical Journal
17 October 2015 (vol 351, issue 8029)
http://www.bmj.com/content/351/8029

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Editorials
Practical tools for improving global primary care
BMJ 2015; 351 doi: http://dx.doi.org/10.1136/bmj.h5361 (Published 13 October 2015)
[Initial text]
Universal health coverage can be achieved only by strengthening primary care, and new tools are needed
The sustainable development goals launched last month commit the world to achieving universal health coverage by 2030.1 Achievement will depend on providing high quality primary healthcare. Last month also saw the launch of a new partnership, the Primary Health Care Performance Initiative (www.phcperformanceinitiative.org), which aims to strengthen primary care in low and middle income countries through enhanced monitoring and sharing of best practices and tools. But the few practical tools that currently exist are often inadequate. We need better integrated, concise, and user friendly materials that can help health workers manage the wide range of problems seen in primary care.
For the past three decades, the World Health Organization has led the development of practical tools for primary care with the publication of charts, handbooks, and intervention guides for use by health workers with limited resources and training. The guidelines of the 1990s advised empirical treatments with essential medicines for clusters of symptoms and covered sexually transmitted infections2 and life threatening illnesses in young children.3 In the 2000s this approach was replicated for pregnancy and childbirth4 and respiratory conditions. …

Trade liberalization, social policies and health: an empirical case study

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 17 October 2015]

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Research
Trade liberalization, social policies and health: an empirical case study
McNamara C Globalization and Health 2015, 11:42 (12 October 2015)
Abstract
Background
This study investigates the health impacts of a major liberalization episode in the textile and clothing (T&C) sector. This episode triggered substantial shifts in employment across a wide range of countries. It is the first study to empirically link trade liberalization to health via changes in employment and offers some of the first empirical insights on how trade liberalization interacts with social policies to influence health.
Methods
Data from 32 T&C reliant countries were analysed in reference to the pre- and post-liberalization periods of 2000–2004 and 2005–2009. Fuzzy-set qualitative comparative analysis (fsQCA) was used to examine the association between countries’ a) level of development b) labour market and welfare state protections c) T&C employment changes and d) changes in adult female and infant mortality rates. Process tracing was used to further investigate these associations through twelve in-depth country studies.
Results
Results from the fsQCA relate changes in employment after the phase-out to both changing adult female and infant mortality rates. Findings from the in-depth country studies suggest that the worsening of adult female mortality rates is related to workers’ lack of social protection, both in the context of T&C employment growth and loss.
Conclusions
Overall, it is found that social protection is often inaccessible to the type of workers who may be the most vulnerable to processes of liberalization and that many workers are particularly vulnerable due to the structure of social protection policies. Social policies are therefore found to both moderate pathways to health and influence the type of health-related pathways resulting from trade liberalizing policies

“Flypaper effects” in transfers targeted to women: Evidence from BRAC’s “Targeting the Ultra Poor” program in Bangladesh

Journal of Development Economics
Volume 117, Pages 1-170 (November 2015)
http://www.sciencedirect.com/science/journal/03043878/115

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“Flypaper effects” in transfers targeted to women: Evidence from BRAC’s “Targeting the Ultra Poor” program in Bangladesh
Original Research Article
Pages 1-19
Shalini Roy, Jinnat Ara, Narayan Das, Agnes R. Quisumbing
Highlights
:: We evaluate a randomized water education campaign in South African townships.
:: Treated households were more likely to pay their water bill and paid 25% more.
:: The treatment did not operate by increasing consumers’ information.
:: Nonpayment can be reduced by strategies other than increased enforcement.
Abstract
Many development interventions target transfers to women. However, little evidence directly explores the “flypaper effects” of whether women retain control over these transfers once within the household and how reallocation of the transfers affects women’s empowerment. We study these dynamics in the context of BRAC’s randomized CFPR-TUP program in Bangladesh, which provides livestock and training to rural women in “ultra poor” households. Our analysis confirms previous findings that CFPR-TUP increased household asset ownership, but shows complex effects on targeted women. Women appear to retain ownership over transferred livestock, but new investments from mobilized resources are largely owned by men. CFPR-TUP also reduces women’s movement outside the home and control over income, consistent with transferred livestock requiring maintenance at home. However, beneficiary women also report “intangible” benefits such as increased social capital and, even with limited mobility, a preference for work inside the home given a hostile environment outside the home.

The Lancet Oct 17, 2015

The Lancet
Oct 17, 2015 Volume 386 Number 10003 p1509-1598 e18-e20
http://www.thelancet.com/journals/lancet/issue/current

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Editorial
Ageing and health—an agenda half completed
The Lancet
DOI: http://dx.doi.org/10.1016/S0140-6736(15)00521-8
The unprecedented increase in longevity across the world is a dividend from investment in health and progressive socioeconomic policies. It should be the source of celebration and pride; yet, the very systems that fostered longevity now risk squandering that success—and shaming themselves—because they are not aligned to the challenges and opportunities of older populations. To make healthy ageing a reality, radical changes are required in the education, organisation, and delivery of health care. The Lancet Series on ageing, published in 2014, outlined the challenges; now WHO’s World report on ageing and health, published Sept 30, guides the public health response.

The report avoids rigid age-definitions that perpetuate discrimination. Instead, it emphasises the heterogeneity of individuals and the importance of functional ability, rather than chronological age. Key domains that optimise functional ability are basic needs, autonomy, mobility, relationships, and contribution to society. Much of the diversity observed in older age is a consequence of social determinants and the advantages and disadvantages that accumulate across an individual’s life course. The authors consider how these factors can be influenced through environmental strategies, the delivery of health and long-term care, and policy.

Environment is formed not only by physical location, but also by government policies and societal attitudes. Environments are dynamic and can modify the trajectory of functional ability in older age by influencing an individual’s physical and mental capacity as either a facilitator or barrier to healthy ageing. They go beyond housing (which should be affordable, safe, and accessible), to include transport, cultural and community factors, opportunities for physical activity, and exposure to tobacco and other harmful materials.

Historically, health-care systems were designed to address isolated acute episodes of illness, rather than to manage the chronic multimorbidity that becomes increasingly common with age. So disappointed with their experience of care was one WHO sample of older patients from high-income countries, that it dissuaded almost a quarter of them from seeking care at a subsequent episode. A total change is called for, from improving the skills and understanding of health-care providers to a more age-friendly, holistic, integrated, sustainable, and dignified approach that focuses care across a range of services on common priorities identified by the individual. While such a role might seem tailored for primary care, it requires underpinning from adequately supported centres of expertise in geriatric care and a cadre of trained care-providers. A further weakness of current approaches is that non-clinical carers are often inadequately prepared, resourced, and respected for their role.

Changes are also necessary in the organisation of health care. Just as it seems unimaginable to deliver equitable care of high quality to older people in the absence of universal health coverage, some form of integrated and affordable social support in old age will also be required. To demonstrate the simultaneous acuteness and distance of that goal, the UK released figures on Oct 6 showing that only a minority of the 1·85 million requests for social services in the previous financial year, 72% of which came from people aged older than 65 years, could be supported by local councils.

The report is a welcome catalyst for much-needed research in the care of older people. The messages are relevant to all practitioners and health systems, particularly in middle-income and low-income countries where, by 2050, 80% of people aged older than 60 years will live. To translate the report into action, WHO is working with Member States to develop a global strategy and action plan, which is open for a web consultation until Oct 30. Engagement at high levels is important, including linkage with the Sustainable Development Goals for inclusiveness and wellbeing. However, just as older people will each have unique needs and preferences, so, too, countries will need to adapt their own health systems to local needs and circumstances.

At present only one country, Japan, has more than 30% of its population aged older than 60 years. By 2050, there will be many, including Chile, China, Iran, and Thailand. Opportunities for shared learning abound, such as the ongoing Joint Research Network on Ageing and Health in Asia, a multidisciplinary, multicountry collaboration, organised jointly by Mahidol University and the University of Tokyo that meets in Bangkok on Oct 22. Sharing perspectives and ideas in similar gatherings will create the environment from which local innovative solutions arise.

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Comment
Maternal, newborn, and child health and the Sustainable Development Goals—a call for sustained and improved measurement
John Grove, Mariam Claeson, Jennifer Bryce, Agbessi Amouzou, Ties Boerma, Peter Waiswa, Cesar Victora, Kirkland Group
DOI: http://dx.doi.org/10.1016/S0140-6736(15)00517-6
Immunisation is one of the great global health successes of the past century, with millions of lives saved.1 Ensuring vaccination of millions of children is complex, but is made possible by one fundamental task: systematic counting at multiple levels and at frequent intervals. From charts in thousands of rural health posts, to databases in ministries of health, to standardised surveys and global reports from WHO, UNICEF, and GAVI, the Vaccine Alliance, a robust interconnected system of data collection and use enables health workers, programme managers, and global actors to track who is vaccinated and make course corrections as needed to improve performance, policies, and programmes…

 

Complete Protection against Pneumonic and Bubonic Plague after a Single Oral Vaccination

PLoS Neglected Tropical Diseases
http://www.plosntds.org/
(Accessed 17 October 2015)

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Complete Protection against Pneumonic and Bubonic Plague after a Single Oral Vaccination
Anne Derbise, Yuri Hanada, Manal Khalifé, Elisabeth Carniel, Christian E. Demeure
Research Article | published 16 Oct 2015 | PLOS Neglected Tropical Diseases
10.1371/journal.pntd.0004162
Abstract
Background
No efficient vaccine against plague is currently available. We previously showed that a genetically attenuated Yersinia pseudotuberculosis producing the Yersinia pestis F1 antigen was an efficient live oral vaccine against pneumonic plague. This candidate vaccine however failed to confer full protection against bubonic plague and did not produce F1 stably.
Methodology/Principal Findings
The caf operon encoding F1 was inserted into the chromosome of a genetically attenuated Y. pseudotuberculosis, yielding the VTnF1 strain, which stably produced the F1 capsule. Given orally to mice, VTnF1 persisted two weeks in the mouse gut and induced a high humoral response targeting both F1 and other Y. pestis antigens. The strong cellular response elicited was directed mostly against targets other than F1, but also against F1. It involved cells with a Th1—Th17 effector profile, producing IFNγ, IL-17, and IL-10. A single oral dose (108 CFU) of VTnF1 conferred 100% protection against pneumonic plague using a high-dose challenge (3,300 LD50) caused by the fully virulent Y. pestis CO92. Moreover, vaccination protected 100% of mice from bubonic plague caused by a challenge with 100 LD50 Y. pestis and 93% against a high-dose infection (10,000 LD50). Protection involved fast-acting mechanisms controlling Y. pestis spread out of the injection site, and the protection provided was long-lasting, with 93% and 50% of mice surviving bubonic and pneumonic plague respectively, six months after vaccination. Vaccinated mice also survived bubonic and pneumonic plague caused by a high-dose of non-encapsulated (F1-) Y. pestis.
Significance
VTnF1 is an easy-to-produce, genetically stable plague vaccine candidate, providing a highly efficient and long-lasting protection against both bubonic and pneumonic plague caused by wild type or un-encapsulated (F1-negative) Y. pestis. To our knowledge, VTnF1 is the only plague vaccine ever reported that could provide high and durable protection against the two forms of plague after a single oral administration.
Author Summary
Yersinia pestis, the agent of plague, is among the deadliest infectious agents affecting humans. Injected in the skin by infected fleas, Y. pestis causes bubonic plague, which occasionally evolves into the very lethal and contagious pneumonic plague. Y. pestis is also a dangerous potential bioweapon but no plague vaccine is available. The current study describes the development of a vaccine highly efficient against plague in both its bubonic and pneumonic forms. The strategy consists of a live, avirulent, genetically modified Yersinia pseudotuberculosis that produces the capsule antigen of Y. pestis, named F1. The goal was to propose a vaccine that would be both easy to produce rapidly in large amounts with high quality, and easy to administer to individuals via a single oral dose. The VTnF1 strain described fulfills these demands. The immune response generated is long-lasting, involving both antibodies and memory cells directed against F1 and other antigens. We conclude that VTnF1 is a very promising candidate vaccine against plague.

Measuring the impact of Ebola control measures in Sierra Leone

PNAS – Proceedings of the National Academy of Sciences of the United States of America
http://www.pnas.org/content/early/
(Accessed 17 October 2015)

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Biological Sciences – Population Biology:
Measuring the impact of Ebola control measures in Sierra Leone
Adam J. Kucharski, Anton Camacho, Stefan Flasche, Rebecca E. Glover, W. John Edmunds, and Sebastian Funk
PNAS 2015 ; published ahead of print October 12, 2015, doi:10.1073/pnas.1508814112
Significance
Between June 2014 and February 2015, thousands of Ebola treatment beds were introduced in Sierra Leone, alongside other infection control measures. However, there has been criticism of the timing and focus of this response, and it remains unclear how much it contributed to curbing the 2014–2015 Ebola epidemic. Using a mathematical model, we estimated how many Ebola virus disease cases the response averted in each district of Sierra Leone. We estimated that 56,600 (95% credible interval: 48,300–84,500) Ebola cases were averted in Sierra Leone as a direct result of additional treatment beds. Moreover, the number of cases averted would have been even greater had beds been available 1 month earlier.
Abstract
Between September 2014 and February 2015, the number of Ebola virus disease (EVD) cases reported in Sierra Leone declined in many districts. During this period, a major international response was put in place, with thousands of treatment beds introduced alongside other infection control measures. However, assessing the impact of the response is challenging, as several factors could have influenced the decline in infections, including behavior changes and other community interventions. We developed a mathematical model of EVD transmission, and measured how transmission changed over time in the 12 districts of Sierra Leone with sustained transmission between June 2014 and February 2015. We used the model to estimate how many cases were averted as a result of the introduction of additional treatment beds in each area. Examining epidemic dynamics at the district level, we estimated that 56,600 (95% credible interval: 48,300–84,500) Ebola cases (both reported and unreported) were averted in Sierra Leone up to February 2, 2015 as a direct result of additional treatment beds being introduced. We also found that if beds had been introduced 1 month earlier, a further 12,500 cases could have been averted. Our results suggest the unprecedented local and international response led to a substantial decline in EVD transmission during 2014–2015. In particular, the introduction of beds had a direct impact on reducing EVD cases in Sierra Leone, although the effect varied considerably between districts.