Nature
Volume 524 Number 7565 pp265-382 20 August 2015
http://www.nature.com/nature/current_issue.html
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World View
Tackle Nepal’s typhoid problem now
As post-earthquake conditions increase the risk of a typhoid epidemic, Buddha Basnyat calls for a widespread vaccination programme.

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Volume 524 Number 7564 pp137-260 13 August 2015
http://www.nature.com/nature/journal/v524/n7564/index.html
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Volume 524 Number 7563 pp5-130 6 August 2015
http://www.nature.com/nature/journal/v524/n7563/index.html
Editorial
Trial and triumph
The success of an Ebola vaccine trial shows that clinical trials can be done under the difficult field conditions of an epidemic — if there is enough political and regulatory will.

World View
Train Africa’s scientists in crisis response
To prevent future epidemics, a new international effort must boost West Africa’s scientific and public-health capacity, says Christian Bréchot.

Comment
Disease outbreak: Finish the fight against Ebola
Leaders and health agencies are talking about ‘lessons learned’ from West Africa’s Ebola epidemic. But a major push is needed to end the outbreak, urges Joanne Liu.

Ebola: Embed research in outbreak response
Testing Ebola treatments in West Africa’s epidemic happened too late. Research response during future outbreaks must be more nimble, says Trudie Lang.

Articles
Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone Open
Yi-Gang Tong, Wei-Feng Shi, Di Liu, Jun Qian, Long Liang+ et al.
The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous outbreaks and that the genetic diversity of the virus has increased substantially, with the emergence of several novel lineages.

Temporal and spatial analysis of the 2014–2015 Ebola virus outbreak in West Africa Open
Miles W. Carroll, David A. Matthews, Julian A. Hiscox, Michael J. Elmore, Georgios Pollakis
+ et al.
Analysis of 179 new Ebola virus sequences from patient samples collected in Guinea between March 2014 and January 2015 shows how different lineages evolved and spread in West Africa.

Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone Open
Yi-Gang Tong, Wei-Feng Shi, Di Liu, Jun Qian, Long Liang+ et al.
The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous outbreaks and that the genetic diversity of the virus has increased substantially, with the emergence of several novel lineages.