JAMA
December 24/31, 2014, Vol 312, No. 24
http://jama.jamanetwork.com/issue.aspx

The 2014 Ebola Outbreak and Mental Health: Current Status and Recommended Response
James M. Shultz, MS, PhD, Florence Baingana, MB, ChB, MMed (Psychiatry), MSc (HPPF), Yuval Neria, PhD.
JAMA. Published online December 22, 2014. doi:10.1001/jama.2014.17934

Editorial | December 24/31, 2014
2015 Theme Issue on Trauma Associated With Violence and Human Rights Abuses
Call for Papers FREE
Annette Flanagin, RN, MA1; Thomas B. Cole, MD, MPH2,3
Author Affiliations
JAMA. 2014;312(24):2627-2628. doi:10.1001/jama.2014.16413.
Excerpt
In August 2015, JAMA will publish a theme issue on violence and human rights with an emphasis on the causes, consequences, and management of trauma. Violence is an important cause of physical and emotional trauma, and the scope of trauma care is broad, including care for survivors of unintentional injuries as well as injuries resulting from many forms of violence. Injuries and violence cause 5.8 million deaths each year worldwide, accounting for about 10% of the world’s deaths, more than the number of deaths that result from malaria, tuberculosis, and AIDS combined.1,2 The primary causes of these 5.8 million deaths are road traffic crashes, suicide, and homicide, followed by falls, drowning, poisoning, burns, and war.2 In the United States, data from the Global Burden of Disease 2010 Study indicate the following among the leading diseases and injuries contributing to premature mortality: road injury (fifth leading cause), self-harm (sixth), and interpersonal violence (12th).3 For the 2015 JAMA theme issue, we are soliciting papers on trauma resulting from unintentional and intentional injury, from interpersonal and community-levels of violence, and from mass conflict, war, displacement, and natural disasters…

Effect of Maternal Multiple Micronutrient vs Iron–Folic Acid Supplementation on Infant Mortality and Adverse Birth Outcomes in Rural Bangladesh: The JiVitA-3 Randomized Trial
Keith P. West Jr, DrPH; Abu Ahmed Shamim, MSc; Sucheta Mehra, MS; Alain B. Labrique, PhD; Hasmot Ali, MBBS, MPH; Saijuddin Shaikh, PhD, MPH; Rolf D. W. Klemm, DrPH; Lee S-F. Wu, MHS; Maithilee Mitra, MS; Rezwanul Haque, MA; Abu A. M. Hanif, MBBS; Allan B. Massie, PhD; Rebecca Day Merrill, PhD; Kerry J. Schulze, PhD; Parul Christian, DrPH, MSc
Importance
Maternal micronutrient deficiencies may adversely affect fetal and infant health, yet there is insufficient evidence of effects on these outcomes to guide antenatal micronutrient supplementation in South Asia.
Objective
To assess effects of antenatal multiple micronutrient vs iron–folic acid supplementation on 6-month infant mortality and adverse birth outcomes.
Design, Setting, and Participants
Cluster randomized, double-masked trial in Bangladesh, with pregnancy surveillance starting December 4, 2007, and recruitment on January 11, 2008. Six-month infant follow-up ended August 30, 2012. Surveillance included 127 282 women; 44 567 became pregnant and were included in the analysis and delivered 28 516 live-born infants. Median gestation at enrollment was 9 weeks (interquartile range, 7-12).
Interventions
Women were provided supplements containing 15 micronutrients or iron–folic acid alone, taken daily from early pregnancy to 12 weeks postpartum.
Main Outcomes and Measures
The primary outcome was all-cause infant mortality through 6 months (180 days). Prespecified secondary outcomes in this analysis included stillbirth, preterm birth (<37 weeks), and low birth weight (<2500 g). To maintain overall significance of α = .05, a Bonferroni-corrected α = .01 was calculated to evaluate statistical significance of primary and 4 secondary risk outcomes (.05/5).
Results
Among the 22 405 pregnancies in the multiple micronutrient group and the 22 162 pregnancies in the iron–folic acid group, there were 14 374 and 14 142 live-born infants, respectively, included in the analysis. At 6 months, multiple micronutrients did not significantly reduce infant mortality; there were 764 deaths (54.0 per 1000 live births) in the iron–folic acid group and 741 deaths (51.6 per 1000 live births) in the multiple micronutrient group (relative risk [RR], 0.95; 95% CI, 0.86-1.06). Multiple micronutrient supplementation resulted in a non–statistically significant reduction in stillbirths (43.1 vs 48.2 per 1000 births; RR, 0.89; 95% CI, 0.81-0.99; P = .02) and significant reductions in preterm births (18.6 vs 21.8 per 100 live births; RR, 0.85; 95% CI, 0.80-0.91; P < .001) and low birth weight (40.2 vs 45.7 per 100 live births; RR, 0.88; 95% CI, 0.85-0.91; P < .001).
Conclusions and Relevance
In Bangladesh, antenatal multiple micronutrient compared with iron–folic acid supplementation did not reduce all-cause infant mortality to age 6 months but resulted in a non–statistically significant reduction in stillbirths and significant reductions in preterm births and low birth weight.