The Lancet Infectious Diseases
Mar 2014  Volume 14  Number 3   p173 – 256
http://www.thelancet.com/journals/laninf/issue/current

Editorial
Pandemic potential of emerging influenza
The Lancet Infectious Diseases
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In January this year, the first case of highly pathogenic avian influenza H5N1 was detected in the Americas when a Canadian man returning from Beijing fell ill and subsequently died. January also saw a sharp upturn in the number of cases of H7N9 avian influenza in China with 169 cases detected in 1 month, compared with 144 up to the end of last year since it was first identified in March 2013. Another familiar virus, 2009 pandemic influenza A H1N1 has also been hitting the headlines in Egypt, where there have been over 300 cases and around 38 deaths since December, and in Mexico over 400 deaths have been associated with H1N1 this year.

Review
Pandemic influenza A H1N1 vaccines and narcolepsy: vaccine safety surveillance in action
Charlotte I S Barker, Matthew D Snape
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The 2009 influenza A H1N1 pandemic placed unprecedented demand on public health authorities and the vaccine industry. Efforts were coordinated internationally to maximise the speed of vaccine development, distribution, and delivery, and the European Union’s novel fast-track authorisation procedures mandated increased postmarketing surveillance to monitor vaccine safety. Clinicians in Finland and Sweden later identified an apparent increase in the incidence of narcolepsy associated with a specific adjuvanted pandemic influenza vaccine.