The Lancet
Apr 25, 2015 Volume 385 Number 9978 p1591-1696 e38-e44
http://www.thelancet.com/journals/lancet/issue/current

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Editorial
Vaccines: a step change in malaria prevention?
The Lancet
According to WHO’s 2014 World Malaria Report there were an estimated 198 million cases of malaria worldwide in 2013, occurring in around half of the world’s countries. These infections resulted in some 584 000 deaths, principally associated with Plasmodium falciparum infection, of which 90% occurred in equatorial Africa. Most distressingly, malaria mortality is concentrated in children, with about 453 000 deaths of children aged younger than 5 years in 2013, the vast majority in African countries.